{
  "id": 14487,
  "label": "constitutional megaloblastic anemia with severe neurologic disease",
  "model": {
    "label": "Mondo Disease Ontology (MONDO)",
    "source": 0
  },
  "type_id": 0,
  "reference_id": "MONDO:0013456",
  "properties": {
    "xrefs": [
      "GARD:0011000",
      "MEDGEN:462555",
      "MESH:C565095",
      "OMIM:613839",
      "Orphanet:319651",
      "SCTID:124178006",
      "UMLS:C3151205"
    ],
    "synonyms": [
      "DHFR deficiency",
      "dihydrofolate reductase deficiency",
      "megaloblastic anaemia due to dihydrofolate reductase deficiency",
      "megaloblastic anemia due to dihydrofolate reductase deficiency"
    ],
    "categories": [
      {
        "ref": "MONDO:0005570",
        "name": "hematologic disorder"
      }
    ]
  },
  "isLeaf": true,
  "isRoot": false,
  "child_count": 0,
  "parents": [
    {
      "id": 3888,
      "label": "megaloblastic anemia",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        4395
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:13382",
          "HP:0001889",
          "ICD9:281.3",
          "MEDGEN:1527",
          "NANDO:2100176",
          "NANDO:2200612",
          "NCIT:C34382",
          "SCTID:53165003",
          "UMLS:C0002888"
        ],
        "synonyms": [
          "megaloblastic anaemia (disease)",
          "megaloblastic anemia",
          "megaloblastic anemia (disease)"
        ],
        "categories": [
          {
            "ref": "MONDO:0005570",
            "name": "hematologic disorder"
          }
        ],
        "definition": "Anemia characterized by the presence of unusually large erythroblasts in the bone marrow called megaloblasts. It is usually caused by vitamin B12 or folic acid deficiency. Other causes include toxins and drugs."
      },
      "child_count": 6,
      "reference_id": "MONDO:0001700"
    },
    {
      "id": 17107,
      "label": "hereditary anemia",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        3835,
        5714
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "GARD:0020669",
          "MEDGEN:1842172",
          "Orphanet:248296",
          "UMLS:C5680695"
        ],
        "synonyms": [
          "constitutional deficiency anemia",
          "constitutional rare deficiency anaemia",
          "constitutional rare deficiency anemia",
          "inherited deficiency anemia"
        ],
        "categories": [
          {
            "ref": "MONDO:0005570",
            "name": "hematologic disorder"
          }
        ]
      },
      "child_count": 28,
      "reference_id": "MONDO:0016624"
    },
    {
      "id": 17632,
      "label": "disorder of folate metabolism and transport",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        17984
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "GARD:0021131",
          "MEDGEN:1842423",
          "Orphanet:285657",
          "UMLS:C5681010",
          "icd11.foundation:2081529009"
        ]
      },
      "child_count": 7,
      "reference_id": "MONDO:0017313"
    }
  ],
  "children": [],
  "roots": [
    {
      "id": 3888,
      "label": "megaloblastic anemia"
    },
    {
      "id": 17107,
      "label": "hereditary anemia"
    },
    {
      "id": 17632,
      "label": "disorder of folate metabolism and transport"
    }
  ]
}