{
  "id": 12873,
  "label": "familial meningioma",
  "model": {
    "label": "Mondo Disease Ontology (MONDO)",
    "source": 0
  },
  "type_id": 0,
  "reference_id": "MONDO:0011789",
  "properties": {
    "xrefs": [
      "DOID:4586",
      "GARD:0018385",
      "MEDGEN:764829",
      "MESH:C537443",
      "NCIT:C5301",
      "OMIM:607174",
      "UMLS:C3551915"
    ],
    "synonyms": [
      "meningioma",
      "familial meningioma",
      "hereditary meningioma",
      "hereditary meningioma (disease)",
      "meningioma, NF2-related, somatic",
      "meningioma, SIS-related",
      "meningioma, familial, susceptibility to",
      "susceptibility to familial meningioma"
    ],
    "categories": [
      {
        "ref": "MONDO:0005071",
        "name": "nervous system disorder"
      }
    ],
    "definition": "A meningioma that is transmitted from the parents to an offspring."
  },
  "isLeaf": true,
  "isRoot": false,
  "child_count": 0,
  "parents": [
    {
      "id": 17113,
      "label": "meningioma",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        17192
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:3565",
          "GARD:0007015",
          "HP:0002858",
          "ICDO:9530/0",
          "MEDGEN:7532",
          "MESH:D008579",
          "MedDRA:10027191",
          "NANDO:2200094",
          "NCIT:C3230",
          "NORD:1434",
          "ONCOTREE:MNG",
          "Orphanet:2495",
          "SCTID:302820008",
          "UMLS:C0025286",
          "icd11.foundation:672106711"
        ],
        "synonyms": [
          "meningioma",
          "meningioma (disease)",
          "intracranial meningioma",
          "meningeal neoplasm",
          "meningothelial cell tumor",
          "meningothelial cell tumour",
          "primary meningeal tumor",
          "primary meningeal tumour",
          "supratentorial meningioma"
        ],
        "categories": [
          {
            "ref": "MONDO:0005071",
            "name": "nervous system disorder"
          }
        ],
        "definition": "A generally slow growing tumor attached to the dura mater. It is composed of neoplastic meningothelial (arachnoidal) cells. It typically occurs in adults, often women and it has a wide range of histopathological appearances. Of the various subtypes, meningothelial, fibrous and transitional meningiomas are the most common. Most meningiomas are WHO grade I tumors, and some are WHO grade II or III tumors. Most subtypes share a common clinical behavior, although some subtypes are more likely to recur and follow a more aggressive clinical course. (Adapted from WHO)"
      },
      "child_count": 37,
      "reference_id": "MONDO:0016642"
    },
    {
      "id": 20011,
      "label": "inherited disease susceptibility",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        23063
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "ICD10CM:Z15",
          "MEDGEN:1876499",
          "MESH:D020022",
          "UMLS:C1455997"
        ],
        "synonyms": [
          "hereditary disease susceptibility",
          "hereditary predisposition to disease",
          "genetic predisposition",
          "genetic predispositions",
          "genetic susceptibilities",
          "genetic susceptibility",
          "predisposition, genetic",
          "predispositions, genetic",
          "susceptibilities, genetic",
          "susceptibility, genetic"
        ],
        "definition": "A latent susceptibility to disease at the genetic level, which may be activated under certain conditions."
      },
      "child_count": 284,
      "reference_id": "MONDO:0020573"
    },
    {
      "id": 24270,
      "label": "hereditary neurological disease",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        5714,
        6799
      ],
      "type_id": 0,
      "properties": {
        "synonyms": [
          "neurogenetic disease"
        ],
        "categories": [
          {
            "ref": "MONDO:0005071",
            "name": "nervous system disorder"
          }
        ],
        "definition": "A heterogeneous group of genetic conditions with Mendelian (autosomal dominant, recessive, or X-linked) or chromosomal etiology characterized by abnormalities in the brain, spinal cord, nerves, or muscles."
      },
      "child_count": 528,
      "reference_id": "MONDO:0100545"
    }
  ],
  "children": [],
  "roots": [
    {
      "id": 17113,
      "label": "meningioma"
    },
    {
      "id": 20011,
      "label": "inherited disease susceptibility"
    },
    {
      "id": 24270,
      "label": "hereditary neurological disease"
    }
  ]
}