{
  "id": 10626,
  "label": "juvenile Paget disease",
  "model": {
    "label": "Mondo Disease Ontology (MONDO)",
    "source": 0
  },
  "type_id": 0,
  "reference_id": "MONDO:0009394",
  "properties": {
    "xrefs": [
      "DOID:0081368",
      "GARD:0002831",
      "MEDGEN:75678",
      "MESH:C537701",
      "NCIT:C131861",
      "NORD:1230",
      "OMIM:239000",
      "Orphanet:2801",
      "SCTID:9723006",
      "UMLS:C0268414",
      "icd11.foundation:762002965"
    ],
    "synonyms": [
      "Hereditary Hyperphosphatasia",
      "JPG",
      "familial hyperphosphatasia",
      "familial osteoectasia",
      "hereditary hyperphosphatasia",
      "hyperostosis corticalis deformans juvenilis",
      "juvenile Paget disease",
      "juvenile Paget's disease",
      "JPD",
      "PDB5",
      "Paget disease juvenile type",
      "Paget disease of bone 5, juvenile-onset",
      "hyperostosid corticalis deformans juvenilis",
      "hyperphosphatasemia, chronic congenital idiopathic",
      "hyperphosphatasia, familial idiopathic",
      "juvenile Pagets disease",
      "osteoectasia, familial"
    ],
    "categories": [
      {
        "ref": "MONDO:0002081",
        "name": "musculoskeletal system disorder"
      }
    ],
    "definition": "Juvenile Paget disease is a very rare form of Paget disease of the bone characterized by a general increase in bone turnover with increased bone resorption and deposition, resulting in cortical and trabecular thickening, and clinically presenting as progressive skeletal deformities, growth impairment, fractures, vertebral collapse, skull enlargement and sensorineural hearing loss."
  },
  "isLeaf": true,
  "isRoot": false,
  "child_count": 0,
  "parents": [
    {
      "id": 7062,
      "label": "bone Paget disease",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        4308,
        5714,
        25070
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:5408",
          "EFO:0004261",
          "ICD10CM:M88",
          "MEDGEN:10493",
          "NCIT:C3292",
          "OMIMPS:167250",
          "Orphanet:280110",
          "SCTID:2089002",
          "UMLS:C0029401"
        ],
        "synonyms": [
          "Paget disease of bone",
          "Paget's bone disease",
          "Paget's disease of bone",
          "Paget's disease of the bone",
          "Pagets disease (bone)",
          "bone Paget disease",
          "bone Paget's disease",
          "osseous Paget's disease",
          "osteitis deformans",
          "Paget's disease",
          "familial Paget's disease of bone"
        ],
        "categories": [
          {
            "ref": "MONDO:0002081",
            "name": "musculoskeletal system disorder"
          }
        ],
        "definition": "A disease of bone that initially results in the excessive resorption of bone (by osteoclasts) followed by the replacement of normal bone marrow with vascular and fibrous tissue."
      },
      "child_count": 15,
      "reference_id": "MONDO:0005382"
    }
  ],
  "children": [],
  "roots": [
    {
      "id": 7062,
      "label": "bone Paget disease"
    }
  ]
}