{
  "id": 12879,
  "label": "infantile-onset ascending hereditary spastic paralysis",
  "model": {
    "label": "Mondo Disease Ontology (MONDO)",
    "source": 0
  },
  "type_id": 0,
  "reference_id": "MONDO:0011797",
  "properties": {
    "xrefs": [
      "GARD:0004914",
      "ICD9:343.8",
      "MEDGEN:419413",
      "MESH:C537217",
      "OMIM:607225",
      "Orphanet:293168",
      "SCTID:703543005",
      "UMLS:C2931441"
    ],
    "synonyms": [
      "IAHSP",
      "spastic paralysis, infantile onset ascending",
      "spastic paralysis, infantile-onset ascending"
    ],
    "categories": [
      {
        "ref": "MONDO:0005071",
        "name": "nervous system disorder"
      }
    ],
    "definition": "Infantile-onset ascending hereditary spastic paralysis (IAHSP) is a very rare motor neuron disease characterized by severe spasticity of the lower limbs in early life, progression of spasticity to the upper limbs in late childhood, and dysarthria."
  },
  "isLeaf": true,
  "isRoot": false,
  "child_count": 0,
  "parents": [
    {
      "id": 23968,
      "label": "ALS2-related motor neuron disease",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        21302
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "GARD:0026088"
        ],
        "synonyms": [
          "Alsin-related motor neuron disease"
        ],
        "categories": [
          {
            "ref": "MONDO:0005071",
            "name": "nervous system disorder"
          }
        ],
        "definition": "Any motor neuron disease in which the cause of the disease is a mutation in the ALS2 gene."
      },
      "child_count": 3,
      "reference_id": "MONDO:0100227"
    }
  ],
  "children": [],
  "roots": [
    {
      "id": 23968,
      "label": "ALS2-related motor neuron disease"
    }
  ]
}