{
  "id": 11034,
  "label": "parkinsonian-pyramidal syndrome",
  "model": {
    "label": "Mondo Disease Ontology (MONDO)",
    "source": 0
  },
  "type_id": 0,
  "reference_id": "MONDO:0009830",
  "properties": {
    "xrefs": [
      "DOID:0060372",
      "GARD:0009175",
      "MEDGEN:337969",
      "MESH:C538104",
      "OMIM:260300",
      "Orphanet:171695",
      "UMLS:C1850100",
      "icd11.foundation:1128311778"
    ],
    "synonyms": [
      "Pallidopyramidal syndrome",
      "Parkinson disease 15, autosomal recessive",
      "autosomal recessive early-onset Parkinson disease type 15",
      "pallidopyramidal syndrome",
      "parkinsonian-pyramidal syndrome",
      "PARK15",
      "Parkinson disease 15, autosomal recessive early-onset",
      "autosomal recessive early-onset Parkinson's disease 15",
      "pallido-pyramidal disease",
      "pallido-pyramidal syndrome"
    ],
    "categories": [
      {
        "ref": "MONDO:0005071",
        "name": "nervous system disorder"
      }
    ],
    "definition": "A Parkinson's disease that has material basis in mutation in the FBXO7 gene on chromosome 22q12.3."
  },
  "isLeaf": false,
  "isRoot": false,
  "child_count": 1,
  "parents": [
    {
      "id": 6901,
      "label": "Parkinson disease",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        20335,
        24270
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:14330",
          "ICD10CM:G20",
          "ICD10WHO:G20",
          "ICD9:332",
          "ICD9:332.0",
          "MEDGEN:10590",
          "MESH:D010300",
          "NANDO:1200010",
          "NCIT:C26845",
          "OMIMPS:168600",
          "Orphanet:319705",
          "SCTID:49049000",
          "UMLS:C0030567",
          "birnlex:2098",
          "icd11.foundation:296066191"
        ],
        "synonyms": [
          "PD",
          "Parkinson disease",
          "Parkinson's disease",
          "paralysis agitans"
        ],
        "categories": [
          {
            "ref": "MONDO:0005071",
            "name": "nervous system disorder"
          }
        ],
        "definition": "A progressive degenerative disorder of the central nervous system characterized by loss of dopamine producing neurons in the substantia nigra and the presence of Lewy bodies in the substantia nigra and locus coeruleus. Signs and symptoms include tremor which is most pronounced during rest, muscle rigidity, slowing of the voluntary movements, a tendency to fall back, and a mask-like facial expression."
      },
      "child_count": 12,
      "reference_id": "MONDO:0005180"
    }
  ],
  "children": [
    {
      "id": 9502,
      "label": "paralysis agitans, juvenile, of Hunt",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        11034
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "GARD:0010359",
          "ICD9:333.0",
          "MEDGEN:66768",
          "MESH:C562469",
          "OMIM:168100",
          "SCTID:43647007",
          "UMLS:C0238344"
        ],
        "synonyms": [
          "paralysis agitans, juvenile, of Hunt",
          "Parkinson disease, juvenile, of Hunt"
        ],
        "categories": [
          {
            "ref": "MONDO:0005071",
            "name": "nervous system disorder"
          }
        ]
      },
      "child_count": 0,
      "reference_id": "MONDO:0008193"
    }
  ],
  "roots": [
    {
      "id": 6901,
      "label": "Parkinson disease"
    }
  ]
}