{
  "id": 11224,
  "label": "Sjogren syndrome",
  "model": {
    "label": "Mondo Disease Ontology (MONDO)",
    "source": 0
  },
  "type_id": 0,
  "reference_id": "MONDO:0010030",
  "properties": {
    "xrefs": [
      "DOID:12894",
      "EFO:0000699",
      "ICD10CM:M35.0",
      "ICD9:710.2",
      "MEDGEN:282890",
      "MESH:D012859",
      "NANDO:1200279",
      "NANDO:1200280",
      "NANDO:2200420",
      "NCIT:C26883",
      "OMIM:270150",
      "Orphanet:289390",
      "Orphanet:378",
      "SCTID:83901003",
      "UMLS:C1527336",
      "icd11.foundation:899463360"
    ],
    "synonyms": [
      "Sjogren syndrome",
      "Sjögren syndrome",
      "Sjögren-Gougerot syndrome",
      "primary Sjogren-Gougerot syndrome",
      "primary Sjögren-Gougerot syndrome",
      "sicca syndrome",
      "syndrome, Sjogren's",
      "Sjogren's syndrome",
      "primary Sjögren syndrome"
    ],
    "categories": [
      {
        "ref": "MONDO:0002022",
        "name": "disorder of orbital region"
      },
      {
        "ref": "MONDO:0002254",
        "name": "syndromic disease"
      },
      {
        "ref": "MONDO:0005046",
        "name": "immune system disorder"
      },
      {
        "ref": "MONDO:0006858",
        "name": "mouth disorder"
      },
      {
        "ref": "MONDO:0024458",
        "name": "disorder of visual system"
      }
    ],
    "definition": "An autoimmune disorder in which immune cells attack and destroy the glands that produce tears and saliva. Sjögren syndrome is also associated with rheumatic disorders such as rheumatoid arthritis or systemic lupus erythematosus. The hallmark symptoms of Sjögren syndrome are dry mouth and dry eyes. In addition, Sjogren syndrome may cause skin, nose, and vaginal dryness. It also may affect other organs of the body including the kidneys, blood vessels, lungs, liver, pancreas, and brain"
  },
  "isLeaf": true,
  "isRoot": false,
  "child_count": 0,
  "parents": [
    {
      "id": 3002,
      "label": "autoimmune disorder of exocrine system",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        8586
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:0060029"
        ],
        "synonyms": [
          "exocrine system autoimmune disease",
          "exocrine system hypersensitivity reaction type II disease"
        ],
        "categories": [
          {
            "ref": "MONDO:0005046",
            "name": "immune system disorder"
          }
        ],
        "definition": "A hypersensitivity reaction type II disease that involves the exocrine system."
      },
      "child_count": 3,
      "reference_id": "MONDO:0000586"
    },
    {
      "id": 3387,
      "label": "salivary gland disorder",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        8301
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:10854",
          "EFO:0008581",
          "ICD9:527.8",
          "ICD9:527.9",
          "MEDGEN:892384",
          "MESH:D012466",
          "NCIT:C26879",
          "SCTID:10890000",
          "UMLS:C0149772",
          "icd11.foundation:1432273670"
        ],
        "synonyms": [
          "disease of saliva-secreting gland",
          "disease or disorder of saliva-secreting gland",
          "disorder of saliva-secreting gland",
          "saliva-secreting gland disease",
          "saliva-secreting gland disease or disorder",
          "salivary gland disease",
          "salivary gland disorder",
          "non-neoplastic salivary gland disease"
        ],
        "categories": [
          {
            "ref": "MONDO:0006858",
            "name": "mouth disorder"
          }
        ],
        "definition": "A disease involving the saliva-secreting gland."
      },
      "child_count": 9,
      "reference_id": "MONDO:0001142"
    },
    {
      "id": 4370,
      "label": "syndromic disease",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        29379
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:225",
          "MEDGEN:11688",
          "MESH:D013577",
          "NCIT:C28193",
          "OGMS:0000086",
          "UMLS:C0039082"
        ],
        "synonyms": [
          "cluster, symptom",
          "clusters, symptom",
          "symptom cluster",
          "symptom clusters",
          "syndrome",
          "syndrome associated with disease or disorder",
          "syndromes",
          "syndromic disease",
          "syndromic disease or disorder"
        ],
        "categories": [
          {
            "ref": "MONDO:0002254",
            "name": "syndromic disease"
          }
        ],
        "definition": "A group of signs, symptoms, and clinicopathological characteristics that may or may not have a genetic basis and collectively define an abnormal condition."
      },
      "child_count": 1182,
      "reference_id": "MONDO:0002254"
    },
    {
      "id": 21539,
      "label": "disorder of lacrimal gland",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        4032
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "MEDGEN:536365",
          "SCTID:95766002",
          "UMLS:C0235228"
        ],
        "synonyms": [
          "disease of lacrimal gland",
          "disease or disorder of lacrimal gland",
          "disorder of lacrimal gland",
          "lacrimal gland disease",
          "lacrimal gland disease or disorder"
        ],
        "categories": [
          {
            "ref": "MONDO:0002022",
            "name": "disorder of orbital region"
          },
          {
            "ref": "MONDO:0024458",
            "name": "disorder of visual system"
          }
        ],
        "definition": "A disease that involves the lacrimal gland."
      },
      "child_count": 4,
      "reference_id": "MONDO:0024625"
    }
  ],
  "children": [],
  "roots": [
    {
      "id": 3002,
      "label": "autoimmune disorder of exocrine system"
    },
    {
      "id": 3387,
      "label": "salivary gland disorder"
    },
    {
      "id": 4370,
      "label": "syndromic disease"
    },
    {
      "id": 21539,
      "label": "disorder of lacrimal gland"
    }
  ]
}