{
  "id": 13266,
  "label": "autosomal dominant striatal neurodegeneration type 1",
  "model": {
    "label": "Mondo Disease Ontology (MONDO)",
    "source": 0
  },
  "type_id": 0,
  "reference_id": "MONDO:0012205",
  "properties": {
    "xrefs": [
      "GARD:0024853",
      "MEDGEN:934775",
      "OMIM:609161",
      "SCTID:725392005",
      "UMLS:C4310808"
    ],
    "synonyms": [
      "ADSD1",
      "PDE8B striatal degeneration, autosomal dominant",
      "striatal Degeneration, autosomal dominant 1",
      "striatal degeneration, autosomal dominant 1",
      "striatal degeneration, autosomal dominant caused by mutation in PDE8B",
      "ADSD",
      "autosomal dominant striatal neurodegeneration",
      "striatal degeneration, autosomal dominant"
    ],
    "categories": [
      {
        "ref": "MONDO:0005071",
        "name": "nervous system disorder"
      }
    ],
    "definition": "Autosomal dominant striatal degeneration is a neurologic disorder characterized by variable movement abnormalities due to dysfunction in the striatal part of the basal ganglia."
  },
  "isLeaf": true,
  "isRoot": false,
  "child_count": 0,
  "parents": [
    {
      "id": 2770,
      "label": "striatal degeneration, autosomal dominant",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        5100
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "GARD:0017146",
          "MEDGEN:322971",
          "MESH:C563783",
          "OMIMPS:609161",
          "Orphanet:228169",
          "UMLS:C1836694"
        ],
        "synonyms": [
          "ADSD",
          "autosomal dominant striatal neurodegeneration"
        ],
        "categories": [
          {
            "ref": "MONDO:0005071",
            "name": "nervous system disorder"
          }
        ],
        "definition": "An adult-onset movement disorder characterized by bradykinesia, dysarthria and muscle rigidity."
      },
      "child_count": 2,
      "reference_id": "MONDO:0000211"
    },
    {
      "id": 20335,
      "label": "parkinsonian disorder",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        5849
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:0080855",
          "MEDGEN:66079",
          "MESH:D020734",
          "UMLS:C0242422"
        ],
        "categories": [
          {
            "ref": "MONDO:0005071",
            "name": "nervous system disorder"
          }
        ],
        "definition": "A group of disorders which feature impaired motor control characterized by bradykinesia, MUSCLE RIGIDITY; TREMOR; and postural instability. Parkinsonian diseases are generally divided into primary parkinsonism (see PARKINSON DISEASE), secondary parkinsonism (see PARKINSON DISEASE, SECONDARY) and inherited forms. These conditions are associated with dysfunction of dopaminergic or closely related motor integration neuronal pathways in the BASAL GANGLIA."
      },
      "child_count": 21,
      "reference_id": "MONDO:0021095"
    }
  ],
  "children": [],
  "roots": [
    {
      "id": 2770,
      "label": "striatal degeneration, autosomal dominant"
    },
    {
      "id": 20335,
      "label": "parkinsonian disorder"
    }
  ]
}