{
  "id": 12041,
  "label": "loose anagen syndrome",
  "model": {
    "label": "Mondo Disease Ontology (MONDO)",
    "source": 0
  },
  "type_id": 0,
  "reference_id": "MONDO:0010908",
  "properties": {
    "xrefs": [
      "DOID:0111702",
      "GARD:0003287",
      "ICD9:704.8",
      "MEDGEN:98351",
      "MESH:D058247",
      "OMIM:600628",
      "Orphanet:168",
      "SCTID:238735005",
      "UMLS:C0406468",
      "icd11.foundation:547259783"
    ],
    "synonyms": [
      "loose anagen hair syndrome"
    ],
    "categories": [
      {
        "ref": "MONDO:0002051",
        "name": "integumentary system disorder"
      }
    ],
    "definition": "Loose anagen syndrome is a rare benign hair disorder affecting predominantly blond females in childhood and characterized by the presence of hair that can be easily and painlessly pulled out. Most of the hair is in the anagen phase and lacks an external epithelial sheath. Hair grows back quickly and the condition improves spontaneously with aging. Loose anagen hair can be associated with other anomalies, such as coloboma."
  },
  "isLeaf": false,
  "isRoot": false,
  "child_count": 1,
  "parents": [
    {
      "id": 6660,
      "label": "alopecia",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        19134
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:987",
          "ICD9:704.0",
          "ICD9:704.00",
          "ICD9:704.09",
          "MEDGEN:7982",
          "MESH:D000505",
          "NCIT:C50575",
          "Orphanet:79364",
          "SCTID:56317004",
          "UMLS:C0002170",
          "icd11.foundation:1313926062"
        ],
        "synonyms": [
          "alopecia",
          "hair loss",
          "loss Of hair",
          "alopecia areata"
        ],
        "categories": [
          {
            "ref": "MONDO:0002051",
            "name": "integumentary system disorder"
          }
        ],
        "definition": "Hair loss usually from the scalp. It may result in bald spots or spread to the entire scalp or the entire epidermis. It may be androgenetic or caused by chemotherapeutic agents, compulsive hair pulling, autoimmune disorders or congenital conditions."
      },
      "child_count": 26,
      "reference_id": "MONDO:0004907"
    },
    {
      "id": 20383,
      "label": "disorder of development or morphogenesis",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        29380
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "ICD10CM:Q00-Q99",
          "MEDGEN:1843482",
          "UMLS:C0694457"
        ],
        "definition": "Any disease or disorder that disrupts the process development of an anatomical structure. Can be due to genetic or environmental causes. Typically happens during embryogenesis, but also includes post-embryonic development."
      },
      "child_count": 190,
      "reference_id": "MONDO:0021147"
    }
  ],
  "children": [
    {
      "id": 12975,
      "label": "Noonan syndrome-like disorder with loose anagen hair",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        12041,
        16088,
        19780
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:0080691",
          "GARD:0010719",
          "MEDGEN:334697",
          "MESH:C564342",
          "NCIT:C178129",
          "OMIMPS:607721",
          "Orphanet:2701",
          "SCTID:723444009",
          "UMLS:C1843181"
        ],
        "synonyms": [
          "NS/LAH",
          "Noonan syndrome-like disorder with loose anagen hair",
          "Tosti syndrome",
          "NSLH",
          "NSLH1",
          "Noonan syndrome-like disorder with loose anagen hair 1",
          "Noonan-like syndrome with loose anagen hair"
        ],
        "categories": [
          {
            "ref": "MONDO:0002051",
            "name": "integumentary system disorder"
          },
          {
            "ref": "MONDO:0002081",
            "name": "musculoskeletal system disorder"
          },
          {
            "ref": "MONDO:0004995",
            "name": "cardiovascular disorder"
          }
        ],
        "definition": "Noonan-like syndrome with loose anagen hair (NS/LAH) is a Noonan-related syndrome, characterized by facial anomalies suggestive of Noonan syndrome ; a distinctive hair anomaly described as loose anagen hair syndrome ; frequent congenital heart defects; distinctive skin features with darkly pigmented skin, keratosis pilaris, eczema or occasional neonatal ichtyosis ; and short stature, often associated with a GH deficiency and psychomotor delays."
      },
      "child_count": 6,
      "reference_id": "MONDO:0011899"
    }
  ],
  "roots": [
    {
      "id": 6660,
      "label": "alopecia"
    },
    {
      "id": 20383,
      "label": "disorder of development or morphogenesis"
    }
  ]
}