{
  "id": 13075,
  "label": "parathyroid gland carcinoma",
  "model": {
    "label": "Mondo Disease Ontology (MONDO)",
    "source": 0
  },
  "type_id": 0,
  "reference_id": "MONDO:0012004",
  "properties": {
    "xrefs": [
      "DOID:1540",
      "EFO:1000456",
      "GARD:0007329",
      "MEDGEN:146361",
      "NCIT:C4906",
      "OMIM:608266",
      "ONCOTREE:PTHC",
      "Orphanet:143",
      "SCTID:255037004",
      "UMLS:C0687150"
    ],
    "synonyms": [
      "cancer of parathyroid gland",
      "cancer of the parathyroid gland",
      "malignant neoplasm of parathyroid gland",
      "malignant neoplasm of the parathyroid",
      "malignant tumour of parathyroid gland",
      "parathyroid cancer",
      "parathyroid gland cancer",
      "parathyroid gland neoplasm",
      "parathyroid neoplasm",
      "adenocarcinoma of parathyroid",
      "adenocarcinoma of parathyroid gland",
      "adenocarcinoma of the parathyroid",
      "adenocarcinoma of the parathyroid gland",
      "carcinoma of parathyroid",
      "carcinoma of parathyroid gland",
      "carcinoma of the parathyroid",
      "carcinoma of the parathyroid gland",
      "parathyroid adenocarcinoma",
      "parathyroid carcinoma",
      "parathyroid gland adenocarcinoma",
      "parathyroid gland carcinoma",
      "PRTC"
    ],
    "categories": [
      {
        "ref": "MONDO:0005151",
        "name": "endocrine system disorder"
      }
    ],
    "definition": "A very rare, slow-growing, clinically serious endocrine tumor that generally develops in mid-adulthood. PRTC presents as a palpable painless mass in the neck and causes severe hypercalcemia and related symptoms, non-specific gastrointestinal manifestations, as well as renal and bone complications related to primary hyperparathyroidism (nephrolithiasis, impaired renal function, osteoporosis, bone pain, and pathologic fractures, etc.). Some PRTCs are however non-functioning tumors."
  },
  "isLeaf": true,
  "isRoot": false,
  "child_count": 0,
  "parents": [
    {
      "id": 5714,
      "label": "hereditary disease",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        29382
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:630",
          "EFO:0000508",
          "ICD9:799.89",
          "MEDGEN:5527",
          "MESH:D030342",
          "NCIT:C3101",
          "SCTID:32895009",
          "UMLS:C0019247"
        ],
        "synonyms": [
          "genetic condition",
          "genetic disease",
          "genetic disorder",
          "hereditary disease",
          "hereditary disease or disorder",
          "hereditary diseases",
          "inherited disease",
          "inherited genetic disease",
          "molecular disease",
          "Mendelian disease",
          "familial disorder",
          "inborn disorder"
        ],
        "definition": "A disease that is caused by genetic modifications where those modifications are inherited from a parent's genome."
      },
      "child_count": 1925,
      "reference_id": "MONDO:0003847"
    },
    {
      "id": 6712,
      "label": "adenocarcinoma",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        6734,
        21312
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "CSP:2000-0386",
          "DOID:299",
          "EFO:0000228",
          "ICDO:8140/3",
          "MEDGEN:122",
          "MESH:D000230",
          "NCIT:C2852",
          "ONCOTREE:ADNOS",
          "SCTID:443961001",
          "UMLS:C0001418"
        ],
        "synonyms": [
          "adenocarcinoma",
          "adenocarcinoma NOS (morphologic abnormality)",
          "adenocarcinoma, malignant",
          "adenocarcinoma, no subtype (morphologic abnormality)",
          "adenocarcinomas",
          "ADNOS"
        ],
        "definition": "A common cancer characterized by the presence of malignant glandular cells. Morphologically, adenocarcinomas are classified according to the growth pattern (e.g., papillary, alveolar) or according to the secreting product (e.g., mucinous, serous). Representative examples of adenocarcinoma are ductal and lobular breast carcinoma, lung adenocarcinoma, renal cell carcinoma, hepatocellular carcinoma (hepatoma), colon adenocarcinoma, and prostate adenocarcinoma."
      },
      "child_count": 128,
      "reference_id": "MONDO:0004970"
    },
    {
      "id": 20493,
      "label": "malignant tumor of parathyroid gland",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        20310,
        20525
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "ICD10CM:C75.0",
          "ICD9:194.1",
          "MEDGEN:102283",
          "NCIT:C9322",
          "ONCOTREE:PTH",
          "SCTID:363481002",
          "UMLS:C0153653"
        ],
        "synonyms": [
          "cancer of parathyroid gland",
          "malignant neoplasm of parathyroid",
          "malignant neoplasm of parathyroid gland",
          "malignant neoplasm of the parathyroid",
          "malignant neoplasm of the parathyroid gland",
          "malignant parathyroid gland neoplasm",
          "malignant parathyroid gland tumor",
          "malignant parathyroid gland tumour",
          "malignant parathyroid neoplasm",
          "malignant parathyroid tumor",
          "malignant parathyroid tumour",
          "malignant tumor of parathyroid",
          "malignant tumor of the parathyroid",
          "malignant tumor of the parathyroid gland",
          "malignant tumour of parathyroid",
          "malignant tumour of the parathyroid",
          "malignant tumour of the parathyroid gland",
          "parathyroid cancer",
          "parathyroid gland cancer"
        ],
        "categories": [
          {
            "ref": "MONDO:0005151",
            "name": "endocrine system disorder"
          }
        ],
        "definition": "A cancer that involves the parathyroid gland."
      },
      "child_count": 2,
      "reference_id": "MONDO:0021311"
    }
  ],
  "children": [],
  "roots": [
    {
      "id": 5714,
      "label": "hereditary disease"
    },
    {
      "id": 6712,
      "label": "adenocarcinoma"
    },
    {
      "id": 20493,
      "label": "malignant tumor of parathyroid gland"
    }
  ]
}