{
  "id": 14336,
  "label": "aromatase deficiency",
  "model": {
    "label": "Mondo Disease Ontology (MONDO)",
    "source": 0
  },
  "type_id": 0,
  "reference_id": "MONDO:0013301",
  "properties": {
    "xrefs": [
      "GARD:0000365",
      "MEDGEN:743307",
      "MESH:C537436",
      "NCIT:C120144",
      "OMIM:613546",
      "Orphanet:91",
      "UMLS:C1960539",
      "icd11.foundation:260189446"
    ],
    "synonyms": [
      "aromatase deficiency",
      "congenital estrogen deficiency",
      "congenital oestrogen deficiency",
      "pseudohermaphroditism, female, due to placental aromatase deficiency"
    ],
    "categories": [
      {
        "ref": "MONDO:0005039",
        "name": "reproductive system disorder"
      },
      {
        "ref": "MONDO:0005151",
        "name": "endocrine system disorder"
      }
    ],
    "definition": "Aromatase deficiency disrupts the synthesis of estradiol, resulting in hirsutism of mothers during gestation of an affected child; pseudohermaphroditism and virilization in women; and tall stature, osteoporosis and obesity in men."
  },
  "isLeaf": true,
  "isRoot": false,
  "child_count": 0,
  "parents": [
    {
      "id": 19578,
      "label": "inherited primary ovarian failure",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        5714,
        7067,
        16330,
        20362
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "GARD:0019294",
          "MEDGEN:443920",
          "OMIMPS:311360",
          "Orphanet:95710",
          "UMLS:C2930861"
        ],
        "synonyms": [
          "hereditary primary ovarian failure",
          "inherited POI",
          "inherited premature ovarian failure",
          "inherited primary ovarian insufficiency",
          "non-acquired premature ovarian failure"
        ],
        "categories": [
          {
            "ref": "MONDO:0005039",
            "name": "reproductive system disorder"
          },
          {
            "ref": "MONDO:0005151",
            "name": "endocrine system disorder"
          }
        ],
        "definition": "An instance of primary ovarian failure that is caused by an inherited modification of the individual's genome."
      },
      "child_count": 164,
      "reference_id": "MONDO:0019852"
    },
    {
      "id": 21520,
      "label": "pregnancy disorder",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        24401
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "EFO:0009682",
          "MEDGEN:56248",
          "MESH:D011248",
          "NCIT:C35169",
          "SCTID:173300003",
          "UMLS:C0151864"
        ],
        "synonyms": [
          "complication of pregnancy or childbirth",
          "disorder of pregnancy",
          "disorder of pregnancy, childbirth, or puerperium",
          "pregnancy disease",
          "pregnancy disorder",
          "Complications, pregnancy",
          "complication, pregnancy",
          "pregnancy complication"
        ],
        "definition": "A disorder that is related to pregnancy. Representative examples include ectopic pregnancy, toxemia of pregnancy, and gestational trophoblastic tumor."
      },
      "child_count": 29,
      "reference_id": "MONDO:0024575"
    }
  ],
  "children": [],
  "roots": [
    {
      "id": 19578,
      "label": "inherited primary ovarian failure"
    },
    {
      "id": 21520,
      "label": "pregnancy disorder"
    }
  ]
}