{
  "id": 12504,
  "label": "alpha thalassemia spectrum",
  "model": {
    "label": "Mondo Disease Ontology (MONDO)",
    "source": 0
  },
  "type_id": 0,
  "reference_id": "MONDO:0011399",
  "properties": {
    "xrefs": [
      "DOID:1099",
      "GARD:0000621",
      "ICD10CM:D56.0",
      "ICD9:282.43",
      "ICD9:282.49",
      "MEDGEN:1434",
      "MESH:D017085",
      "MedDRA:10043390",
      "NANDO:2201273",
      "NCIT:C34368",
      "OMIM:604131",
      "Orphanet:846",
      "SCTID:68913001",
      "UMLS:C0002312",
      "icd11.foundation:531667506"
    ],
    "synonyms": [
      "alpha thalassaemia",
      "alpha thalassemia spectrum",
      "alpha-thalassemia",
      "thalassemia, alpha-",
      "thalassemias, alpha-",
      "A-thalassemia",
      "alpha-thalassemia trait"
    ],
    "categories": [
      {
        "ref": "MONDO:0005570",
        "name": "hematologic disorder"
      }
    ],
    "definition": "An inherited hemoglobinopathy characterized by impaired synthesis of alpha-globin chains leading to a variable clinical picture depending on the number of affected alleles."
  },
  "isLeaf": false,
  "isRoot": false,
  "child_count": 2,
  "parents": [
    {
      "id": 3252,
      "label": "thalassemia",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        18953
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:10241",
          "EFO:1001996",
          "GARD:0007756",
          "ICD10CM:D56",
          "ICD9:282.4",
          "ICD9:282.40",
          "ICD9:282.49",
          "MEDGEN:21121",
          "MESH:D013789",
          "NANDO:2200626",
          "NCIT:C35069",
          "SCTID:40108008",
          "UMLS:C0039730"
        ],
        "synonyms": [
          "sickle-cell thalassemia with crisis",
          "sickle-cell thalassemia without crisis"
        ],
        "categories": [
          {
            "ref": "MONDO:0005570",
            "name": "hematologic disorder"
          }
        ],
        "definition": "An inherited blood disorder characterized by a decreased synthesis of one of the polypeptide chains that form hemoglobin. Anemia results from this abnormal hemoglobin formation."
      },
      "child_count": 2,
      "reference_id": "MONDO:0000984"
    }
  ],
  "children": [
    {
      "id": 24288,
      "label": "digenic alpha thalassemia spectrum",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        12504
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "GARD:0026282"
        ],
        "categories": [
          {
            "ref": "MONDO:0005570",
            "name": "hematologic disorder"
          }
        ],
        "definition": "An instance of alpha thalessemia spectrum that is caused by an inherited multiallelic modification in an individual."
      },
      "child_count": 3,
      "reference_id": "MONDO:0100563"
    },
    {
      "id": 24290,
      "label": "monogenic alpha thalassemia spectrum",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        12504
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "GARD:0026284"
        ],
        "categories": [
          {
            "ref": "MONDO:0005570",
            "name": "hematologic disorder"
          }
        ],
        "definition": "An instance of alpha thalessemia spectrum that is caused by an inherited monogenomic modification in an individual."
      },
      "child_count": 2,
      "reference_id": "MONDO:0100565"
    }
  ],
  "roots": [
    {
      "id": 3252,
      "label": "thalassemia"
    }
  ]
}