{
  "id": 11848,
  "label": "premature ovarian failure 1",
  "model": {
    "label": "Mondo Disease Ontology (MONDO)",
    "source": 0
  },
  "type_id": 0,
  "reference_id": "MONDO:0010706",
  "properties": {
    "xrefs": [
      "DOID:0080857",
      "GARD:0002811",
      "ICD9:256.39",
      "MEDGEN:1644269",
      "OMIM:311360",
      "Orphanet:642691",
      "UMLS:C4552079"
    ],
    "synonyms": [
      "ovarian failure, premature",
      "FMR1 primary ovarian failure",
      "fragile x-associated primary ovarian insufficiency",
      "premature ovarian failure 1",
      "premature ovarian failure type 1",
      "primary ovarian failure caused by mutation in FMR1",
      "FMR1-related premature ovarian failure",
      "FMR1-related primary ovarian insufficiency",
      "Pof1",
      "familial premature ovarian failure",
      "fragile X-associated primary ovarian insufficiency",
      "hypergonadotropic ovarian failure, X-linked",
      "idiopathic familial premature ovarian failure",
      "premature ovarian failure, X-linked"
    ],
    "categories": [
      {
        "ref": "MONDO:0005039",
        "name": "reproductive system disorder"
      },
      {
        "ref": "MONDO:0005151",
        "name": "endocrine system disorder"
      }
    ],
    "definition": "Any primary ovarian failure in which the cause of the disease is a mutation in the FMR1 gene."
  },
  "isLeaf": false,
  "isRoot": false,
  "child_count": 1,
  "parents": [
    {
      "id": 19578,
      "label": "inherited primary ovarian failure",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        5714,
        7067,
        16330,
        20362
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "GARD:0019294",
          "MEDGEN:443920",
          "OMIMPS:311360",
          "Orphanet:95710",
          "UMLS:C2930861"
        ],
        "synonyms": [
          "hereditary primary ovarian failure",
          "inherited POI",
          "inherited premature ovarian failure",
          "inherited primary ovarian insufficiency",
          "non-acquired premature ovarian failure"
        ],
        "categories": [
          {
            "ref": "MONDO:0005039",
            "name": "reproductive system disorder"
          },
          {
            "ref": "MONDO:0005151",
            "name": "endocrine system disorder"
          }
        ],
        "definition": "An instance of primary ovarian failure that is caused by an inherited modification of the individual's genome."
      },
      "child_count": 164,
      "reference_id": "MONDO:0019852"
    }
  ],
  "children": [
    {
      "id": 18661,
      "label": "symptomatic form of fragile X syndrome in female carrier",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        11546,
        11848
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "GARD:0017783",
          "MEDGEN:1814467",
          "Orphanet:449291",
          "UMLS:C5681104"
        ],
        "categories": [
          {
            "ref": "MONDO:0002254",
            "name": "syndromic disease"
          },
          {
            "ref": "MONDO:0005039",
            "name": "reproductive system disorder"
          },
          {
            "ref": "MONDO:0005151",
            "name": "endocrine system disorder"
          }
        ]
      },
      "child_count": 0,
      "reference_id": "MONDO:0018670"
    }
  ],
  "roots": [
    {
      "id": 19578,
      "label": "inherited primary ovarian failure"
    }
  ]
}