{
  "id": 10852,
  "label": "microspherophakia and/or megalocornea, with ectopia lentis and with or without secondary glaucoma",
  "model": {
    "label": "Mondo Disease Ontology (MONDO)",
    "source": 0
  },
  "type_id": 0,
  "reference_id": "MONDO:0009633",
  "properties": {
    "xrefs": [
      "MEDGEN:761238",
      "OMIM:251750",
      "UMLS:C3538951"
    ],
    "synonyms": [
      "microspherophakia and/or megalocornea, with ectopia lentis and with or without secondary glaucoma",
      "MSPKA"
    ],
    "categories": [
      {
        "ref": "MONDO:0002022",
        "name": "disorder of orbital region"
      },
      {
        "ref": "MONDO:0024458",
        "name": "disorder of visual system"
      }
    ]
  },
  "isLeaf": false,
  "isRoot": false,
  "child_count": 1,
  "parents": [
    {
      "id": 23976,
      "label": "LTBP2-related ocular dysgenesis",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        5714,
        7019
      ],
      "type_id": 0,
      "properties": {
        "categories": [
          {
            "ref": "MONDO:0002022",
            "name": "disorder of orbital region"
          },
          {
            "ref": "MONDO:0024458",
            "name": "disorder of visual system"
          }
        ],
        "definition": "Any ocular dysgenesis disorder in which the cause of the disease is a mutation in the LTBP2 gene."
      },
      "child_count": 6,
      "reference_id": "MONDO:0100236"
    }
  ],
  "children": [
    {
      "id": 17054,
      "label": "glaucoma secondary to spherophakia/ectopia lentis and megalocornea",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        10852,
        18318
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "GARD:0010942",
          "MEDGEN:1674483",
          "Orphanet:238763",
          "UMLS:C5190883"
        ],
        "synonyms": [
          "megalocornea-spherophakia-secondary glaucoma syndrome"
        ],
        "categories": [
          {
            "ref": "MONDO:0002022",
            "name": "disorder of orbital region"
          },
          {
            "ref": "MONDO:0024458",
            "name": "disorder of visual system"
          }
        ],
        "definition": "Glaucoma secondary to spherophakia/ectopia lentis and megalocornea is a rare, genetic, non-syndromic developmental defect of the eye disorder characterized by congenital megalocornea associated with spherophakia and/or ectopia lentis leading to pupillary block and secondary glaucoma. Additional features may include flat irides, iridodonesis, axial myopia, very deep anterior chambers, miotic, oval pupils without well-defined borders, ocular pain and irritability manifesting as conjunctival injection, corneal edema and central scarring, as well as a high arched palate."
      },
      "child_count": 0,
      "reference_id": "MONDO:0016559"
    }
  ],
  "roots": [
    {
      "id": 23976,
      "label": "LTBP2-related ocular dysgenesis"
    }
  ]
}