{
  "id": 11154,
  "label": "leukocyte adhesion deficiency type II",
  "model": {
    "label": "Mondo Disease Ontology (MONDO)",
    "source": 0
  },
  "type_id": 0,
  "reference_id": "MONDO:0009953",
  "properties": {
    "xrefs": [
      "DOID:0070255",
      "DOID:0080492",
      "GARD:0004634",
      "MEDGEN:96022",
      "MESH:C535755",
      "NCIT:C4690",
      "OMIM:266265",
      "Orphanet:99843",
      "SCTID:234583001",
      "UMLS:C0398739"
    ],
    "synonyms": [
      "CDG IIc",
      "CDG syndrome type IIc",
      "CDG-IIc",
      "CDG2C",
      "CDGIIc",
      "LAD-II",
      "LAD2",
      "RHS",
      "Rambam-Hasharon syndrome",
      "SLC35C1-CDG",
      "lad-II",
      "lad-type II",
      "leukocyte adhesion deficiency type 2",
      "leukocyte adhesion deficiency type II",
      "leukocyte adhesion deficiency, type II",
      "sialyl-Lewis X defect",
      "CDG 2C",
      "SLC35C1-CDG (CDG-IIc)",
      "congenital disorder of glycosylation type IIC",
      "congenital disorder of glycosylation, type IIc",
      "leukocyte adhesion deficiency, type 2"
    ],
    "categories": [
      {
        "ref": "MONDO:0005046",
        "name": "immune system disorder"
      },
      {
        "ref": "MONDO:0005570",
        "name": "hematologic disorder"
      }
    ],
    "definition": "Leukocyte adhesion deficiency type II (LAD-II) is a form of LAD characterized by recurrent bacterial infections, severe growth delay and severe intellectual deficit."
  },
  "isLeaf": true,
  "isRoot": false,
  "child_count": 0,
  "parents": [
    {
      "id": 7157,
      "label": "congenital disorder of glycosylation type II",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        16168
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:0050571",
          "EFO:0005546",
          "GARD:0024197",
          "MEDGEN:1812737",
          "MESH:C535747",
          "OMIMPS:212066",
          "UMLS:C5574948"
        ],
        "synonyms": [
          "congenital disorder of glycosylation type II",
          "congenital disorders of glycosylation, type II",
          "B4GALT1-CDG",
          "B4GALT1-CDG (CDG-2d)",
          "MGAT2-CDG",
          "MGAT2-CDG (CDG-2a)",
          "MOGS-CDG",
          "MOGS-CDG (CDG-2b)"
        ],
        "definition": "A congenital disorder of glycosylation that involves malfunctioning trimming/processing of the protein-bound oligosaccharide chain."
      },
      "child_count": 26,
      "reference_id": "MONDO:0005501"
    },
    {
      "id": 10564,
      "label": "congenital hematological disorder",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        7217
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "MEDGEN:760584",
          "NCIT:C104003",
          "UMLS:C3267032"
        ],
        "synonyms": [
          "congenital haematological system disease",
          "congenital hematological disorder",
          "congenital hematological system disease"
        ],
        "categories": [
          {
            "ref": "MONDO:0005570",
            "name": "hematologic disorder"
          }
        ],
        "definition": "A disorder of the blood that is present at birth."
      },
      "child_count": 21,
      "reference_id": "MONDO:0009332"
    },
    {
      "id": 17851,
      "label": "leukocyte adhesion deficiency",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        7611,
        16630
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:6612",
          "GARD:0016616",
          "MEDGEN:124419",
          "NANDO:1200355",
          "NANDO:2200755",
          "NCIT:C27874",
          "Orphanet:2968",
          "SCTID:77358003",
          "UMLS:C0272187",
          "icd11.foundation:317341989"
        ],
        "synonyms": [
          "LAD"
        ],
        "categories": [
          {
            "ref": "MONDO:0005046",
            "name": "immune system disorder"
          },
          {
            "ref": "MONDO:0005570",
            "name": "hematologic disorder"
          }
        ],
        "definition": "Leukocyte adhesion deficiency (LAD) is a primary immunodeficiency characterized by defects in the leukocyte adhesion process, marked leukocytosis and recurrent infections."
      },
      "child_count": 6,
      "reference_id": "MONDO:0017570"
    },
    {
      "id": 17978,
      "label": "disorder of multiple glycosylation",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        16168
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "GARD:0021343",
          "MEDGEN:1843364",
          "Orphanet:309526",
          "UMLS:C5681039",
          "icd11.foundation:684473574"
        ]
      },
      "child_count": 19,
      "reference_id": "MONDO:0017749"
    }
  ],
  "children": [],
  "roots": [
    {
      "id": 7157,
      "label": "congenital disorder of glycosylation type II"
    },
    {
      "id": 10564,
      "label": "congenital hematological disorder"
    },
    {
      "id": 17851,
      "label": "leukocyte adhesion deficiency"
    },
    {
      "id": 17978,
      "label": "disorder of multiple glycosylation"
    }
  ]
}