{
  "id": 12344,
  "label": "monomelic amyotrophy",
  "model": {
    "label": "Mondo Disease Ontology (MONDO)",
    "source": 0
  },
  "type_id": 0,
  "reference_id": "MONDO:0011224",
  "properties": {
    "xrefs": [
      "EFO:1001989",
      "GARD:0009697",
      "MEDGEN:356265",
      "MESH:C538253",
      "MedDRA:10069681",
      "OMIM:602440",
      "Orphanet:65684",
      "UMLS:C1865384",
      "icd11.foundation:2090347823"
    ],
    "synonyms": [
      "Hirayama disease",
      "JMADUE",
      "benign focal amyotrophy",
      "juvenile muscular atrophy of distal upper extremity",
      "juvenile muscular atrophy of the distal upper limb",
      "amyotrophy, monomelic",
      "spinal muscular atrophy juvenile nonprogressive",
      "spinal muscular atrophy, juvenile, nonprogressive"
    ],
    "categories": [
      {
        "ref": "MONDO:0005071",
        "name": "nervous system disorder"
      }
    ],
    "definition": "Monomelic amyotrophy (MA) is a rare benign lower motor neuron disorder characterized by muscular weakness and wasting in the distal upper extremities during adolescence followed by a spontaneous halt in progression and a stabilization of symptoms."
  },
  "isLeaf": false,
  "isRoot": false,
  "child_count": 1,
  "parents": [
    {
      "id": 19750,
      "label": "acquired motor neuron disease",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        19749
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "GARD:0019479",
          "MEDGEN:1842733",
          "Orphanet:98506",
          "UMLS:C5680367"
        ],
        "synonyms": [
          "acquired anterior horn cell disease",
          "acquired motor neuron disease"
        ],
        "categories": [
          {
            "ref": "MONDO:0005071",
            "name": "nervous system disorder"
          }
        ],
        "definition": "An instance of motor neuron disease that is acquired during the lifetime of the individual."
      },
      "child_count": 3,
      "reference_id": "MONDO:0020129"
    }
  ],
  "children": [
    {
      "id": 20001,
      "label": "O'Sullivan-McLeod syndrome",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        12344
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "GARD:0019718",
          "MEDGEN:797656",
          "MedDRA:10069682",
          "Orphanet:99965",
          "UMLS:C2721741"
        ],
        "categories": [
          {
            "ref": "MONDO:0005071",
            "name": "nervous system disorder"
          }
        ],
        "definition": "O'Sullivan McLeod syndrome is a benign lower motor neuron disorder and a rare variant of monomelic amyotrophy (MA), characterized by an initial unilateral weakness in the intrinsic hand muscles that eventually spreads to the opposite limb (with an asymmetrical distribution) and that has a very slow progression of muscular atrophy over a 20 year period."
      },
      "child_count": 0,
      "reference_id": "MONDO:0020559"
    }
  ],
  "roots": [
    {
      "id": 19750,
      "label": "acquired motor neuron disease"
    }
  ]
}