{
  "id": 12127,
  "label": "Brugada syndrome 1",
  "model": {
    "label": "Mondo Disease Ontology (MONDO)",
    "source": 0
  },
  "type_id": 0,
  "reference_id": "MONDO:0011001",
  "properties": {
    "xrefs": [
      "DOID:0110218",
      "GARD:0024766",
      "MEDGEN:1646402",
      "OMIM:601144",
      "UMLS:C4551804"
    ],
    "synonyms": [
      "BRGDA1",
      "Brugada syndrome 1",
      "Brugada syndrome caused by mutation in SCN5A",
      "Brugada syndrome type 1",
      "SCN5A Brugada syndrome",
      "Cardiac conduction defect, nonspecific",
      "right bundle branch block, St segment elevation, and sudden death syndrome",
      "sudden unexplained nocturnal death syndrome"
    ],
    "categories": [
      {
        "ref": "MONDO:0002254",
        "name": "syndromic disease"
      },
      {
        "ref": "MONDO:0004995",
        "name": "cardiovascular disorder"
      }
    ],
    "definition": "Any Brugada syndrome in which the cause of the disease is a mutation in the SCN5A gene."
  },
  "isLeaf": true,
  "isRoot": false,
  "child_count": 0,
  "parents": [
    {
      "id": 16147,
      "label": "Brugada syndrome",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        3258,
        4370,
        26601
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:0050451",
          "GARD:0001030",
          "ICD9:746.89",
          "MEDGEN:222975",
          "MESH:D053840",
          "MedDRA:10059027",
          "NCIT:C142891",
          "NORD:878",
          "OMIMPS:601144",
          "Orphanet:130",
          "SCTID:418818005",
          "UMLS:C1142166",
          "icd11.foundation:1250136584"
        ],
        "synonyms": [
          "Brugada syndrome",
          "Brugada type idiopathic ventricular fibrillation",
          "idiopathic ventricular fibrillation, Brugada type",
          "right bundle branch block, ST segment elevation, and sudden death syndrome",
          "sudden unexplained nocturnal death syndrome",
          "sudden unexpected nocturnal death syndrome"
        ],
        "categories": [
          {
            "ref": "MONDO:0002254",
            "name": "syndromic disease"
          },
          {
            "ref": "MONDO:0004995",
            "name": "cardiovascular disorder"
          }
        ],
        "definition": "A genetically heterogeneous condition characterized by complete or incomplete right bundle branch block accompanied by ST elevation in leads V1-V3. There is a high incidence of ventricular arrhythmia that may result in sudden death."
      },
      "child_count": 27,
      "reference_id": "MONDO:0015263"
    },
    {
      "id": 26602,
      "label": "SCN5A-related cardiac rhythm disorder",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        26601
      ],
      "type_id": 0,
      "properties": {
        "synonyms": [
          "SCN5A-related cardiac rhythm disorder"
        ],
        "categories": [
          {
            "ref": "MONDO:0004995",
            "name": "cardiovascular disorder"
          }
        ],
        "definition": "A heterogeneous collection of cardiac rhythm disorders caused by genetic variations in the SCN5A gene with autosomal dominant inheritance. Affected individuals are commonly reported to have unremarkable cardiac morphology and at least one cardiac rhythm phenotype that includes, but is not limited to, atrial fibrillation, sick sinus syndrome, progressive cardiac conduction disease, ventricular fibrillation, long QT syndrome, and Brugada syndrome."
      },
      "child_count": 6,
      "reference_id": "MONDO:1010181"
    }
  ],
  "children": [],
  "roots": [
    {
      "id": 16147,
      "label": "Brugada syndrome"
    },
    {
      "id": 26602,
      "label": "SCN5A-related cardiac rhythm disorder"
    }
  ]
}