{
  "id": 12067,
  "label": "frontotemporal dementia and/or amyotrophic lateral sclerosis 7",
  "model": {
    "label": "Mondo Disease Ontology (MONDO)",
    "source": 0
  },
  "type_id": 0,
  "reference_id": "MONDO:0010936",
  "properties": {
    "xrefs": [
      "DOID:0060208",
      "DOID:0111227",
      "GARD:0015322",
      "ICD9:331.19",
      "MEDGEN:318833",
      "MESH:C563708",
      "MESH:C579991",
      "OMIM:600795",
      "OMIM:614696",
      "SCTID:702393003",
      "UMLS:C1833296"
    ],
    "synonyms": [
      "CHMP2B amyotrophic lateral sclerosis",
      "CHMP2B-related amyotrophic lateral sclerosis",
      "FTD3",
      "amyotrophic lateral sclerosis caused by mutation in CHMP2B",
      "amyotrophic lateral sclerosis, Chmp2B-related",
      "frontotemporal dementia, chromosome 3-linked",
      "Dmt1",
      "dementia, familial nonspecific"
    ],
    "categories": [
      {
        "ref": "MONDO:0005071",
        "name": "nervous system disorder"
      }
    ],
    "definition": "Any amyotrophic lateral sclerosis in which the cause of the disease is a mutation in the CHMP2B gene."
  },
  "isLeaf": true,
  "isRoot": false,
  "child_count": 0,
  "parents": [
    {
      "id": 6868,
      "label": "familial amyotrophic lateral sclerosis",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        6718,
        21302
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "EFO:0001356",
          "GARD:0024155",
          "MEDGEN:1642547",
          "OMIMPS:105400",
          "UMLS:C4551993"
        ],
        "synonyms": [
          "hereditary amyotrophic lateral sclerosis"
        ],
        "categories": [
          {
            "ref": "MONDO:0005071",
            "name": "nervous system disorder"
          }
        ],
        "definition": "An instance of amyotrophic lateral sclerosis that is caused by an inherited modification of the individual's genome."
      },
      "child_count": 60,
      "reference_id": "MONDO:0005144"
    },
    {
      "id": 17505,
      "label": "behavioral variant of frontotemporal dementia",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        7073,
        17600
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "GARD:0007392",
          "MEDGEN:860225",
          "NANDO:1200549",
          "Orphanet:275864",
          "SCTID:716994006",
          "UMLS:C4011788"
        ],
        "synonyms": [
          "bv-FTD"
        ],
        "categories": [
          {
            "ref": "MONDO:0005071",
            "name": "nervous system disorder"
          }
        ],
        "definition": "Behavioral variant of frontotemporal dementia (bv-FTD) is a form of frontotemporal dementia (FTD), characterized by progressive behavioral impairment and a decline in executive function with frontal lobe-predominant atrophy."
      },
      "child_count": 6,
      "reference_id": "MONDO:0017160"
    },
    {
      "id": 22128,
      "label": "frontotemporal dementia and/or amyotrophic lateral sclerosis",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        21292
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "GARD:0025663",
          "OMIMPS:105500"
        ],
        "categories": [
          {
            "ref": "MONDO:0005071",
            "name": "nervous system disorder"
          }
        ]
      },
      "child_count": 8,
      "reference_id": "MONDO:0030923"
    }
  ],
  "children": [],
  "roots": [
    {
      "id": 6868,
      "label": "familial amyotrophic lateral sclerosis"
    },
    {
      "id": 17505,
      "label": "behavioral variant of frontotemporal dementia"
    },
    {
      "id": 22128,
      "label": "frontotemporal dementia and/or amyotrophic lateral sclerosis"
    }
  ]
}