{
  "id": 11594,
  "label": "synovial sarcoma",
  "model": {
    "label": "Mondo Disease Ontology (MONDO)",
    "source": 0
  },
  "type_id": 0,
  "reference_id": "MONDO:0010434",
  "properties": {
    "xrefs": [
      "DOID:5485",
      "EFO:0001376",
      "GARD:0007721",
      "HP:0012570",
      "ICD9:171.9",
      "ICDO:9040/3",
      "MEDGEN:21050",
      "MESH:D013584",
      "MedDRA:10042863",
      "NANDO:2200061",
      "NCIT:C3400",
      "OMIM:300813",
      "ONCOTREE:SYNS",
      "Orphanet:3273",
      "SCTID:302851001",
      "UMLS:C0039101"
    ],
    "synonyms": [
      "SS",
      "Synovialosarcoma",
      "sarcoma, synovial, malignant",
      "synovial sarcoma",
      "synovial sarcoma (disease)",
      "sarcoma, synovial"
    ],
    "definition": "Synovial sarcoma is an aggressive soft tissue sarcoma, occurring most commonly in adolescents and young adults (15 to 40 years), usually localized near the large joints of the extremities but also in the head and neck, mediastinum and viscera (lung, kidney etc), clinically presenting as a deep seated swelling or a painful mass often with an initial indolent course and is characterized by its local invasiveness and a propensity to metastasize. The origin of synovial sarcoma is likely from multipotent mesenchymal cells and not synovium (contrary to its name)."
  },
  "isLeaf": false,
  "isRoot": false,
  "child_count": 5,
  "parents": [
    {
      "id": 5714,
      "label": "hereditary disease",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        29382
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:630",
          "EFO:0000508",
          "ICD9:799.89",
          "MEDGEN:5527",
          "MESH:D030342",
          "NCIT:C3101",
          "SCTID:32895009",
          "UMLS:C0019247"
        ],
        "synonyms": [
          "genetic condition",
          "genetic disease",
          "genetic disorder",
          "hereditary disease",
          "hereditary disease or disorder",
          "hereditary diseases",
          "inherited disease",
          "inherited genetic disease",
          "molecular disease",
          "Mendelian disease",
          "familial disorder",
          "inborn disorder"
        ],
        "definition": "A disease that is caused by genetic modifications where those modifications are inherited from a parent's genome."
      },
      "child_count": 1925,
      "reference_id": "MONDO:0003847"
    },
    {
      "id": 18239,
      "label": "soft tissue sarcoma",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        6816,
        21548
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:0070663",
          "EFO:1001968",
          "GARD:0004898",
          "MEDGEN:1642116",
          "NCIT:C9306",
          "NORD:1953",
          "Orphanet:3394",
          "SCTID:424952003",
          "UMLS:C4551687"
        ],
        "synonyms": [
          "malignant soft tissue tumor",
          "malignant soft tissue tumour",
          "connective tissue sarcoma",
          "malignant mesenchymal tumor",
          "malignant mesenchymal tumour",
          "non-Rhabdo. soft tissue sarcoma",
          "sarcoma of soft tissue",
          "sarcoma of the soft tissue",
          "soft part sarcoma",
          "soft tissue sarcoma"
        ],
        "definition": "A malignant neoplasm arising from muscle tissue, adipose tissue, blood vessels, fibrous tissue, or other supportive tissues excluding the bones."
      },
      "child_count": 92,
      "reference_id": "MONDO:0018078"
    }
  ],
  "children": [
    {
      "id": 5387,
      "label": "fibrous synovial sarcoma",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        11594
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:5484",
          "GARD:0023512",
          "MEDGEN:234267",
          "NCIT:C6533",
          "UMLS:C1333616"
        ],
        "synonyms": [
          "fibrous sarcoma of the synovium"
        ]
      },
      "child_count": 0,
      "reference_id": "MONDO:0003465"
    },
    {
      "id": 5389,
      "label": "mediastinum synovial sarcoma",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        4866,
        11594
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:5488",
          "GARD:0023514",
          "MEDGEN:233174",
          "NCIT:C6618",
          "UMLS:C1334681"
        ],
        "synonyms": [
          "mediastinal synovial sarcoma",
          "mediastinum synovial sarcoma (disease)",
          "synovial sarcoma of mediastinum",
          "synovial sarcoma of the mediastinum"
        ],
        "definition": "A synovial sarcoma arising from the mediastinum."
      },
      "child_count": 0,
      "reference_id": "MONDO:0003467"
    },
    {
      "id": 5390,
      "label": "biphasic synovial sarcoma",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        11594
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:5492",
          "GARD:0023515",
          "ICDO:9043/3",
          "MEDGEN:137773",
          "NCIT:C4279",
          "UMLS:C0334507"
        ],
        "synonyms": [
          "biphasic sarcoma of synovium",
          "biphasic sarcoma of the synovium",
          "synovial sarcoma, biphasic (morphologic abnormality)"
        ],
        "definition": "A synovial sarcoma characterized by the presence of both an epithelial and a spindle cell component."
      },
      "child_count": 0,
      "reference_id": "MONDO:0003468"
    },
    {
      "id": 6796,
      "label": "monophasic synovial sarcoma",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        11594
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:5495",
          "EFO:0000595",
          "GARD:0024147",
          "MEDGEN:233719",
          "NCIT:C6534",
          "UMLS:C1334801"
        ],
        "synonyms": [
          "monophasic sarcoma of synovium",
          "monophasic sarcoma of the synovium",
          "monophasic synovial sarcoma"
        ],
        "definition": "A synovial sarcoma characterized by the presence of an epithelial or a spindle cell component only."
      },
      "child_count": 2,
      "reference_id": "MONDO:0005067"
    },
    {
      "id": 7613,
      "label": "breast synovial sarcoma",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        4569,
        11594
      ],
      "type_id": 0,
      "properties": {
        "synonyms": [
          "breast synovial sarcoma (disease)"
        ],
        "categories": [
          {
            "ref": "MONDO:0002657",
            "name": "breast disorder"
          }
        ],
        "definition": "A synovial sarcoma (disease) that involves the breast."
      },
      "child_count": 0,
      "reference_id": "MONDO:0006027"
    }
  ],
  "roots": [
    {
      "id": 5714,
      "label": "hereditary disease"
    },
    {
      "id": 18239,
      "label": "soft tissue sarcoma"
    }
  ]
}