{
  "id": 14223,
  "label": "factor XIII, A subunit, deficiency of",
  "model": {
    "label": "Mondo Disease Ontology (MONDO)",
    "source": 0
  },
  "type_id": 0,
  "reference_id": "MONDO:0013187",
  "properties": {
    "xrefs": [
      "GARD:0015633",
      "MEDGEN:442497",
      "MESH:C567691",
      "OMIM:613225",
      "SCTID:439455002",
      "UMLS:C2750514"
    ],
    "synonyms": [
      "factor XIII, A subunit, deficiency of",
      "factor XIIIA deficiency",
      "hereditary factor XIII A subunit deficiency",
      "hereditary factor XIII alpha subunit deficiency",
      "hereditary factor XIII type II deficiency"
    ],
    "categories": [
      {
        "ref": "MONDO:0005570",
        "name": "hematologic disorder"
      }
    ]
  },
  "isLeaf": true,
  "isRoot": false,
  "child_count": 0,
  "parents": [
    {
      "id": 18203,
      "label": "congenital factor XIII deficiency",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        4358,
        4360,
        10564
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:2211",
          "GARD:0010766",
          "ICD9:286.3",
          "MEDGEN:4639",
          "NANDO:2200681",
          "NCIT:C131633",
          "Orphanet:331",
          "SCTID:50189006",
          "UMLS:C0015530"
        ],
        "synonyms": [
          "fibrin-stabilizing factor deficiency",
          "factor XIII deficiency",
          "fibrin stabilising factor deficiency",
          "fibrin stabilizing factor deficiency"
        ],
        "categories": [
          {
            "ref": "MONDO:0005570",
            "name": "hematologic disorder"
          }
        ],
        "definition": "Congenital factor XIII deficiency is an inherited bleeding disorder due to reduced levels and activity of factor XIII (FXIII) and characterized by hemorrhagic diathesis frequently associated with spontaneous abortions and defective wound healing. Factor XIII deficiency is one of the most rare coagulation factor deficiencies."
      },
      "child_count": 6,
      "reference_id": "MONDO:0018029"
    },
    {
      "id": 20411,
      "label": "inherited blood coagulation disorder",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        3738,
        5714
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:2214",
          "GARD:0020319",
          "MEDGEN:163105",
          "MESH:D025861",
          "Orphanet:183654",
          "UMLS:C0852077"
        ],
        "synonyms": [
          "coagulation disorder, hereditary",
          "coagulation disorder, inherited",
          "coagulation disorders, hereditary",
          "coagulation disorders, inherited",
          "hereditary blood coagulation disease",
          "hereditary blood coagulation disorders",
          "hereditary coagulation disorder",
          "hereditary coagulation disorders",
          "inherited blood coagulation disorders",
          "inherited coagulation disorder",
          "inherited coagulation disorders",
          "rare genetic coagulation disorder",
          "inherited blood coagulation disease"
        ],
        "categories": [
          {
            "ref": "MONDO:0005570",
            "name": "hematologic disorder"
          }
        ],
        "definition": "Hemorrhagic and thrombotic disorders that occur as a consequence of inherited abnormalities in blood coagulation."
      },
      "child_count": 78,
      "reference_id": "MONDO:0021181"
    }
  ],
  "children": [],
  "roots": [
    {
      "id": 18203,
      "label": "congenital factor XIII deficiency"
    },
    {
      "id": 20411,
      "label": "inherited blood coagulation disorder"
    }
  ]
}