{
  "id": 11992,
  "label": "semantic dementia",
  "model": {
    "label": "Mondo Disease Ontology (MONDO)",
    "source": 0
  },
  "type_id": 0,
  "reference_id": "MONDO:0010857",
  "properties": {
    "xrefs": [
      "DOID:0051060",
      "DOID:0081391",
      "GARD:0010792",
      "MEDGEN:83268",
      "NANDO:1200550",
      "OMIM:600274",
      "Orphanet:100069",
      "UMLS:C0338462"
    ],
    "synonyms": [
      "dementia, frontotemporal",
      "dementia, frontotemporal, with or without parkinsonism",
      "semantic primary progressive aphasia",
      "semantic variant PPA",
      "FTD",
      "Ftdp17",
      "Ftld with Tau inclusions",
      "Pallidopontonigral Degeneration",
      "Pick Complex",
      "Wilhelmsen-Lynch disease",
      "dementia, frontotemporal, with Parkinsonism",
      "disinhibition-dementia-Parkinsonism-amyotrophy Complex",
      "frontotemporal dementia",
      "frontotemporal dementia with Parkinsonism",
      "frontotemporal lobar Degeneration with Tau inclusions",
      "frontotemporal lobe dementia",
      "multiple system tauopathy with presenile dementia"
    ],
    "categories": [
      {
        "ref": "MONDO:0005071",
        "name": "nervous system disorder"
      }
    ],
    "definition": "Semantic dementia (SD) is a form of frontotemporal dementia (FTD), characterized by the progressive, amodal and profound loss of semantic knowledge (combination of visual associative agnosia, anomia, surface dyslexia or dysgraphia and disrupted comprehension of word meaning) and behavioral abnormalities, attributable to the degeneration of the anterior temporal lobes."
  },
  "isLeaf": false,
  "isRoot": false,
  "child_count": 1,
  "parents": [
    {
      "id": 16033,
      "label": "progressive non-fluent aphasia",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        7073,
        12923
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:0081390",
          "GARD:0010793",
          "MEDGEN:148373",
          "MESH:D057178",
          "MedDRA:10029542",
          "NCIT:C85025",
          "Orphanet:100070",
          "SCTID:716281000",
          "UMLS:C0751706"
        ],
        "synonyms": [
          "Agramatic variant of PPA",
          "Agramatic variant of primary progressive aphasia",
          "Primary Progressive Nonfluent aphasia",
          "non-fluent variant PPA",
          "non-fluent primary progressive aphasia"
        ],
        "categories": [
          {
            "ref": "MONDO:0005071",
            "name": "nervous system disorder"
          }
        ],
        "definition": "Progressive non-fluent aphasia (PNFA) is a form of frontotemporal dementia (FTD), characterized by agrammatism, laborious speech, alexia, and agraphia, frequently accompanied by apraxia of speech (AOS). Language comprehension is relatively preserved."
      },
      "child_count": 2,
      "reference_id": "MONDO:0015059"
    },
    {
      "id": 17505,
      "label": "behavioral variant of frontotemporal dementia",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        7073,
        17600
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "GARD:0007392",
          "MEDGEN:860225",
          "NANDO:1200549",
          "Orphanet:275864",
          "SCTID:716994006",
          "UMLS:C4011788"
        ],
        "synonyms": [
          "bv-FTD"
        ],
        "categories": [
          {
            "ref": "MONDO:0005071",
            "name": "nervous system disorder"
          }
        ],
        "definition": "Behavioral variant of frontotemporal dementia (bv-FTD) is a form of frontotemporal dementia (FTD), characterized by progressive behavioral impairment and a decline in executive function with frontal lobe-predominant atrophy."
      },
      "child_count": 6,
      "reference_id": "MONDO:0017160"
    }
  ],
  "children": [
    {
      "id": 17706,
      "label": "frontotemporal dementia, right temporal atrophy variant",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        11992
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "GARD:0025093",
          "Orphanet:293848",
          "SCTID:716667005"
        ],
        "synonyms": [
          "RTLA",
          "rvFTD"
        ],
        "categories": [
          {
            "ref": "MONDO:0005071",
            "name": "nervous system disorder"
          }
        ],
        "definition": "Right temporal lobar atrophy (RTLA) is an anatomic variant of frontotemporal dementia (FTD), characterized by behavioral dysfunction, personality changes, episodic memory loss, and prosopagnosia; attributable to an asymmetrical predominantly right-sided, frontotemporal atrophy."
      },
      "child_count": 0,
      "reference_id": "MONDO:0017399"
    }
  ],
  "roots": [
    {
      "id": 16033,
      "label": "progressive non-fluent aphasia"
    },
    {
      "id": 17505,
      "label": "behavioral variant of frontotemporal dementia"
    }
  ]
}