{
  "id": 12186,
  "label": "early-onset non-syndromic cataract",
  "model": {
    "label": "Mondo Disease Ontology (MONDO)",
    "source": 0
  },
  "type_id": 0,
  "reference_id": "MONDO:0011060",
  "properties": {
    "xrefs": [
      "GARD:0016801",
      "MEDGEN:371326",
      "OMIM:601371",
      "Orphanet:91492",
      "UMLS:C1832423",
      "icd11.foundation:1080602978"
    ],
    "synonyms": [
      "cataract, age-related nuclear",
      "nuclear sclerosis of the lens"
    ],
    "categories": [
      {
        "ref": "MONDO:0002022",
        "name": "disorder of orbital region"
      },
      {
        "ref": "MONDO:0024458",
        "name": "disorder of visual system"
      }
    ],
    "definition": "Early-onset non-syndromic cataract is a rare, genetic, non-syndromic developmental defect of the eye, with high clinical and genetic heterogeneity, most frequently characterized by bilateral, symmetrical, non-progressive cataracts which present at birth or in early-childhood. Additional ocular manifestations (e.g. anterior segment dysgenesis, colobomas, nystagmus, microcornea, microphthalmia, myopia) may be associated, however other organs/systems are usually not affected."
  },
  "isLeaf": false,
  "isRoot": false,
  "child_count": 29,
  "parents": [
    {
      "id": 6853,
      "label": "cataract",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        3420,
        5714
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:83",
          "HP:0000518",
          "ICD9:366",
          "ICD9:366.44",
          "ICD9:366.8",
          "ICD9:366.9",
          "MEDGEN:39462",
          "MESH:D002386",
          "NCIT:C26713",
          "OMIMPS:116200",
          "SCTID:193570009",
          "UMLS:C0086543",
          "icd11.foundation:109841337"
        ],
        "synonyms": [
          "cataract",
          "cataract (disease)",
          "opacity of the lens"
        ],
        "categories": [
          {
            "ref": "MONDO:0002022",
            "name": "disorder of orbital region"
          },
          {
            "ref": "MONDO:0024458",
            "name": "disorder of visual system"
          }
        ],
        "definition": "Partial or complete opacity of the crystalline lens of one or both eyes that decreases visual acuity and eventually results in blindness. Some cataracts appear in infancy or in childhood, but most develop in older individuals. (Sternberg Diagnostic Surgical Pathology, 3rd ed.)"
      },
      "child_count": 58,
      "reference_id": "MONDO:0005129"
    }
  ],
  "children": [
    {
      "id": 8680,
      "label": "cataract 32 multiple types",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        12186
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:0110227",
          "GARD:0010236",
          "MEDGEN:854634",
          "OMIM:115650",
          "UMLS:C3887926"
        ],
        "synonyms": [
          "CTRCT32",
          "cataract 32, multiple types",
          "cataract, anterior polar",
          "cataract, anterior polar, 1",
          "cataract, posterior polar, 5"
        ],
        "categories": [
          {
            "ref": "MONDO:0002022",
            "name": "disorder of orbital region"
          },
          {
            "ref": "MONDO:0024458",
            "name": "disorder of visual system"
          }
        ],
        "definition": "A cataract that has material basis in mutation in the region 14q22-q23."
      },
      "child_count": 0,
      "reference_id": "MONDO:0007278"
    },
    {
      "id": 8682,
      "label": "cataract 8 multiple types",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        12186
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:0110228",
          "GARD:0001146",
          "MEDGEN:396230",
          "MESH:C538285",
          "OMIM:115665",
          "Orphanet:98983",
          "UMLS:C1861833"
        ],
        "synonyms": [
          "CTRCT8",
          "cataract, congenital, Volkmann type",
          "cataract 8, multiple types",
          "cataract congenital Volkmann type"
        ],
        "categories": [
          {
            "ref": "MONDO:0002022",
            "name": "disorder of orbital region"
          },
          {
            "ref": "MONDO:0024458",
            "name": "disorder of visual system"
          }
        ],
        "definition": "A cataract that has material basis in variation in the region 1pter-p36.13."
      },
      "child_count": 0,
      "reference_id": "MONDO:0007280"
    },
    {
      "id": 8685,
      "label": "cataract 42",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        12186
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:0110237",
          "GARD:0024543",
          "MEDGEN:859891",
          "OMIM:115900",
          "UMLS:C4011454"
        ],
        "synonyms": [
          "A cataract that has_material_basis_in heterozygous mutation in the CRYBA2 gene on chromosome 2q35.",
          "CRYBA2 early-onset non-syndromic cataract",
          "CTRCT42",
          "cataract 42",
          "cataract type 42",
          "early-onset non-syndromic cataract caused by mutation in CRYBA2"
        ],
        "categories": [
          {
            "ref": "MONDO:0002022",
            "name": "disorder of orbital region"
          },
          {
            "ref": "MONDO:0024458",
            "name": "disorder of visual system"
          }
        ],
        "definition": "Any early-onset non-syndromic cataract in which the cause of the disease is a mutation in the CRYBA2 gene."
      },
      "child_count": 0,
      "reference_id": "MONDO:0007283"
    },
    {
      "id": 8686,
      "label": "cataract 20 multiple types",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        12186
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:0110240",
          "GARD:0024544",
          "MEDGEN:101117",
          "OMIM:116100",
          "UMLS:C0524524"
        ],
        "synonyms": [
          "CRYGS cataract (disease)",
          "CTRCT20",
          "cataract (disease) caused by mutation in CRYGS",
          "cataract 20, multiple types"
        ],
        "categories": [
          {
            "ref": "MONDO:0002022",
            "name": "disorder of orbital region"
          },
          {
            "ref": "MONDO:0024458",
            "name": "disorder of visual system"
          }
        ],
        "definition": "Any cataract (disease) in which the cause of the disease is a mutation in the CRYGS gene."
      },
      "child_count": 0,
      "reference_id": "MONDO:0007284"
    },
    {
      "id": 8690,
      "label": "cataract 6 multiple types",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        12186
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:0110229",
          "GARD:0010234",
          "MEDGEN:396229",
          "OMIM:116600",
          "UMLS:C1861825"
        ],
        "synonyms": [
          "CTRCT6",
          "EPHA2 cataract (disease)",
          "cataract (disease) caused by mutation in EPHA2",
          "CTPA",
          "CTPP",
          "Posterior polar cataract, 1",
          "cataract 6, multiple types",
          "cataract, age-related cortical, 2",
          "cataract, posterior polar, 1"
        ],
        "categories": [
          {
            "ref": "MONDO:0002022",
            "name": "disorder of orbital region"
          },
          {
            "ref": "MONDO:0024458",
            "name": "disorder of visual system"
          }
        ],
        "definition": "Any cataract (disease) in which the cause of the disease is a mutation in the EPHA2 gene."
      },
      "child_count": 0,
      "reference_id": "MONDO:0007288"
    },
    {
      "id": 8691,
      "label": "cataract 13 with adult I phenotype",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        12186
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:0110242",
          "GARD:0024546",
          "MEDGEN:811703",
          "OMIM:116700",
          "UMLS:C3805373"
        ],
        "synonyms": [
          "CTRCT13",
          "cataract 13 with adult I phenotype",
          "cataract 13 with ADULT I phenotype"
        ],
        "categories": [
          {
            "ref": "MONDO:0002022",
            "name": "disorder of orbital region"
          },
          {
            "ref": "MONDO:0024458",
            "name": "disorder of visual system"
          }
        ],
        "definition": "A cataract that has material basis in homozygous or compound heterozygous mutation in the GCNT2 gene on chromosome 6p24."
      },
      "child_count": 0,
      "reference_id": "MONDO:0007289"
    },
    {
      "id": 8692,
      "label": "cataract 5 multiple types",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        12186
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:0110255",
          "GARD:0024547",
          "MEDGEN:78608",
          "MESH:C535342",
          "OMIM:116800",
          "UMLS:C0266537"
        ],
        "synonyms": [
          "CTRCT5",
          "HSF4 cataract (disease)",
          "cataract (disease) caused by mutation in HSF4",
          "cataract 5, multiple types",
          "cataract, Marner type",
          "cataract, lamellar"
        ],
        "categories": [
          {
            "ref": "MONDO:0002022",
            "name": "disorder of orbital region"
          },
          {
            "ref": "MONDO:0024458",
            "name": "disorder of visual system"
          }
        ],
        "definition": "Any cataract (disease) in which the cause of the disease is a mutation in the HSF4 gene."
      },
      "child_count": 0,
      "reference_id": "MONDO:0007290"
    },
    {
      "id": 10188,
      "label": "cataract 46 juvenile-onset",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        12186
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:0110243",
          "GARD:0001150",
          "MEDGEN:113102",
          "MESH:C538286",
          "OMIM:212500",
          "Orphanet:98987",
          "UMLS:C0220721"
        ],
        "synonyms": [
          "CTRCT46",
          "LEMD2 early-onset non-syndromic cataract",
          "early-onset non-syndromic cataract caused by mutation in LEMD2",
          "cataract 46, juvenile-onset",
          "cataract Hutterite type",
          "cataract, congenital or juvenile",
          "cataract, juvenile, Hutterite type"
        ],
        "categories": [
          {
            "ref": "MONDO:0002022",
            "name": "disorder of orbital region"
          },
          {
            "ref": "MONDO:0024458",
            "name": "disorder of visual system"
          }
        ],
        "definition": "Any early-onset non-syndromic cataract in which the cause of the disease is a mutation in the LEMD2 gene."
      },
      "child_count": 0,
      "reference_id": "MONDO:0008925"
    },
    {
      "id": 11699,
      "label": "cataract 40",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        12186
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:0110272",
          "GARD:0008278",
          "MEDGEN:886621",
          "MESH:C535338",
          "OMIM:302200",
          "UMLS:C4049004"
        ],
        "synonyms": [
          "CTRCT40",
          "NHS early-onset non-syndromic cataract",
          "cataract 40",
          "cataract 40 with or without microcornea",
          "cataract type 40",
          "early-onset non-syndromic cataract caused by mutation in NHS",
          "cataract 40, X-linked",
          "cataract congenital X-linked",
          "cataract, congenital total, with posterior sutural opacities in heterozygotes",
          "cataract, congenital, X-linked",
          "cataract, congenital, with microcornea or slight microphthalmia"
        ],
        "categories": [
          {
            "ref": "MONDO:0002022",
            "name": "disorder of orbital region"
          },
          {
            "ref": "MONDO:0024458",
            "name": "disorder of visual system"
          }
        ],
        "definition": "Any early-onset non-syndromic cataract in which the cause of the disease is a mutation in the NHS gene."
      },
      "child_count": 0,
      "reference_id": "MONDO:0010544"
    },
    {
      "id": 12078,
      "label": "cataract 10 multiple types",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        12186
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:0110258",
          "GARD:0024764",
          "MEDGEN:318817",
          "MESH:C563435",
          "OMIM:600881",
          "UMLS:C1833229"
        ],
        "synonyms": [
          "CRYBA1 early-onset non-syndromic cataract",
          "CTRCT10",
          "early-onset non-syndromic cataract caused by mutation in CRYBA1",
          "cataract 10, multiple types",
          "cataract, congenital zonular, with sutural opacities"
        ],
        "categories": [
          {
            "ref": "MONDO:0002022",
            "name": "disorder of orbital region"
          },
          {
            "ref": "MONDO:0024458",
            "name": "disorder of visual system"
          }
        ],
        "definition": "Any early-onset non-syndromic cataract in which the cause of the disease is a mutation in the CRYBA1 gene."
      },
      "child_count": 0,
      "reference_id": "MONDO:0010948"
    },
    {
      "id": 12284,
      "label": "cataract 14 multiple types",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        12186
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:0110253",
          "GARD:0024777",
          "MEDGEN:356152",
          "MESH:C566608",
          "OMIM:601885",
          "UMLS:C1866078"
        ],
        "synonyms": [
          "CTRCT14",
          "GJA3 early-onset non-syndromic cataract",
          "early-onset non-syndromic cataract caused by mutation in GJA3",
          "Cae3",
          "cataract 14, multiple types",
          "cataract, zonular pulverulent 3"
        ],
        "categories": [
          {
            "ref": "MONDO:0002022",
            "name": "disorder of orbital region"
          },
          {
            "ref": "MONDO:0024458",
            "name": "disorder of visual system"
          }
        ],
        "definition": "Any early-onset non-syndromic cataract in which the cause of the disease is a mutation in the GJA3 gene."
      },
      "child_count": 0,
      "reference_id": "MONDO:0011162"
    },
    {
      "id": 12535,
      "label": "pulverulent cataract",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        12186
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "GARD:0016884",
          "MEDGEN:318793",
          "MESH:C565133",
          "Orphanet:98984",
          "Orphanet:98986",
          "UMLS:C1833118",
          "icd11.foundation:1046743385"
        ],
        "synonyms": [
          "Coppock-like cataract",
          "dusty cataract",
          "pulverulent cataract"
        ],
        "categories": [
          {
            "ref": "MONDO:0002022",
            "name": "disorder of orbital region"
          },
          {
            "ref": "MONDO:0024458",
            "name": "disorder of visual system"
          }
        ],
        "definition": "A cataract that has material basis in heterozygous mutation in the CRYGC gene on chromosome 2q33."
      },
      "child_count": 0,
      "reference_id": "MONDO:0011430"
    },
    {
      "id": 12644,
      "label": "cataract 31 multiple types",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        12186
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:0110265",
          "GARD:0010227",
          "MEDGEN:343089",
          "MESH:C535343",
          "OMIM:605387",
          "UMLS:C1854311"
        ],
        "synonyms": [
          "CHMP4B early-onset non-syndromic cataract",
          "CTRCT31",
          "early-onset non-syndromic cataract caused by mutation in CHMP4B",
          "cataract 31, multiple types",
          "cataract, posterior polar, 3"
        ],
        "categories": [
          {
            "ref": "MONDO:0002022",
            "name": "disorder of orbital region"
          },
          {
            "ref": "MONDO:0024458",
            "name": "disorder of visual system"
          }
        ],
        "definition": "Any early-onset non-syndromic cataract in which the cause of the disease is a mutation in the CHMP4B gene."
      },
      "child_count": 0,
      "reference_id": "MONDO:0011547"
    },
    {
      "id": 12687,
      "label": "cataract 26 multiple types",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        12186
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:0110246",
          "GARD:0024812",
          "MEDGEN:381316",
          "MESH:C565298",
          "OMIM:605749",
          "UMLS:C1854003"
        ],
        "synonyms": [
          "CTRCT26",
          "cataract 26, multiple types",
          "cataract, autosomal recessive, early-onset, pulverulent"
        ],
        "categories": [
          {
            "ref": "MONDO:0002022",
            "name": "disorder of orbital region"
          },
          {
            "ref": "MONDO:0024458",
            "name": "disorder of visual system"
          }
        ],
        "definition": "A cataract that has material basis in variation in the region 9q13-q22."
      },
      "child_count": 0,
      "reference_id": "MONDO:0011591"
    },
    {
      "id": 13391,
      "label": "cataract 22 multiple types",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        12186
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:0110268",
          "GARD:0024861",
          "MEDGEN:341862",
          "MESH:C565725",
          "OMIM:609741",
          "UMLS:C1857853"
        ],
        "synonyms": [
          "CRYBB3 early-onset non-syndromic cataract",
          "CTRCT22",
          "cataract 22",
          "early-onset non-syndromic cataract caused by mutation in CRYBB3",
          "cataract 22, multiple types",
          "cataract, congenital nuclear, autosomal recessive 2"
        ],
        "categories": [
          {
            "ref": "MONDO:0002022",
            "name": "disorder of orbital region"
          },
          {
            "ref": "MONDO:0024458",
            "name": "disorder of visual system"
          }
        ],
        "definition": "Any early-onset non-syndromic cataract in which the cause of the disease is a mutation in the CRYBB3 gene."
      },
      "child_count": 0,
      "reference_id": "MONDO:0012336"
    },
    {
      "id": 13487,
      "label": "cataract 21 multiple types",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        12186
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:0110256",
          "GARD:0024866",
          "MEDGEN:347538",
          "MESH:C565703",
          "OMIM:610202",
          "UMLS:C1857768"
        ],
        "synonyms": [
          "CTRCT21",
          "MAF early-onset non-syndromic cataract",
          "early-onset non-syndromic cataract caused by mutation in MAF",
          "cataract 21, multiple types",
          "cataract 21, multiple types, with or without microcornea",
          "cataract, congenital, cerulean type, 4",
          "cataract, pulverulent, juvenile-onset"
        ],
        "categories": [
          {
            "ref": "MONDO:0002022",
            "name": "disorder of orbital region"
          },
          {
            "ref": "MONDO:0024458",
            "name": "disorder of visual system"
          }
        ],
        "definition": "Any early-onset non-syndromic cataract in which the cause of the disease is a mutation in the MAF gene."
      },
      "child_count": 0,
      "reference_id": "MONDO:0012437"
    },
    {
      "id": 13538,
      "label": "cataract 23",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        12186
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:0110271",
          "GARD:0024869",
          "MEDGEN:814342",
          "OMIM:610425",
          "UMLS:C3808012"
        ],
        "synonyms": [
          "CRYBA4 early-onset non-syndromic cataract",
          "CTRCT23",
          "cataract 23",
          "cataract type 23",
          "early-onset non-syndromic cataract caused by mutation in CRYBA4",
          "cataract 23, lamellar",
          "cataract 23, multiple types",
          "cataract 23, multiple types, with or without microcornea"
        ],
        "categories": [
          {
            "ref": "MONDO:0002022",
            "name": "disorder of orbital region"
          },
          {
            "ref": "MONDO:0024458",
            "name": "disorder of visual system"
          }
        ],
        "definition": "Any early-onset non-syndromic cataract in which the cause of the disease is a mutation in the CRYBA4 gene."
      },
      "child_count": 0,
      "reference_id": "MONDO:0012489"
    },
    {
      "id": 13575,
      "label": "cataract 11 multiple types",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        12186
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:0110249",
          "GARD:0010228",
          "MEDGEN:351162",
          "MESH:C535344",
          "OMIM:610623",
          "UMLS:C1864567"
        ],
        "synonyms": [
          "CTRCT11",
          "PITX3 early-onset non-syndromic cataract",
          "cataract 11, syndromic, autosomal recessive",
          "early-onset non-syndromic cataract caused by mutation in PITX3",
          "Cpp4",
          "Posterior polar cataract, 4",
          "cataract 11 with microphthalmia and neurodevelopmental abnormalities",
          "cataract 11, multiple types",
          "cataract, posterior polar, 4"
        ],
        "categories": [
          {
            "ref": "MONDO:0002022",
            "name": "disorder of orbital region"
          },
          {
            "ref": "MONDO:0024458",
            "name": "disorder of visual system"
          }
        ],
        "definition": "Any early-onset non-syndromic cataract in which the cause of the disease is a mutation in the PITX3 gene."
      },
      "child_count": 0,
      "reference_id": "MONDO:0012527"
    },
    {
      "id": 13705,
      "label": "cataract 33",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        12186
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:0110264",
          "GARD:0018236",
          "MEDGEN:814437",
          "MESH:C566955",
          "OMIM:611391",
          "Orphanet:217046",
          "Orphanet:217052",
          "UMLS:C3808107"
        ],
        "synonyms": [
          "BFSP1 early-onset non-syndromic cataract",
          "CTRCT33",
          "cataract 33",
          "cataract type 33",
          "early-onset non-syndromic cataract caused by mutation in BFSP1",
          "cataract 33, cortical",
          "cataract 33, multiple types"
        ],
        "categories": [
          {
            "ref": "MONDO:0002022",
            "name": "disorder of orbital region"
          },
          {
            "ref": "MONDO:0024458",
            "name": "disorder of visual system"
          }
        ],
        "definition": "Any early-onset non-syndromic cataract in which the cause of the disease is a mutation in the BFSP1 gene."
      },
      "child_count": 0,
      "reference_id": "MONDO:0012665"
    },
    {
      "id": 13728,
      "label": "cataract 17 multiple types",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        12186
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:0110270",
          "GARD:0024881",
          "MEDGEN:854781",
          "MESH:C566923",
          "OMIM:611544",
          "UMLS:C3888124"
        ],
        "synonyms": [
          "CRYBB1 early-onset non-syndromic cataract",
          "CTRCT17",
          "early-onset non-syndromic cataract caused by mutation in CRYBB1",
          "cataract 17, multiple types",
          "cataract 17, multiple types, with or without microcornea",
          "cataract, congenital nuclear, autosomal recessive 3"
        ],
        "categories": [
          {
            "ref": "MONDO:0002022",
            "name": "disorder of orbital region"
          },
          {
            "ref": "MONDO:0024458",
            "name": "disorder of visual system"
          }
        ],
        "definition": "Any early-onset non-syndromic cataract in which the cause of the disease is a mutation in the CRYBB1 gene."
      },
      "child_count": 0,
      "reference_id": "MONDO:0012688"
    },
    {
      "id": 14872,
      "label": "cataract 38",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        12186
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:0110245",
          "GARD:0024957",
          "MEDGEN:766408",
          "OMIM:614691",
          "UMLS:C3553494"
        ],
        "synonyms": [
          "AGK early-onset non-syndromic cataract",
          "CATC5",
          "CTRCT38",
          "cataract 38",
          "cataract 38, autosomal recessive",
          "cataract type 38",
          "early-onset non-syndromic cataract caused by mutation in AGK",
          "cataract, autosomal recessive congenital 5"
        ],
        "categories": [
          {
            "ref": "MONDO:0002022",
            "name": "disorder of orbital region"
          },
          {
            "ref": "MONDO:0024458",
            "name": "disorder of visual system"
          }
        ],
        "definition": "Any early-onset non-syndromic cataract in which the cause of the disease is a mutation in the AGK gene."
      },
      "child_count": 0,
      "reference_id": "MONDO:0013859"
    },
    {
      "id": 15084,
      "label": "cataract 39 multiple types",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        12186
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:0110236",
          "GARD:0024969",
          "MEDGEN:815130",
          "OMIM:615188",
          "UMLS:C3808800"
        ],
        "synonyms": [
          "CRYGB early-onset non-syndromic cataract",
          "CTRCT39",
          "cataract 39, multiple types, autosomal dominant",
          "early-onset non-syndromic cataract caused by mutation in CRYGB",
          "cataract 39, multiple types"
        ],
        "categories": [
          {
            "ref": "MONDO:0002022",
            "name": "disorder of orbital region"
          },
          {
            "ref": "MONDO:0024458",
            "name": "disorder of visual system"
          }
        ],
        "definition": "Any early-onset non-syndromic cataract in which the cause of the disease is a mutation in the CRYGB gene."
      },
      "child_count": 0,
      "reference_id": "MONDO:0014075"
    },
    {
      "id": 15118,
      "label": "cataract 15 multiple types",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        12186
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:0110251",
          "GARD:0024971",
          "MEDGEN:815331",
          "OMIM:615274",
          "UMLS:C3809001"
        ],
        "synonyms": [
          "CTRCT15",
          "MIP early-onset non-syndromic cataract",
          "early-onset non-syndromic cataract caused by mutation in MIP",
          "cataract 15, multiple types"
        ],
        "categories": [
          {
            "ref": "MONDO:0002022",
            "name": "disorder of orbital region"
          },
          {
            "ref": "MONDO:0024458",
            "name": "disorder of visual system"
          }
        ],
        "definition": "Any early-onset non-syndromic cataract in which the cause of the disease is a mutation in the MIP gene."
      },
      "child_count": 0,
      "reference_id": "MONDO:0014110"
    },
    {
      "id": 15119,
      "label": "cataract 19 multiple types",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        12186
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:0110263",
          "GARD:0024972",
          "MEDGEN:815334",
          "OMIM:615277",
          "UMLS:C3809004"
        ],
        "synonyms": [
          "CTRCT19",
          "LIM2 early-onset non-syndromic cataract",
          "cataract type 19",
          "early-onset non-syndromic cataract caused by mutation in LIM2",
          "cataract 19",
          "cataract 19, multiple types"
        ],
        "categories": [
          {
            "ref": "MONDO:0002022",
            "name": "disorder of orbital region"
          },
          {
            "ref": "MONDO:0024458",
            "name": "disorder of visual system"
          }
        ],
        "definition": "Any early-onset non-syndromic cataract in which the cause of the disease is a mutation in the LIM2 gene."
      },
      "child_count": 0,
      "reference_id": "MONDO:0014111"
    },
    {
      "id": 15563,
      "label": "cataract 43",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        12186
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:0110259",
          "GARD:0025003",
          "MEDGEN:901691",
          "OMIM:616279",
          "UMLS:C4225389"
        ],
        "synonyms": [
          "CTRCT43",
          "UNC45B early-onset non-syndromic cataract",
          "cataract 43",
          "cataract type 43",
          "early-onset non-syndromic cataract caused by mutation in UNC45B"
        ],
        "categories": [
          {
            "ref": "MONDO:0002022",
            "name": "disorder of orbital region"
          },
          {
            "ref": "MONDO:0024458",
            "name": "disorder of visual system"
          }
        ],
        "definition": "Any early-onset non-syndromic cataract in which the cause of the disease is a mutation in the UNC45B gene."
      },
      "child_count": 0,
      "reference_id": "MONDO:0014565"
    },
    {
      "id": 15668,
      "label": "cataract 44",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        12186
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:0110267",
          "GARD:0016127",
          "MEDGEN:907487",
          "OMIM:616509",
          "UMLS:C4225300"
        ],
        "synonyms": [
          "total early-onset cataract",
          "CTRCT44",
          "LSS early-onset non-syndromic cataract",
          "cataract 44",
          "cataract type 44",
          "early-onset non-syndromic cataract caused by mutation in LSS"
        ],
        "categories": [
          {
            "ref": "MONDO:0002022",
            "name": "disorder of orbital region"
          },
          {
            "ref": "MONDO:0024458",
            "name": "disorder of visual system"
          }
        ],
        "definition": "Any early-onset non-syndromic cataract in which the cause of the disease is a mutation in the LSS gene."
      },
      "child_count": 0,
      "reference_id": "MONDO:0014673"
    },
    {
      "id": 15787,
      "label": "cataract 45",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        12186
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:0110262",
          "GARD:0025016",
          "MEDGEN:895198",
          "OMIM:616851",
          "UMLS:C4225182"
        ],
        "synonyms": [
          "CTRCT45",
          "SIPA1L3 early-onset non-syndromic cataract",
          "cataract 45",
          "cataract type 45",
          "early-onset non-syndromic cataract caused by mutation in SIPA1L3"
        ],
        "categories": [
          {
            "ref": "MONDO:0002022",
            "name": "disorder of orbital region"
          },
          {
            "ref": "MONDO:0024458",
            "name": "disorder of visual system"
          }
        ],
        "definition": "Any early-onset non-syndromic cataract in which the cause of the disease is a mutation in the SIPA1L3 gene."
      },
      "child_count": 0,
      "reference_id": "MONDO:0014799"
    },
    {
      "id": 19837,
      "label": "early-onset partial cataract",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        12186
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "GARD:0016888",
          "MEDGEN:1842758",
          "Orphanet:98992",
          "UMLS:C5681643"
        ],
        "categories": [
          {
            "ref": "MONDO:0002022",
            "name": "disorder of orbital region"
          },
          {
            "ref": "MONDO:0024458",
            "name": "disorder of visual system"
          }
        ]
      },
      "child_count": 5,
      "reference_id": "MONDO:0020377"
    },
    {
      "id": 20663,
      "label": "total early-onset cataract",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        12186
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "GARD:0001159",
          "MEDGEN:75616",
          "Orphanet:98994",
          "UMLS:C0266539"
        ],
        "synonyms": [
          "CCT",
          "cataract, total congenital",
          "cataract, total congenital with posterior sutural opacities in heterozygotes"
        ],
        "categories": [
          {
            "ref": "MONDO:0002022",
            "name": "disorder of orbital region"
          },
          {
            "ref": "MONDO:0024458",
            "name": "disorder of visual system"
          }
        ]
      },
      "child_count": 0,
      "reference_id": "MONDO:0021548"
    }
  ],
  "roots": [
    {
      "id": 6853,
      "label": "cataract"
    }
  ]
}