{
  "id": 12899,
  "label": "isolated focal cortical dysplasia type II",
  "model": {
    "label": "Mondo Disease Ontology (MONDO)",
    "source": 0
  },
  "type_id": 0,
  "reference_id": "MONDO:0011818",
  "properties": {
    "xrefs": [
      "GARD:0010190",
      "MEDGEN:339510",
      "MESH:C537067",
      "OMIM:607341",
      "Orphanet:268994",
      "UMLS:C1846385"
    ],
    "synonyms": [
      "FCD type II",
      "cortical dysplasia, Taylor type",
      "focal cortical dysplasia, type II, somatic",
      "isolated focal cortical dysplasia type 2",
      "CDT",
      "FCD 2A",
      "FCD 2B",
      "FCDT",
      "FCORD2",
      "Fcd2",
      "cortical dysplasia of Taylor",
      "cortical dysplasia of Taylor with balloon cells",
      "cortical dysplasia of Taylor without balloon cells",
      "cortical dysplasia of Taylor, dysplasia only",
      "focal cortical dysplasia of Taylor",
      "focal cortical dysplasia of Taylor, type 2A",
      "focal cortical dysplasia of Taylor, type 2B",
      "focal cortical dysplasia type 2",
      "focal cortical dysplasia type II",
      "focal cortical dysplasia, type 2",
      "focal cortical dysplasia, type 2A",
      "focal cortical dysplasia, type 2B",
      "focal cortical dysplasia, type II"
    ],
    "categories": [
      {
        "ref": "MONDO:0005071",
        "name": "nervous system disorder"
      }
    ]
  },
  "isLeaf": false,
  "isRoot": false,
  "child_count": 2,
  "parents": [
    {
      "id": 18924,
      "label": "isolated focal cortical dysplasia",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        17471,
        24020
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "GARD:0016671",
          "MEDGEN:1645432",
          "NANDO:1200564",
          "Orphanet:65683",
          "SCTID:766710005",
          "UMLS:C4707795"
        ],
        "synonyms": [
          "epilepsy due to FCD"
        ],
        "categories": [
          {
            "ref": "MONDO:0005071",
            "name": "nervous system disorder"
          }
        ],
        "definition": "Isolated focal cortical dysplasia is a rare, genetic, non-syndromic cerebral malformation due to abnormal neuronal migration disorder characterized by variable-sized, focalized malformations located in any part(s) of the cerebral cortex, which manifests with drug-resistant epilepsy (usually leading to intellectual disability) and behavioral disturbances. Abnormal MRI findings (e.g. abnormal white and/or gray matter signal, blurred gray-white matter junction, localized volume loss, cortical thickening, abnormal gyral pattern, abnormal hippocampus) and variable histopathologic patterns are associated."
      },
      "child_count": 4,
      "reference_id": "MONDO:0019009"
    }
  ],
  "children": [
    {
      "id": 17477,
      "label": "isolated focal cortical dysplasia type IIa",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        12899
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "GARD:0017270",
          "MEDGEN:375876",
          "NANDO:1200568",
          "Orphanet:269001",
          "UMLS:C1846386"
        ],
        "synonyms": [
          "FCD type IIa"
        ],
        "categories": [
          {
            "ref": "MONDO:0005071",
            "name": "nervous system disorder"
          }
        ]
      },
      "child_count": 0,
      "reference_id": "MONDO:0017101"
    },
    {
      "id": 17478,
      "label": "isolated focal cortical dysplasia type IIb",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        12899
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "GARD:0017271",
          "MEDGEN:1842232",
          "NANDO:1200569",
          "Orphanet:269008",
          "UMLS:C5679768"
        ],
        "synonyms": [
          "FCD type IIb"
        ],
        "categories": [
          {
            "ref": "MONDO:0005071",
            "name": "nervous system disorder"
          }
        ]
      },
      "child_count": 0,
      "reference_id": "MONDO:0017102"
    }
  ],
  "roots": [
    {
      "id": 18924,
      "label": "isolated focal cortical dysplasia"
    }
  ]
}