{
  "id": 11579,
  "label": "hereditary spastic paraplegia 34",
  "model": {
    "label": "Mondo Disease Ontology (MONDO)",
    "source": 0
  },
  "type_id": 0,
  "reference_id": "MONDO:0010418",
  "properties": {
    "xrefs": [
      "DOID:0110785",
      "GARD:0017063",
      "MEDGEN:437069",
      "MESH:C567465",
      "OMIM:300750",
      "Orphanet:171607",
      "SCTID:763370008",
      "UMLS:C2677897"
    ],
    "synonyms": [
      "SPG34",
      "X-linked spastic paraplegia type 34",
      "hereditary spastic paraplegia type 34",
      "spastic paraplegia 34, X-linked, X-linked recessive",
      "spastic paraplegia 34, X-linked"
    ],
    "categories": [
      {
        "ref": "MONDO:0005071",
        "name": "nervous system disorder"
      }
    ],
    "definition": "X-linked spastic paraplegia type 34 is a pure form of hereditary spastic paraplegia characterized by late childhood- to early adulthood-onset of slowly progressive spastic paraplegia with spastic gait and lower limb hyperreflexia, brisk tendon reflexes and ankle clonus. Lower limb pain and reduced lower limb vibratory sense is also reported in some older adult patients."
  },
  "isLeaf": true,
  "isRoot": false,
  "child_count": 0,
  "parents": [
    {
      "id": 16081,
      "label": "pure hereditary spastic paraplegia",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        18959
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "GARD:0019822",
          "MEDGEN:581445",
          "NANDO:1200053",
          "Orphanet:102012",
          "SCTID:230260007",
          "UMLS:C0393555"
        ],
        "synonyms": [
          "Pure HSP",
          "Pure SPG",
          "Pure familial spastic paraplegia",
          "uncomplicated HSP",
          "uncomplicated SPG",
          "uncomplicated familial spastic paraplegia",
          "uncomplicated hereditary spastic paraplegia"
        ],
        "categories": [
          {
            "ref": "MONDO:0005071",
            "name": "nervous system disorder"
          }
        ]
      },
      "child_count": 12,
      "reference_id": "MONDO:0015149"
    }
  ],
  "children": [],
  "roots": [
    {
      "id": 16081,
      "label": "pure hereditary spastic paraplegia"
    }
  ]
}