{
  "id": 13218,
  "label": "choanal atresia",
  "model": {
    "label": "Mondo Disease Ontology (MONDO)",
    "source": 0
  },
  "type_id": 0,
  "reference_id": "MONDO:0012155",
  "properties": {
    "xrefs": [
      "DOID:9574",
      "GARD:0016951",
      "ICD10CM:Q30.0",
      "ICD9:748.0",
      "MEDGEN:3395",
      "MESH:D002754",
      "MedDRA:10008587",
      "OMIM:608911",
      "Orphanet:137914",
      "SCTID:204508009",
      "UMLS:C0008297",
      "icd11.foundation:2099486655"
    ],
    "synonyms": [
      "atresia of nares",
      "PCA",
      "choanal atresia, POSTERIOR"
    ],
    "categories": [
      {
        "ref": "MONDO:0005087",
        "name": "respiratory system disorder"
      },
      {
        "ref": "MONDO:0024623",
        "name": "otorhinolaryngologic disease"
      }
    ],
    "definition": "Choanal atresia (CA) is a congenital anomaly of the posterior nasal airway characterized by the obstruction of one (unilateral) or both (bilateral) choanal aperture(s), with clinical manifestations ranging from acute respiratory distress to chronic nasal obstruction."
  },
  "isLeaf": false,
  "isRoot": false,
  "child_count": 2,
  "parents": [
    {
      "id": 4349,
      "label": "nasal cavity disorder",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        4522,
        6623
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:2163",
          "MEDGEN:137929",
          "NCIT:C27102",
          "SCTID:232340005",
          "UMLS:C0339820"
        ],
        "synonyms": [
          "disease of nasal cavity",
          "disease or disorder of nasal cavity",
          "disorder of nasal cavity",
          "nasal cavity disease",
          "nasal cavity disease or disorder",
          "nasal cavity disorder"
        ],
        "categories": [
          {
            "ref": "MONDO:0005087",
            "name": "respiratory system disorder"
          },
          {
            "ref": "MONDO:0024623",
            "name": "otorhinolaryngologic disease"
          }
        ],
        "definition": "A disease involving the nasal cavity."
      },
      "child_count": 10,
      "reference_id": "MONDO:0002232"
    },
    {
      "id": 18718,
      "label": "hereditary otorhinolaryngologic disease",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        5714,
        21538
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "GARD:0021935",
          "MEDGEN:1842579",
          "Orphanet:466084",
          "UMLS:C5681130"
        ],
        "synonyms": [
          "genetic otorhinolaryngologic disease"
        ],
        "categories": [
          {
            "ref": "MONDO:0024623",
            "name": "otorhinolaryngologic disease"
          }
        ],
        "definition": "An instance of otorhinolaryngologic disease that is caused by a modification of the individual's genome."
      },
      "child_count": 42,
      "reference_id": "MONDO:0018751"
    }
  ],
  "children": [
    {
      "id": 16189,
      "label": "choanal atresia, unilateral",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        13218
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "GARD:0019889",
          "MEDGEN:1843076",
          "Orphanet:137917",
          "UMLS:C5680630",
          "icd11.foundation:1247369366"
        ],
        "categories": [
          {
            "ref": "MONDO:0005087",
            "name": "respiratory system disorder"
          },
          {
            "ref": "MONDO:0024623",
            "name": "otorhinolaryngologic disease"
          }
        ],
        "definition": "Unilateral choanal atresia is a, usually sporadic, congenital anomaly that is more commonly seen in females than in males (2:1), where the nose is blocked by bony or soft tissue formed during embryologic development on only one side (more commonly on the right side) and which is characterized by nasal obstruction and rhinorrhea, usually presenting at birth but that may go undetected until a respiratory infection aggravates the condition."
      },
      "child_count": 0,
      "reference_id": "MONDO:0015312"
    },
    {
      "id": 16190,
      "label": "choanal atresia, bilateral",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        13218
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "GARD:0019890",
          "MEDGEN:870857",
          "Orphanet:137920",
          "UMLS:C4025317",
          "icd11.foundation:1138913171"
        ],
        "categories": [
          {
            "ref": "MONDO:0005087",
            "name": "respiratory system disorder"
          },
          {
            "ref": "MONDO:0024623",
            "name": "otorhinolaryngologic disease"
          }
        ],
        "definition": "Bilateral choanal atresia is a congenital anomaly that is usually sporadic (but some familial cases have been reported), is more commonly seen in females than in males (2:1), and where the nose is blocked on both sides by bony or soft tissue formed during embryological development. It is characterized by respiratory distress relieved by crying and rhinorrhea that presents at birth."
      },
      "child_count": 0,
      "reference_id": "MONDO:0015313"
    }
  ],
  "roots": [
    {
      "id": 4349,
      "label": "nasal cavity disorder"
    },
    {
      "id": 18718,
      "label": "hereditary otorhinolaryngologic disease"
    }
  ]
}