{
  "id": 12476,
  "label": "ovarian germ cell tumor",
  "model": {
    "label": "Mondo Disease Ontology (MONDO)",
    "source": 0
  },
  "type_id": 0,
  "reference_id": "MONDO:0011366",
  "properties": {
    "xrefs": [
      "DOID:2156",
      "EFO:1000419",
      "GARD:0024792",
      "ICD9:239.5",
      "MEDGEN:65958",
      "NCIT:C3873",
      "OMIM:603737",
      "ONCOTREE:OGCT",
      "SCTID:237059008",
      "UMLS:C0238324"
    ],
    "synonyms": [
      "germ cell neoplasm of ovary",
      "germ cell neoplasm of the ovary",
      "germ cell tumor of ovary",
      "germ cell tumor of the ovary",
      "germ cell tumour of ovary",
      "germ cell tumour of the ovary",
      "ovarian germ cell neoplasm",
      "ovarian germ cell tumor",
      "ovary germ cell tumor",
      "ovary germ cell tumour",
      "ovarian germ cell cancer"
    ],
    "categories": [
      {
        "ref": "MONDO:0005039",
        "name": "reproductive system disorder"
      },
      {
        "ref": "MONDO:0005151",
        "name": "endocrine system disorder"
      }
    ],
    "definition": "A neoplasm that arises from the ovary and originates from germ cells. Representative examples include teratoma, embryonal carcinoma, yolk sac tumor, and dysgerminoma."
  },
  "isLeaf": false,
  "isRoot": false,
  "child_count": 4,
  "parents": [
    {
      "id": 6773,
      "label": "germ cell tumor",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        6798
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:2994",
          "EFO:0000514",
          "GARD:0013022",
          "MEDGEN:60030",
          "NCIT:C3708",
          "UMLS:C0205851"
        ],
        "synonyms": [
          "germ cell neoplasm",
          "germ cell tumor",
          "neoplasm of germ cell",
          "neoplasm of the germ cell",
          "tumor of germ cell",
          "tumor of the germ cell",
          "tumour of germ cell",
          "tumour of the germ cell",
          "germ cell cancer",
          "germ cells tumors",
          "germ cells tumours",
          "malignant tumour of the germ cell"
        ],
        "definition": "A benign or malignant, gonadal or extragonadal neoplasm that originates from germ cells. Representative examples include teratoma, seminoma, embryonal carcinoma, and yolk sac tumor."
      },
      "child_count": 13,
      "reference_id": "MONDO:0005040"
    },
    {
      "id": 20309,
      "label": "ovarian neoplasm",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        7207,
        20384
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "EFO:0003893",
          "ICD9:239.5",
          "MEDGEN:181539",
          "NCIT:C4984",
          "SCTID:123843001",
          "UMLS:C0919267"
        ],
        "synonyms": [
          "neoplasm of ovary",
          "neoplasm of the ovary",
          "ovarian neoplasm",
          "ovarian tumor",
          "ovarian tumors",
          "ovarian tumour",
          "ovarian tumours",
          "ovary neoplasm",
          "ovary neoplasm (disease)",
          "ovary tumor",
          "ovary tumour",
          "tumor of ovary",
          "tumor of the ovary",
          "tumour of ovary",
          "tumour of the ovary"
        ],
        "categories": [
          {
            "ref": "MONDO:0005039",
            "name": "reproductive system disorder"
          },
          {
            "ref": "MONDO:0005151",
            "name": "endocrine system disorder"
          }
        ],
        "definition": "A benign, borderline, or malignant neoplasm involving the ovary."
      },
      "child_count": 16,
      "reference_id": "MONDO:0021068"
    }
  ],
  "children": [
    {
      "id": 5222,
      "label": "ovarian cystic teratoma",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        4476,
        12476
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:5118",
          "GARD:0023433",
          "MEDGEN:235415",
          "NCIT:C7283",
          "UMLS:C1335155"
        ],
        "synonyms": [
          "ovary cystic teratoma"
        ],
        "categories": [
          {
            "ref": "MONDO:0005039",
            "name": "reproductive system disorder"
          },
          {
            "ref": "MONDO:0005151",
            "name": "endocrine system disorder"
          }
        ],
        "definition": "A teratoma that arises from the ovary and is characterized by the presence of cystic structures. Representative example is the dermoid cyst."
      },
      "child_count": 2,
      "reference_id": "MONDO:0003281"
    },
    {
      "id": 5640,
      "label": "pediatric ovarian germ cell tumor",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        5631,
        12476
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:6084",
          "GARD:0023655",
          "MEDGEN:162990",
          "NCIT:C8588",
          "UMLS:C0796664"
        ],
        "synonyms": [
          "ovarian germ cell tumor",
          "ovarian germ cell tumour",
          "childhood ovarian germ cell neoplasm",
          "childhood ovarian germ cell tumor",
          "childhood ovarian germ cell tumour",
          "ovarian germ cell tumor of childhood",
          "ovarian germ cell tumour of childhood",
          "pediatric ovarian germ cell neoplasm",
          "pediatric ovarian germ cell tumor"
        ],
        "categories": [
          {
            "ref": "MONDO:0005039",
            "name": "reproductive system disorder"
          },
          {
            "ref": "MONDO:0005151",
            "name": "endocrine system disorder"
          }
        ],
        "definition": "A germ cell tumor that arises from the ovary and occurs in children."
      },
      "child_count": 10,
      "reference_id": "MONDO:0003760"
    },
    {
      "id": 7245,
      "label": "ovarian teratoma",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        7786,
        12476
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:5567",
          "EFO:0006463",
          "GARD:0024209",
          "MEDGEN:76072",
          "NCIT:C8110",
          "SCTID:716077006",
          "UMLS:C0280131",
          "icd11.foundation:1752240825"
        ],
        "synonyms": [
          "germ cell teratoma of ovary",
          "germ cell teratoma of the ovary",
          "ovarian germ cell teratoma",
          "ovarian teratoma",
          "teratoma of ovary",
          "teratoma of the ovary"
        ],
        "categories": [
          {
            "ref": "MONDO:0005039",
            "name": "reproductive system disorder"
          },
          {
            "ref": "MONDO:0005151",
            "name": "endocrine system disorder"
          }
        ],
        "definition": "A non-seminomatous germ cell tumor arising from the ovary. It is characterized by the presence of various tissues which correspond to the different germinal layers (endoderm, mesoderm, and ectoderm). According to the level of differentiation of the tissues which comprise the tumor, ovarian teratomas are classified as mature or immature. Mature teratomas are composed of well differentiated, adult-type tissues. Immature teratomas are composed of immature, fetal type-tissues. Mature ovarian teratomas without a fetal-type component have an excellent outcome. The prognosis of immature ovarian teratomas is related to the grade and stage of the tumor."
      },
      "child_count": 6,
      "reference_id": "MONDO:0005602"
    },
    {
      "id": 18315,
      "label": "malignant germ cell tumor of ovary",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        7832,
        12476,
        18335,
        18448
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:2155",
          "GARD:0009330",
          "MEDGEN:87544",
          "NCIT:C4514",
          "Orphanet:35807",
          "SCTID:254869000",
          "UMLS:C0346180"
        ],
        "synonyms": [
          "MOGCT",
          "malignant germ cell neoplasm of ovary",
          "malignant germ cell neoplasm of the ovary",
          "malignant germ cell tumor of ovary",
          "malignant germ cell tumor of the ovary",
          "malignant germ cell tumour of the ovary",
          "malignant ovarian germ cell neoplasm",
          "malignant ovarian germ cell tumor",
          "malignant ovarian germ cell tumour",
          "ovarian germ cell cancer",
          "ovary malignant germ cell tumor",
          "ovary malignant germ cell tumour"
        ],
        "categories": [
          {
            "ref": "MONDO:0005039",
            "name": "reproductive system disorder"
          },
          {
            "ref": "MONDO:0005151",
            "name": "endocrine system disorder"
          }
        ],
        "definition": "Malignant germ cell tumor of ovary is a rare ovarian cancer arising from germ cells in the ovary, frequently unilateral at diagnosis which characteristically presents during adolescence with pelvic mass, fever, vaginal bleeding and acute abdomen."
      },
      "child_count": 16,
      "reference_id": "MONDO:0018171"
    }
  ],
  "roots": [
    {
      "id": 6773,
      "label": "germ cell tumor"
    },
    {
      "id": 20309,
      "label": "ovarian neoplasm"
    }
  ]
}