{
  "id": 13620,
  "label": "vesicoureteral reflux 2",
  "model": {
    "label": "Mondo Disease Ontology (MONDO)",
    "source": 0
  },
  "type_id": 0,
  "reference_id": "MONDO:0012573",
  "properties": {
    "xrefs": [
      "GARD:0018419",
      "MEDGEN:370270",
      "MESH:C567053",
      "OMIM:610878",
      "UMLS:C1970483"
    ],
    "synonyms": [
      "ROBO2 vesicoureteral reflux (disease)",
      "vesicoureteral reflux (disease) caused by mutation in ROBO2",
      "vesicoureteral reflux 2",
      "vesicoureteral reflux type 2",
      "VUR2"
    ],
    "categories": [
      {
        "ref": "MONDO:0002118",
        "name": "urinary system disorder"
      }
    ],
    "definition": "Any vesicoureteral reflux in which the cause of the disease is a mutation in the ROBO2 gene."
  },
  "isLeaf": true,
  "isRoot": false,
  "child_count": 0,
  "parents": [
    {
      "id": 17648,
      "label": "familial vesicoureteral reflux",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        5714,
        7598
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "GARD:0017323",
          "MEDGEN:1637583",
          "OMIMPS:193000",
          "Orphanet:289365",
          "SCTID:763716008",
          "UMLS:C4706552"
        ],
        "synonyms": [
          "familial VUR",
          "hereditary vesicoureteral reflux (disease)"
        ],
        "categories": [
          {
            "ref": "MONDO:0002118",
            "name": "urinary system disorder"
          }
        ],
        "definition": "Familial vesicoureteral reflux is a rare, non-syndromic urogenital tract malformation characterized by the familial occurrence of retrograde flow of urine from the bladder into the ureter and sometimes the kidneys. Patients may be asymptomatic or may present with recurrent, sometimes febrile, urinary tract infections that, in case of acute pyelonephritis, may lead to serious complications (renal scarring, hypertension, renal failure). Spontaneous resolution of the disorder is possible."
      },
      "child_count": 18,
      "reference_id": "MONDO:0017329"
    }
  ],
  "children": [],
  "roots": [
    {
      "id": 17648,
      "label": "familial vesicoureteral reflux"
    }
  ]
}