{
  "id": 13192,
  "label": "familial avascular necrosis of femoral head",
  "model": {
    "label": "Mondo Disease Ontology (MONDO)",
    "source": 0
  },
  "type_id": 0,
  "reference_id": "MONDO:0012126",
  "properties": {
    "xrefs": [
      "GARD:0010914",
      "MEDGEN:909851",
      "MESH:D005271",
      "NANDO:1200373",
      "NCIT:C35480",
      "OMIMPS:608805",
      "Orphanet:86820",
      "SCTID:715657008",
      "UMLS:C4275066",
      "icd11.foundation:1216860745"
    ],
    "synonyms": [
      "aseptic Necrosis of femoral head",
      "aseptic Necrosis of head of femur",
      "familial osteonecrosis of the femoral head",
      "ANFH",
      "ANFH1",
      "avascular NECROSIS of femoral head, primary",
      "avascular NECROSIS of femoral head, primary, 1",
      "avascular Necrosis of femoral head, primary, 1",
      "familial avascular necrosis of the femoral head",
      "femoral head, aseptic Necrosis of",
      "femoral head, avascular Necrosis of",
      "ischaemic Necrosis of femoral head",
      "ischemic Necrosis of femoral head",
      "osteonecrosis of femoral head",
      "primary avascular necrosis of the femoral head"
    ],
    "categories": [
      {
        "ref": "MONDO:0002081",
        "name": "musculoskeletal system disorder"
      }
    ],
    "definition": "Avascular necrosis of femoral head (ANFH) is a severely disabling disease characterized by progressive groin pain, a limping gait, leg length discrepancy, collapse of the subchondral bone, limitation of hip function and eventual degeneration of the hip joint requiring total hip arthroplasty."
  },
  "isLeaf": false,
  "isRoot": false,
  "child_count": 2,
  "parents": [
    {
      "id": 18458,
      "label": "primary avascular necrosis",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        18453
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "GARD:0021664",
          "MEDGEN:1842421",
          "Orphanet:399302",
          "UMLS:C5680038"
        ],
        "synonyms": [
          "primary AVN"
        ],
        "categories": [
          {
            "ref": "MONDO:0002081",
            "name": "musculoskeletal system disorder"
          }
        ]
      },
      "child_count": 3,
      "reference_id": "MONDO:0018379"
    },
    {
      "id": 18462,
      "label": "osteonecrosis of genetic origin",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        5714,
        7060
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "GARD:0021667",
          "MEDGEN:1842788",
          "Orphanet:399380",
          "UMLS:C5680035"
        ],
        "synonyms": [
          "bone necrosis of genetic origin",
          "genetic osteonecrosis"
        ],
        "categories": [
          {
            "ref": "MONDO:0002081",
            "name": "musculoskeletal system disorder"
          }
        ],
        "definition": "An instance of osteonecrosis that is caused by a modification of the individual's genome."
      },
      "child_count": 24,
      "reference_id": "MONDO:0018383"
    }
  ],
  "children": [
    {
      "id": 23557,
      "label": "avascular necrosis of femoral head, primary, 1",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        13192,
        29221
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "GARD:0025946",
          "MEDGEN:1639295",
          "OMIM:608805",
          "UMLS:C4551562"
        ],
        "synonyms": [
          "avascular necrosis of femoral head, primary, 1",
          "avascular necrosis of the femoral head",
          "ANFH1",
          "Femoral head, avascular necrosis of",
          "femoral head, aseptic necrosis of",
          "ischaemic necrosis of femoral head",
          "ischemic necrosis of femoral head",
          "osteonecrosis of femoral head"
        ],
        "categories": [
          {
            "ref": "MONDO:0002081",
            "name": "musculoskeletal system disorder"
          },
          {
            "ref": "MONDO:0002254",
            "name": "syndromic disease"
          },
          {
            "ref": "MONDO:0003900",
            "name": "connective tissue disorder"
          }
        ]
      },
      "child_count": 0,
      "reference_id": "MONDO:0054550"
    },
    {
      "id": 23558,
      "label": "avascular necrosis of femoral head, primary, 2",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        13192
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "GARD:0025947",
          "MEDGEN:1386338",
          "OMIM:617383",
          "UMLS:C4479260"
        ],
        "synonyms": [
          "avascular necrosis of femoral head, primary, 2",
          "ANFH2"
        ],
        "categories": [
          {
            "ref": "MONDO:0002081",
            "name": "musculoskeletal system disorder"
          }
        ]
      },
      "child_count": 0,
      "reference_id": "MONDO:0054551"
    }
  ],
  "roots": [
    {
      "id": 18458,
      "label": "primary avascular necrosis"
    },
    {
      "id": 18462,
      "label": "osteonecrosis of genetic origin"
    }
  ]
}