{
  "id": 10984,
  "label": "cloacal exstrophy",
  "model": {
    "label": "Mondo Disease Ontology (MONDO)",
    "source": 0
  },
  "type_id": 0,
  "reference_id": "MONDO:0009774",
  "properties": {
    "xrefs": [
      "DOID:0080175",
      "GARD:0004080",
      "HP:0010475",
      "ICD9:759.89",
      "MEDGEN:83377",
      "MESH:C537748",
      "MedDRA:10067424",
      "NANDO:1200909",
      "NANDO:1200910",
      "NANDO:2200950",
      "NANDO:2200951",
      "Orphanet:93929",
      "SCTID:20815007",
      "UMLS:C0345217",
      "icd11.foundation:2004612103"
    ],
    "synonyms": [
      "cloacal exstrophy",
      "cloacal exstrophy (disease)",
      "omphalocele-cloacal exstrophy-imperforate anus-spinal defect syndrome",
      "OEIS complex",
      "OEIS syndrome",
      "cloacal exstrophy sequence",
      "omphalocele - cloacal exstrophy - imperforate anus - spinal defect",
      "omphalocele, exstrophy of the cloaca, imperforate anus, and spinal defects",
      "omphalocele, exstrophy of the cloaca, imperforate anus, and spinal defects complex",
      "omphalocele-exstrophy-imperforate anus-spinal defects"
    ],
    "categories": [
      {
        "ref": "MONDO:0002118",
        "name": "urinary system disorder"
      },
      {
        "ref": "MONDO:0002254",
        "name": "syndromic disease"
      }
    ],
    "definition": "A major birth defect representing the severe end of the spectrum of the exstrophy-epispadias complex (EEC) characterized by omphalocele, exstrophy, imperforate anus and spinal defects (also referred to as the OEIS complex), often associated with other malformations."
  },
  "isLeaf": true,
  "isRoot": false,
  "child_count": 0,
  "parents": [
    {
      "id": 4370,
      "label": "syndromic disease",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        29379
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:225",
          "MEDGEN:11688",
          "MESH:D013577",
          "NCIT:C28193",
          "OGMS:0000086",
          "UMLS:C0039082"
        ],
        "synonyms": [
          "cluster, symptom",
          "clusters, symptom",
          "symptom cluster",
          "symptom clusters",
          "syndrome",
          "syndrome associated with disease or disorder",
          "syndromes",
          "syndromic disease",
          "syndromic disease or disorder"
        ],
        "categories": [
          {
            "ref": "MONDO:0002254",
            "name": "syndromic disease"
          }
        ],
        "definition": "A group of signs, symptoms, and clinicopathological characteristics that may or may not have a genetic basis and collectively define an abnormal condition."
      },
      "child_count": 1182,
      "reference_id": "MONDO:0002254"
    },
    {
      "id": 18120,
      "label": "exstrophy-epispadias complex",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        6948,
        19192
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:0080173",
          "GARD:0002207",
          "MEDGEN:338020",
          "NCIT:C99142",
          "OMIM:258040",
          "Orphanet:322",
          "UMLS:C1850321"
        ],
        "synonyms": [
          "EEC",
          "OEIS complex",
          "OEIS syndrome",
          "BEEC",
          "bladder exstrophy-epispadias-cloacal extrophy complex"
        ],
        "categories": [
          {
            "ref": "MONDO:0002118",
            "name": "urinary system disorder"
          }
        ],
        "definition": "A spectrum of genitourinary malformations ranging in severity from epispadias (E) and classical bladder exstrophy (CEB) to exstrophy of the cloaca (EC) as the most severe form. Depending on severity, the EEC may involve the urinary system, the musculoskeletal system, the pelvis, the pelvic floor, the abdominal wall, the genitalia and sometimes the spine and the anus."
      },
      "child_count": 8,
      "reference_id": "MONDO:0017919"
    }
  ],
  "children": [],
  "roots": [
    {
      "id": 4370,
      "label": "syndromic disease"
    },
    {
      "id": 18120,
      "label": "exstrophy-epispadias complex"
    }
  ]
}