{
  "id": 14686,
  "label": "Barrett esophagus",
  "model": {
    "label": "Mondo Disease Ontology (MONDO)",
    "source": 0
  },
  "type_id": 0,
  "reference_id": "MONDO:0013662",
  "properties": {
    "xrefs": [
      "DOID:9206",
      "EFO:0000280",
      "ICD10CM:K22.7",
      "ICD9:530.85",
      "MEDGEN:2551",
      "MESH:D001471",
      "NCIT:C2891",
      "OMIM:614266",
      "Orphanet:1232",
      "SCTID:196609006",
      "UMLS:C0004763"
    ],
    "synonyms": [
      "BE",
      "Barrett esophagus",
      "Barrett esophagus/esophageal adenocarcinoma",
      "Barrett's esophagus",
      "Barrett's oesophagus with esophagitis",
      "Barrett's ulcer of oesophagus",
      "CELLO",
      "CLE",
      "cello",
      "columnar epithelial-lined Lower esophagus",
      "columnar epithelial-lined Lower oesophagus",
      "columnar-lined esophagus",
      "columnar-lined oesophagus",
      "Barrett metaplasia",
      "adenocarcinoma of esophagus",
      "adenocarcinoma of oesophagus"
    ],
    "categories": [
      {
        "ref": "MONDO:0004335",
        "name": "digestive system disorder"
      }
    ],
    "definition": "Esophageal lesion lined with columnar metaplastic epithelium which is flat or villiform. Barrett epithelium is characterized by two different types of cells: goblet cells and columnar cells. The symptomatology of Barrett esophagus is that of gastro-esophageal reflux. It is the precursor of most esophageal adenocarcinomas. (WHO)"
  },
  "isLeaf": true,
  "isRoot": false,
  "child_count": 0,
  "parents": [
    {
      "id": 5629,
      "label": "esophageal disorder",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        23495
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:6050",
          "EFO:0009544",
          "ICD9:530",
          "ICD9:530.2",
          "ICD9:530.20",
          "ICD9:530.9",
          "MEDGEN:8693",
          "MESH:D004935",
          "NCIT:C3027",
          "SCTID:30811009",
          "SCTID:37657006",
          "UMLS:C0014852",
          "icd11.foundation:1594312948"
        ],
        "synonyms": [
          "disease of esophagus",
          "disease of oesophagus",
          "disease or disorder of esophagus",
          "disease or disorder of oesophagus",
          "disorder of esophagus",
          "disorder of oesophagus",
          "esophageal disorder",
          "esophagus disease",
          "esophagus disease or disorder",
          "oesophagus disease",
          "oesophagus disease or disorder",
          "esophageal ulcer"
        ],
        "categories": [
          {
            "ref": "MONDO:0004335",
            "name": "digestive system disorder"
          }
        ],
        "definition": "A non-neoplastic or neoplastic disorder that affects the esophagus. Representative examples of non-neoplastic disorders include esophagitis and esophageal ulcer. Representative examples of neoplastic disorders include carcinomas, lymphomas, and melanomas."
      },
      "child_count": 20,
      "reference_id": "MONDO:0003749"
    }
  ],
  "children": [],
  "roots": [
    {
      "id": 5629,
      "label": "esophageal disorder"
    }
  ]
}