{
  "id": 10945,
  "label": "nephrotic syndrome, type 4",
  "model": {
    "label": "Mondo Disease Ontology (MONDO)",
    "source": 0
  },
  "type_id": 0,
  "reference_id": "MONDO:0009733",
  "properties": {
    "xrefs": [
      "DOID:0080383",
      "GARD:0015210",
      "MEDGEN:462918",
      "NCIT:C121198",
      "OMIM:256370",
      "UMLS:C3151568"
    ],
    "synonyms": [
      "WT1 nephrotic syndrome",
      "congenital nephrotic syndrome - diffuse mesangial sclerosis",
      "nephrotic syndrome caused by mutation in WT1",
      "nephrotic syndrome, type 4",
      "DMS",
      "NPHS4",
      "diffuse isolated mesangial sclerosis",
      "diffuse mesangial sclerosis",
      "familial mesangial sclerosis",
      "isolated diffuse mesangial sclerosis",
      "mesangial sclerosis, diffuse",
      "nephrotic syndrome, early onset with diffuse mesangial sclerosis"
    ],
    "categories": [
      {
        "ref": "MONDO:0002118",
        "name": "urinary system disorder"
      },
      {
        "ref": "MONDO:0002254",
        "name": "syndromic disease"
      }
    ],
    "definition": "Nephrotic syndrome within the first three motnhs of life, characterized initially by increased mesangial matrix, with or without hypertrophy and hyperplasia of podocytes, and eventual glomerular sclerosis."
  },
  "isLeaf": true,
  "isRoot": false,
  "child_count": 0,
  "parents": [
    {
      "id": 4449,
      "label": "familial nephrotic syndrome",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        7058,
        23932
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:2590",
          "GARD:0027602",
          "MEDGEN:502251",
          "NCIT:C35337",
          "OMIMPS:256300",
          "SCTID:48796009",
          "UMLS:C3501848",
          "icd11.foundation:1524476844"
        ],
        "synonyms": [
          "congenital nephrotic syndrome",
          "hereditary nephrotic syndrome"
        ],
        "categories": [
          {
            "ref": "MONDO:0002118",
            "name": "urinary system disorder"
          },
          {
            "ref": "MONDO:0002254",
            "name": "syndromic disease"
          }
        ],
        "definition": "An instance of nephrotic syndrome that is caused by an inherited modification of the individual's genome."
      },
      "child_count": 36,
      "reference_id": "MONDO:0002350"
    }
  ],
  "children": [],
  "roots": [
    {
      "id": 4449,
      "label": "familial nephrotic syndrome"
    }
  ]
}