{
  "id": 12600,
  "label": "Becker nevus syndrome",
  "model": {
    "label": "Mondo Disease Ontology (MONDO)",
    "source": 0
  },
  "type_id": 0,
  "reference_id": "MONDO:0011500",
  "properties": {
    "xrefs": [
      "GARD:0005901",
      "MEDGEN:347608",
      "MESH:C565735",
      "OMIM:604919",
      "Orphanet:64755",
      "UMLS:C1858042"
    ],
    "synonyms": [
      "Becker nevus syndrome",
      "pigmentary hairy epidermal nevus",
      "hairy epidermal nevus syndrome"
    ],
    "categories": [
      {
        "ref": "MONDO:0002051",
        "name": "integumentary system disorder"
      }
    ],
    "definition": "Becker nevus syndrome is characterized by the presence of a Becker nevus in association with underdevelopment (hypoplasia) of the breast or other skin-related, muscular, or skeletal defects, all of which usually involve the same side of the bodyas the nevus (ipsilateral). Specific signs and symptoms in addition to the nevus may include ipsilateral breast hypoplasia; skeletal abnormalities such ashypoplasia of the shoulder girdle, scoliosis, fused ribs, and ipsilateral shortness of the arm; and several other features. Thecondition is thought to be sporadic (occurring in individuals with no history of the condition in the family). Treatment varies depending upon the specific symptoms present and the extent of the condition in the affected individual."
  },
  "isLeaf": false,
  "isRoot": false,
  "child_count": 1,
  "parents": [
    {
      "id": 6801,
      "label": "melanocytic nevus",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        20564,
        20680
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "EFO:0009675",
          "MEDGEN:14364",
          "MESH:D009506",
          "NCIT:C7570",
          "SCTID:400096001",
          "UMLS:C0027962",
          "Wikipedia:Nevus"
        ],
        "synonyms": [
          "melanocytic Nevus",
          "melanotic Nevus",
          "mole",
          "mole of skin",
          "nevus"
        ],
        "categories": [
          {
            "ref": "MONDO:0002051",
            "name": "integumentary system disorder"
          }
        ],
        "definition": "A neoplasm composed of melanocytes that usually appears as a dark spot on the skin."
      },
      "child_count": 56,
      "reference_id": "MONDO:0005073"
    },
    {
      "id": 19507,
      "label": "developmental defect during embryogenesis",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        20383
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "ICD9:759.7",
          "MEDGEN:1825997",
          "NCIT:C99267",
          "Orphanet:93890",
          "SCTID:400038003",
          "UMLS:C5680284"
        ],
        "synonyms": [
          "congenital malformation syndrome",
          "developmental defect during embryogenesis",
          "disorder of embryonic morphogenesis",
          "embryonic morphogenesis disease",
          "malformation syndrome",
          "rare developmental defect during embryogenesis"
        ],
        "definition": "A disease that has its basis in the disruption of embryonic morphogenesis."
      },
      "child_count": 52,
      "reference_id": "MONDO:0019755"
    },
    {
      "id": 23867,
      "label": "hereditary skin disorder",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        5714,
        6820
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "MESH:D012873",
          "SCTID:239001006"
        ],
        "synonyms": [
          "disease, genetic skin",
          "diseases, genetic skin",
          "genetic skin disease",
          "genetic skin diseases",
          "genodermatosis",
          "skin disease, genetic"
        ],
        "categories": [
          {
            "ref": "MONDO:0002051",
            "name": "integumentary system disorder"
          }
        ],
        "definition": "An instance of skin disease that is caused by a modification of the individual's genome."
      },
      "child_count": 228,
      "reference_id": "MONDO:0100118"
    }
  ],
  "children": [
    {
      "id": 14710,
      "label": "linear and whorled nevoid hypermelanosis",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        7993,
        12600,
        19140
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "GARD:0011004",
          "MEDGEN:473394",
          "NCIT:C3924",
          "OMIM:614323",
          "Orphanet:79150",
          "SCTID:403803002",
          "UMLS:C1304501"
        ],
        "synonyms": [
          "Becker Nevus",
          "Becker's Nevus",
          "linear papular ectodermal-mesodermal hamartoma",
          "melanosis Neviformis",
          "pigmented hairy Epidermal Nevus",
          "pigmented hairy Nevus of Becker",
          "progressive cribriform and zosteriform hyperpigmentation",
          "LWNH",
          "hyperpigmentation, progressive cribriform and zosteriform",
          "linear and whorled hypermelanosis",
          "nevoid hypermelanosis, linear and whorled",
          "reticulate hyperpigmentation of Iijima",
          "zebra-like hyperpigmentation",
          "zosteriform hyperpigmentation",
          "zosteriform lentiginous nevus"
        ],
        "categories": [
          {
            "ref": "MONDO:0002051",
            "name": "integumentary system disorder"
          }
        ],
        "definition": "Linear and whorled nevoid hypermelanosis (LWNH) is a rare skin condition characterized by swirling streaks of hyperpigmented (darkened) skin. The pigmentation follows the lines of Blashko and is mainly located on the trunk and limbs. It is present at birth or appears in the first few weeks of life. It typically progresses for one to two years and then stabilizes. Hyperpigmentation is usually the only symptom but there are isolated reports of other symptoms, involving mostly the central nervous system, musculoskeletal system, and heart. While most cases of LWNH are sporadic, apparent genetic transmission rarely has been described. A few people with LWNH have been diagnosed with chromosomal mosaicism."
      },
      "child_count": 0,
      "reference_id": "MONDO:0013688"
    }
  ],
  "roots": [
    {
      "id": 6801,
      "label": "melanocytic nevus"
    },
    {
      "id": 19507,
      "label": "developmental defect during embryogenesis"
    },
    {
      "id": 23867,
      "label": "hereditary skin disorder"
    }
  ]
}