{
  "id": 13206,
  "label": "orofacial cleft 5",
  "model": {
    "label": "Mondo Disease Ontology (MONDO)",
    "source": 0
  },
  "type_id": 0,
  "reference_id": "MONDO:0012142",
  "properties": {
    "xrefs": [
      "DOID:0080399",
      "GARD:0018305",
      "MEDGEN:373280",
      "MESH:C563843",
      "OMIM:608874",
      "UMLS:C1837210"
    ],
    "synonyms": [
      "MSX1 orofacial cleft",
      "orofacial cleft 5",
      "orofacial cleft caused by mutation in MSX1",
      "orofacial cleft type 5",
      "OFC5",
      "cleft lip with or without cleft palate, nonsyndromic, 5"
    ],
    "categories": [
      {
        "ref": "MONDO:0002081",
        "name": "musculoskeletal system disorder"
      }
    ],
    "definition": "Any orofacial cleft in which the cause of the disease is a mutation in the MSX1 gene."
  },
  "isLeaf": true,
  "isRoot": false,
  "child_count": 0,
  "parents": [
    {
      "id": 16269,
      "label": "cleft lip and alveolus",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        2863,
        20383
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "GARD:0016976",
          "ICD9:525.8",
          "MEDGEN:720590",
          "Orphanet:141291",
          "SCTID:373643003",
          "UMLS:C1298692",
          "icd11.foundation:1653169553"
        ],
        "categories": [
          {
            "ref": "MONDO:0002081",
            "name": "musculoskeletal system disorder"
          }
        ],
        "definition": "Cleft lip and alveolus is a fissure type embryopathy that involves the upper lip, nasal base and alveolar ridge in variable degrees."
      },
      "child_count": 2,
      "reference_id": "MONDO:0015420"
    },
    {
      "id": 16679,
      "label": "isolated cleft lip",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        6518,
        20383
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "GARD:0017091",
          "MEDGEN:40327",
          "MedDRA:10009259",
          "Orphanet:199302",
          "UMLS:C0008924",
          "icd11.foundation:172183323"
        ],
        "synonyms": [
          "isolated cleft lip (disease)",
          "nonsyndromic cleft lip (disease)"
        ],
        "categories": [
          {
            "ref": "MONDO:0002081",
            "name": "musculoskeletal system disorder"
          }
        ],
        "definition": "Isolated cleft lip is a fissure type embryopathy extending from the upper lip to the nasal base."
      },
      "child_count": 4,
      "reference_id": "MONDO:0016043"
    },
    {
      "id": 16680,
      "label": "cleft lip/palate",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        2863,
        20383
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "GARD:0017092",
          "ICD10CM:Q35-Q37",
          "ICD9:749.20",
          "ICD9:749.25",
          "MEDGEN:57640",
          "MedDRA:10009260",
          "Orphanet:199306",
          "SCTID:66948001",
          "UMLS:C0158646"
        ],
        "synonyms": [
          "FLP",
          "alveolar cleft lip and palate",
          "cleft lip and palate",
          "cleft lip-alveolus-palate syndrome"
        ],
        "categories": [
          {
            "ref": "MONDO:0002081",
            "name": "musculoskeletal system disorder"
          }
        ],
        "definition": "Cleft lip and palate is a fissure type embryopathy extending across the upper lip, nasal base, alveolar ridge and the hard and soft palate."
      },
      "child_count": 8,
      "reference_id": "MONDO:0016044"
    }
  ],
  "children": [],
  "roots": [
    {
      "id": 16269,
      "label": "cleft lip and alveolus"
    },
    {
      "id": 16679,
      "label": "isolated cleft lip"
    },
    {
      "id": 16680,
      "label": "cleft lip/palate"
    }
  ]
}