{
  "id": 11190,
  "label": "embryonal rhabdomyosarcoma",
  "model": {
    "label": "Mondo Disease Ontology (MONDO)",
    "source": 0
  },
  "type_id": 0,
  "reference_id": "MONDO:0009993",
  "properties": {
    "xrefs": [
      "DOID:3246",
      "EFO:0000437",
      "GARD:0004702",
      "HP:0006743",
      "ICD9:171.9",
      "ICDO:8910/3",
      "MEDGEN:104910",
      "MedDRA:10065868",
      "NCIT:C8971",
      "OMIM:268210",
      "ONCOTREE:ERMS",
      "Orphanet:99757",
      "SCTID:404051002",
      "UMLS:C0206656"
    ],
    "synonyms": [
      "ERMS",
      "embryonal rhabdomyosarcoma",
      "embryonal rhabdomyosarcoma (disease)",
      "rhabdomyosarcoma, embryonal, type 1",
      "rhabdomyosarcoma, somatic",
      "RMSE1",
      "botryoid rhabdomyosarcoma (type of ERMS)",
      "rhabdomyosarcoma 1",
      "rhabdomyosarcoma chromosomal region",
      "rhabdomyosarcoma embryonal",
      "rhabdomyosarcoma, embryonal, 1",
      "spindle cell rhabdomyosarcomas (type of ERMS)"
    ],
    "definition": "A poorly circumscribed morphologic variant of rhabdomyosarcoma. It is characterized by the presence of primitive skeletal muscle differentiation in any stage of myogenesis."
  },
  "isLeaf": false,
  "isRoot": false,
  "child_count": 5,
  "parents": [
    {
      "id": 6928,
      "label": "rhabdomyosarcoma",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        18239
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:3247",
          "EFO:0002918",
          "GARD:0011951",
          "HP:0002859",
          "ICD9:171.9",
          "ICDO:8900/3",
          "MEDGEN:20561",
          "MESH:D012208",
          "MedDRA:10039022",
          "NANDO:2200056",
          "NCIT:C3359",
          "ONCOTREE:RMS",
          "Orphanet:780",
          "SCTID:302847003",
          "UMLS:C0035412"
        ],
        "synonyms": [
          "rhabdomyosarcoma",
          "rhabdomyosarcoma (disease)",
          "rhabdomyosarcoma, malignant"
        ],
        "definition": "A rare aggressive malignant mesenchymal neoplasm arising from skeletal muscle. It usually occurs in children and young adults. Only a small percentage of tumors arise in the skeletal muscle of the extremities. The majority arise in other anatomical sites."
      },
      "child_count": 20,
      "reference_id": "MONDO:0005212"
    }
  ],
  "children": [
    {
      "id": 3125,
      "label": "parameningeal embryonal rhabdomyosarcoma",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        11190
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:0060338",
          "GARD:0022822"
        ],
        "definition": "An embryonal rhabdomyosarcoma located in the parameningeal region."
      },
      "child_count": 0,
      "reference_id": "MONDO:0000756"
    },
    {
      "id": 4636,
      "label": "prostate embryonal rhabdomyosarcoma",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        7909,
        11190
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:3251",
          "GARD:0023170",
          "MEDGEN:233873",
          "NCIT:C5525",
          "UMLS:C1335508"
        ],
        "synonyms": [
          "embryonal rhabdomyosarcoma (disease) of prostate gland",
          "embryonal rhabdomyosarcoma of prostate",
          "embryonal rhabdomyosarcoma of the prostate",
          "prostate embryonal rhabdomyosarcoma",
          "prostate gland embryonal rhabdomyosarcoma (disease)"
        ],
        "categories": [
          {
            "ref": "MONDO:0005039",
            "name": "reproductive system disorder"
          }
        ],
        "definition": "A malignant mesenchymal neoplasm of the prostate. It is characterized by the presence of skeletal muscle exhibiting embryonic features."
      },
      "child_count": 0,
      "reference_id": "MONDO:0002574"
    },
    {
      "id": 4637,
      "label": "embryonal extrahepatic bile duct rhabdomyosarcoma",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        4638,
        11190
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:3253",
          "GARD:0023171",
          "MEDGEN:234244",
          "NCIT:C5847",
          "UMLS:C1333505"
        ],
        "synonyms": [
          "embryonal extrahepatic bile duct rhabdomyosarcoma",
          "embryonal rhabdomyosarcoma (disease) of extrahepatic bile duct",
          "embryonal rhabdomyosarcoma of extrahepatic bile duct",
          "embryonal rhabdomyosarcoma of the extrahepatic bile duct",
          "extrahepatic bile duct embryonal rhabdomyosarcoma",
          "extrahepatic bile duct embryonal rhabdomyosarcoma (disease)"
        ],
        "categories": [
          {
            "ref": "MONDO:0004335",
            "name": "digestive system disorder"
          },
          {
            "ref": "MONDO:0005151",
            "name": "endocrine system disorder"
          }
        ],
        "definition": "An embryonal rhabdomyosarcoma that arises from the extrahepatic bile ducts."
      },
      "child_count": 0,
      "reference_id": "MONDO:0002576"
    },
    {
      "id": 4639,
      "label": "botryoid rhabdomyosarcoma",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        11190
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:3255",
          "GARD:0009398",
          "ICD9:171.9",
          "MEDGEN:727079",
          "NCIT:C9150",
          "SCTID:404052009",
          "UMLS:C1306574"
        ],
        "synonyms": [
          "botryoid sarcoma",
          "botryoid sarcoma (morphologic abnormality)",
          "botryoid-type embryonal rhabdomyosarcoma",
          "sarcoma botryoides"
        ],
        "definition": "A morphologic variant of embryonal rhabdomyosarcoma arising from organs with a mucosal epithelial surface. It is characterized by the formation of a cambium layer in the affected tissue and polypoid nodules within an abundant myxoid stroma."
      },
      "child_count": 3,
      "reference_id": "MONDO:0002578"
    },
    {
      "id": 4640,
      "label": "orbit embryonal rhabdomyosarcoma",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        4641,
        11190
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:3258",
          "GARD:0023173",
          "MEDGEN:233267",
          "NCIT:C6246",
          "UMLS:C1335127"
        ],
        "synonyms": [
          "embryonal rhabdomyosarcoma of orbit",
          "embryonal rhabdomyosarcoma of the orbit"
        ],
        "categories": [
          {
            "ref": "MONDO:0002022",
            "name": "disorder of orbital region"
          },
          {
            "ref": "MONDO:0002081",
            "name": "musculoskeletal system disorder"
          },
          {
            "ref": "MONDO:0003900",
            "name": "connective tissue disorder"
          }
        ],
        "definition": "A malignant mesenchymal neoplasm that arises from the orbit. It is characterized by the presence of skeletal muscle tissue exhibiting embryonic features."
      },
      "child_count": 0,
      "reference_id": "MONDO:0002579"
    }
  ],
  "roots": [
    {
      "id": 6928,
      "label": "rhabdomyosarcoma"
    }
  ]
}