{
  "id": 10550,
  "label": "lipodystrophy due to peptidic growth factors deficiency",
  "model": {
    "label": "Mondo Disease Ontology (MONDO)",
    "source": 0
  },
  "type_id": 0,
  "reference_id": "MONDO:0009312",
  "properties": {
    "xrefs": [
      "GARD:0012604",
      "MEDGEN:419375",
      "MESH:C565529",
      "OMIM:233805",
      "Orphanet:1979",
      "SCTID:724176001",
      "UMLS:C2931279",
      "icd11.foundation:1235390174"
    ],
    "synonyms": [
      "Hoepffner-Dreyer-Reimers syndrome",
      "Werner-like syndrome due to combined growth factor deficiency",
      "combined insulin, insulin-like growth factor 1 (IGF1) and epidermal growth factor (EGF) deficiency",
      "Hoepffner Dreyer Reimers syndrome",
      "Werner-like syndrome due to combined Growth Factor deficiency",
      "growth factors, combined defect OF",
      "insulin, insulin-like Growth Factor I, and Epidermal Growth Factor deficiency",
      "peptide growth factors deficiency",
      "peptidic growth factors deficiency"
    ],
    "categories": [
      {
        "ref": "MONDO:0002051",
        "name": "integumentary system disorder"
      }
    ],
    "definition": "Deficiency of the peptidic growth factors is characterized by loss of subcutaneous fat layers on the limbs, lipodystrophy in the face and trunk and scleroderma-like skin disorders (thickened skin on the palms and soles and skin pigment changes on the limbs and trunk)."
  },
  "isLeaf": true,
  "isRoot": false,
  "child_count": 0,
  "parents": [
    {
      "id": 19731,
      "label": "hereditary lipodystrophy",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        8053,
        18954,
        23867
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "GARD:0012597",
          "MEDGEN:1383706",
          "Orphanet:98305",
          "SCTID:724841000",
          "UMLS:C4511302",
          "icd11.foundation:1166232738"
        ],
        "synonyms": [
          "genetic lipodystrophy",
          "genetic lipodystrophy (disease)"
        ],
        "categories": [
          {
            "ref": "MONDO:0002051",
            "name": "integumentary system disorder"
          }
        ],
        "definition": "An instance of lipodystrophy that is caused by an inherited genomic modification in an individual."
      },
      "child_count": 33,
      "reference_id": "MONDO:0020087"
    }
  ],
  "children": [],
  "roots": [
    {
      "id": 19731,
      "label": "hereditary lipodystrophy"
    }
  ]
}