{
  "id": 11361,
  "label": "isolated right ventricular hypoplasia",
  "model": {
    "label": "Mondo Disease Ontology (MONDO)",
    "source": 0
  },
  "type_id": 0,
  "reference_id": "MONDO:0010179",
  "properties": {
    "xrefs": [
      "GARD:0004721",
      "MEDGEN:336377",
      "MESH:C535682",
      "OMIM:277200",
      "Orphanet:439",
      "SCTID:718135001",
      "UMLS:C1848587"
    ],
    "synonyms": [
      "Irvh",
      "hypoplasia of the right ventricle",
      "isolated hypoplasia of the right ventricle",
      "right ventricle hypoplasia",
      "right ventricular hypoplasia",
      "right ventricular hypoplasia, isolated"
    ],
    "categories": [
      {
        "ref": "MONDO:0002254",
        "name": "syndromic disease"
      },
      {
        "ref": "MONDO:0004995",
        "name": "cardiovascular disorder"
      }
    ],
    "definition": "Isolated right ventricular hypoplasia (IRVH) is a rare congenital heart malformation characterized by underdevelopment of the right ventricle associated with patent foramen ovale or interauricular communication and normally developed tricuspid and pulmonary valves. IRVH manifests with severe cyanosis, congestive heart failure, and in severe cases, death in early infancy."
  },
  "isLeaf": true,
  "isRoot": false,
  "child_count": 0,
  "parents": [
    {
      "id": 5714,
      "label": "hereditary disease",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        29382
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:630",
          "EFO:0000508",
          "ICD9:799.89",
          "MEDGEN:5527",
          "MESH:D030342",
          "NCIT:C3101",
          "SCTID:32895009",
          "UMLS:C0019247"
        ],
        "synonyms": [
          "genetic condition",
          "genetic disease",
          "genetic disorder",
          "hereditary disease",
          "hereditary disease or disorder",
          "hereditary diseases",
          "inherited disease",
          "inherited genetic disease",
          "molecular disease",
          "Mendelian disease",
          "familial disorder",
          "inborn disorder"
        ],
        "definition": "A disease that is caused by genetic modifications where those modifications are inherited from a parent's genome."
      },
      "child_count": 1925,
      "reference_id": "MONDO:0003847"
    },
    {
      "id": 19776,
      "label": "hypoplastic right heart syndrome",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        4370,
        19559
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:0070315",
          "GARD:0002922",
          "ICD10CM:Q22.6",
          "ICD9:746.89",
          "MEDGEN:83376",
          "MedDRA:10050053",
          "MedDRA:10064962",
          "NCIT:C99053",
          "Orphanet:98723",
          "SCTID:268180007",
          "UMLS:C0344963"
        ],
        "synonyms": [
          "right hypoplastic heart syndrome"
        ],
        "categories": [
          {
            "ref": "MONDO:0002254",
            "name": "syndromic disease"
          },
          {
            "ref": "MONDO:0004995",
            "name": "cardiovascular disorder"
          }
        ],
        "definition": "Hypoplastic right-heart syndrome (HRHS) is a rare, cyanotic congenital heart malformation caused by underdevelopment of the right-sided heart structures (tricuspid valve, RV, pulmonary valve, and pulmonary artery) commonly associated with an atrial septal defect, ostium secundum type. Pulmonary blood flow is diminished and right-to-left shunting occurs at the atrial level, leading to dyspnea, fatigue, atrial arrhythmias, right-sided heart failure, hypoxemia, repeated miscarriages that were mostly due to hypoxemia and cyanosis. Two subtypes of HRHS have been characterized: pulmonary atresia-intact ventricular septum and right ventricular hypoplasia."
      },
      "child_count": 4,
      "reference_id": "MONDO:0020291"
    }
  ],
  "children": [],
  "roots": [
    {
      "id": 5714,
      "label": "hereditary disease"
    },
    {
      "id": 19776,
      "label": "hypoplastic right heart syndrome"
    }
  ]
}