{
  "id": 12415,
  "label": "Huntington disease-like 1",
  "model": {
    "label": "Mondo Disease Ontology (MONDO)",
    "source": 0
  },
  "type_id": 0,
  "reference_id": "MONDO:0011299",
  "properties": {
    "xrefs": [
      "DOID:0090103",
      "GARD:0016985",
      "MEDGEN:355137",
      "MESH:C566398",
      "OMIM:603218",
      "Orphanet:157941",
      "UMLS:C1864112"
    ],
    "synonyms": [
      "HDL1",
      "HLN1",
      "Huntington disease-like 1",
      "Huntington disease-like type 1",
      "Huntington-like neurodegenerative disorder 1",
      "PRNP neurodegenerative disease with chorea",
      "early-onset prion disease with prominent psychiatric features",
      "neurodegenerative disease with chorea caused by mutation in PRNP",
      "Huntington's disease-like 1",
      "Huntington-like neurodegenerative disorder, autosomal dominant",
      "prion disease, early-onset, with prominent psychiatric features"
    ],
    "categories": [
      {
        "ref": "MONDO:0005071",
        "name": "nervous system disorder"
      }
    ],
    "definition": "Any neurodegenerative disease with chorea in which the cause of the disease is a mutation in the PRNP gene."
  },
  "isLeaf": true,
  "isRoot": false,
  "child_count": 0,
  "parents": [
    {
      "id": 7097,
      "label": "prion disease",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        7209,
        21534
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:649",
          "EFO:0004720",
          "GARD:0024183",
          "ICD9:046.19",
          "MEDGEN:56445",
          "MESH:D017096",
          "NANDO:1200186",
          "NCIT:C128346",
          "SCTID:230284004",
          "UMLS:C0162534"
        ],
        "synonyms": [
          "spongiform encephalopathy"
        ],
        "categories": [
          {
            "ref": "MONDO:0005071",
            "name": "nervous system disorder"
          }
        ],
        "definition": "A transmissible disease that is caused by a protein that is able to induce abnormal folding of normal cellular proteins, leading to characteristic spongiform brain changes, which are associated with neuronal loss without an inflammatory response. Such disorders have typically long incubation periods, but are then generally rapidly progressive and are uniformly fatal."
      },
      "child_count": 20,
      "reference_id": "MONDO:0005429"
    },
    {
      "id": 21292,
      "label": "inherited neurodegenerative disorder",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        7208,
        24270
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "GARD:0020280",
          "MEDGEN:1825988",
          "MESH:D020271",
          "NCIT:C97073",
          "Orphanet:183500",
          "UMLS:C5680568"
        ],
        "synonyms": [
          "genetic neurodegenerative disease",
          "hereditary neurodegenerative disease",
          "hereditary neurodegenerative disorder"
        ],
        "categories": [
          {
            "ref": "MONDO:0005071",
            "name": "nervous system disorder"
          }
        ],
        "definition": "An inherited disorder characterized by progressive degeneration and atrophy of the nervous system."
      },
      "child_count": 164,
      "reference_id": "MONDO:0024237"
    }
  ],
  "children": [],
  "roots": [
    {
      "id": 7097,
      "label": "prion disease"
    },
    {
      "id": 21292,
      "label": "inherited neurodegenerative disorder"
    }
  ]
}