{
  "id": 10085,
  "label": "arterial calcification, generalized, of infancy, 1",
  "model": {
    "label": "Mondo Disease Ontology (MONDO)",
    "source": 0
  },
  "type_id": 0,
  "reference_id": "MONDO:0008817",
  "properties": {
    "xrefs": [
      "GARD:0024642",
      "MEDGEN:1631685",
      "NCIT:C128805",
      "OMIM:208000",
      "UMLS:C4551985"
    ],
    "synonyms": [
      "ENPP1 arterial calcification of infancy",
      "arterial calcification of infancy caused by mutation in ENPP1",
      "arterial calcification, generalized, of infancy, 1",
      "arterial calcification, generalized, of infancy, type 1",
      "generalised arterial calcification of infancy 1",
      "generalized arterial calcification of infancy 1",
      "GACI1",
      "Gaci",
      "arterial calcification, idiopathic infantile",
      "arteriopathy, occlusive infantile",
      "coronary sclerosis, medial, of infancy",
      "idiopathic infantile arterial calcification"
    ],
    "categories": [
      {
        "ref": "MONDO:0004995",
        "name": "cardiovascular disorder"
      }
    ],
    "definition": "An autosomal recessive genetic disorder caused by mutations in the ENPP1 gene, encoding ectonucleotide pyrophosphatase/phosphodiesterase family member 1. The condition is characterized by calcification and narrowing of medium- and large-sized arteries, resulting in cardiovascular complications."
  },
  "isLeaf": true,
  "isRoot": false,
  "child_count": 0,
  "parents": [
    {
      "id": 18802,
      "label": "arterial calcification of infancy",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        5714,
        7065
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:0050644",
          "GARD:0008380",
          "MEDGEN:395331",
          "MESH:C537440",
          "NORD:2001",
          "OMIMPS:208000",
          "Orphanet:51608",
          "UMLS:C1859727",
          "icd11.foundation:934461548"
        ],
        "synonyms": [
          "Generalized Arterial Calcification of Infancy",
          "generalised arterial calcification of infancy",
          "generalized arterial calcification of infancy",
          "idiopathic infantile arterial calcification",
          "idiopathic obliterative arteriopathy",
          "infantile arteriosclerosis",
          "occlusive infantile arteriopathy",
          "IIAC",
          "generalised arterial calcification in infancy",
          "generalized arterial calcification in infancy"
        ],
        "categories": [
          {
            "ref": "MONDO:0004995",
            "name": "cardiovascular disorder"
          }
        ],
        "definition": "Idiopathic arterial calcification of infancy is a rare condition characterized by extensive calcification and stenosis of the large and medium sized arteries."
      },
      "child_count": 4,
      "reference_id": "MONDO:0018870"
    }
  ],
  "children": [],
  "roots": [
    {
      "id": 18802,
      "label": "arterial calcification of infancy"
    }
  ]
}