{
  "id": 11936,
  "label": "deafness, aminoglycoside-induced",
  "model": {
    "label": "Mondo Disease Ontology (MONDO)",
    "source": 0
  },
  "type_id": 0,
  "reference_id": "MONDO:0010799",
  "properties": {
    "xrefs": [
      "DOID:0111734",
      "GARD:0018161",
      "MEDGEN:374074",
      "MESH:C564013",
      "OMIM:580000",
      "Orphanet:168609",
      "UMLS:C1838854"
    ],
    "synonyms": [
      "aminoglycoside-induced hearing loss",
      "mitochondrial isolated neurosensory hearing loss with susceptibility to aminoglycoside exposure",
      "mitochondrial isolated sensorineural hearing loss with susceptibility to aminoglycoside exposure",
      "mitochondrial non-syndromic neurosensory hearing loss with susceptibility to aminoglycoside exposure",
      "mitochondrial non-syndromic sensorineural hearing loss with susceptibility to aminoglycoside exposure",
      "deafness, aminoglycoside-induced",
      "deafness, mitochondrial, modifier of, mitochondrial",
      "deafness, streptomycin-induced",
      "mitochondrial isolated neurosensory deafness with susceptibility to aminoglycoside exposure",
      "mitochondrial isolated sensorineural deafness with susceptibility to aminoglycoside exposure",
      "mitochondrial non-syndromic neurosensory deafness with susceptibility to aminoglycoside exposure",
      "mitochondrial non-syndromic sensorineural deafness with susceptibility to aminoglycoside exposure",
      "streptomycin ototoxicity"
    ],
    "categories": [
      {
        "ref": "MONDO:0002409",
        "name": "auditory system disorder"
      },
      {
        "ref": "MONDO:0005071",
        "name": "nervous system disorder"
      }
    ]
  },
  "isLeaf": true,
  "isRoot": false,
  "child_count": 0,
  "parents": [
    {
      "id": 16854,
      "label": "postlingual non-syndromic genetic hearing loss",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        19315
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "GARD:0025070",
          "MEDGEN:1641874",
          "Orphanet:216452",
          "SCTID:764097002",
          "UMLS:C4706678"
        ],
        "synonyms": [
          "isolated postlingual genetic deafness",
          "postlingual non-syndromic genetic deafness"
        ],
        "categories": [
          {
            "ref": "MONDO:0002409",
            "name": "auditory system disorder"
          },
          {
            "ref": "MONDO:0005071",
            "name": "nervous system disorder"
          }
        ],
        "definition": "Postlingual non-syndromic genetic deafness is a rare, genetically highly heterogeneous otorhinolaryngologic disease, resulting from inner and/or middle ear or hearing nerve anomalies, typically characterized by progressive, bilateral, moderate to profound hearing loss (mean sensorineural hearing impairment equal to 40 dB or more for 500-, 1,000-, and 2,000-Hz frequency tones in the better ear) which occurs after the onset of speech development and is not associated with visible external ear abnormalities or any other medical problems. Language development is not initially significantly delayed."
      },
      "child_count": 1,
      "reference_id": "MONDO:0016298"
    },
    {
      "id": 16918,
      "label": "mitochondrial oxidative phosphorylation disorder",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        5908
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "GARD:0020546",
          "MEDGEN:1825947",
          "Orphanet:223713",
          "UMLS:C5679825",
          "icd11.foundation:1204111545"
        ],
        "synonyms": [
          "OXPHOS disease",
          "OXPHOS system deficiency"
        ],
        "definition": "A multisystem disorder with variable manifestations resulting from a defect in the mitochondrial oxidative phosphorylation (OXPHOS) system."
      },
      "child_count": 48,
      "reference_id": "MONDO:0016387"
    }
  ],
  "children": [],
  "roots": [
    {
      "id": 16854,
      "label": "postlingual non-syndromic genetic hearing loss"
    },
    {
      "id": 16918,
      "label": "mitochondrial oxidative phosphorylation disorder"
    }
  ]
}