{
  "id": 14331,
  "label": "myeloid neoplasm associated with FGFR1 rearrangement",
  "model": {
    "label": "Mondo Disease Ontology (MONDO)",
    "source": 0
  },
  "type_id": 0,
  "reference_id": "MONDO:0013296",
  "properties": {
    "xrefs": [
      "DOID:0080167",
      "GARD:0017043",
      "ICDO:9967/3",
      "MEDGEN:462123",
      "NCIT:C84277",
      "OMIM:613523",
      "ONCOTREE:MLNFGFR1",
      "Orphanet:168953",
      "UMLS:C3150773",
      "icd11.foundation:2019647878"
    ],
    "synonyms": [
      "8p11 myeloproliferative syndrome",
      "8p11 stem cell leukemia/lymphoma syndrome",
      "8p11 stem cell syndrome",
      "chromosome 8p11 myeloproliferative syndrome",
      "myeloid and lymphoid neoplasms associated with FGFR1 abnormalities",
      "myeloid and lymphoid neoplasms with FGFR1 rearrangement",
      "myeloid/lymphoid neoplasm associated with FGFR1 rearrangement",
      "myeloid/lymphoid neoplasms with FGFR1 rearrangement",
      "stem cell leukemia/lymphoma"
    ],
    "categories": [
      {
        "ref": "MONDO:0005570",
        "name": "hematologic disorder"
      }
    ],
    "definition": "Hematologic neoplasms characterized by the rearrangement of the FGFR1 gene, resulting in translocations with an 8p11 breakpoint. Patients present with a myeloproliferative neoplasm, acute myeloid leukemia, lymphoblastic lymphoma/leukemia of T or B-cell lineage, or acute leukemia of mixed phenotype."
  },
  "isLeaf": true,
  "isRoot": false,
  "child_count": 0,
  "parents": [
    {
      "id": 16453,
      "label": "myeloid/lymphoid neoplasms associated with eosinophilia and abnormality of PDGFRA, PDGFRB, FGFR1 or JAK2",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        16513,
        23467
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:0080164",
          "GARD:0020105",
          "MEDGEN:417664",
          "NCIT:C84270",
          "Orphanet:168943",
          "UMLS:C2827356"
        ],
        "synonyms": [
          "myeloid and lymphoid neoplasms with eosinophilia and abnormalities of PDGFRA, PDGFRB, and FGFR1",
          "myeloid and lymphoid neoplasms with eosinophilia and abnormalities of PDGFRA, PDGFRB, or FGFR1",
          "myeloid and lymphoid neoplasms with eosinophilia and rearrangement of PDGFRA, PDGFRB, or FGFR1, or with PCM1-JAK2",
          "myeloid/lymphoid neoplasms associated with eosinophilia and abnormality of PDGFRA, PDGFRB, FGFR1 or JAK2",
          "myeloid/lymphoid neoplasms with eosinophilia and gene rearrangement",
          "myeloid/lymphoid neoplasms with eosinophilia and rearrangement of PDGFRA, PDGFRB, or FGFR1, or with PCM1-JAK2"
        ],
        "categories": [
          {
            "ref": "MONDO:0005570",
            "name": "hematologic disorder"
          }
        ]
      },
      "child_count": 8,
      "reference_id": "MONDO:0015688"
    }
  ],
  "children": [],
  "roots": [
    {
      "id": 16453,
      "label": "myeloid/lymphoid neoplasms associated with eosinophilia and abnormality of PDGFRA, PDGFRB, FGFR1 or JAK2"
    }
  ]
}