{
  "id": 14746,
  "label": "colorectal cancer, hereditary nonpolyposis, type 7",
  "model": {
    "label": "Mondo Disease Ontology (MONDO)",
    "source": 0
  },
  "type_id": 0,
  "reference_id": "MONDO:0013725",
  "properties": {
    "xrefs": [
      "DOID:0070276",
      "GARD:0015799",
      "MEDGEN:346893",
      "MESH:C565777",
      "OMIM:614385",
      "UMLS:C1858380"
    ],
    "synonyms": [
      "MLH3 hereditary nonpolyposis colon cancer",
      "colorectal cancer, hereditary nonpolyposis, type 7",
      "hereditary nonpolyposis colon cancer caused by mutation in MLH3",
      "HNPCC7"
    ],
    "categories": [
      {
        "ref": "MONDO:0002254",
        "name": "syndromic disease"
      },
      {
        "ref": "MONDO:0004335",
        "name": "digestive system disorder"
      }
    ],
    "definition": "Any hereditary nonpolyposis colon cancer in which the cause of the disease is a mutation in the MLH3 gene."
  },
  "isLeaf": true,
  "isRoot": false,
  "child_count": 0,
  "parents": [
    {
      "id": 2903,
      "label": "autosomal dominant disease",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        2905
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:0050736",
          "ICD9:758.5",
          "MEDGEN:539206",
          "SCTID:11164009",
          "UMLS:C0265385"
        ],
        "synonyms": [
          "autosomal dominant disease or disorder",
          "autosomal dominant hereditary disorder",
          "autosomal dominant inherited disorder",
          "disease or disorder, autosomal dominant",
          "disease, autosomal dominant"
        ],
        "definition": "Autosomal dominant form of disease."
      },
      "child_count": 192,
      "reference_id": "MONDO:0000426"
    },
    {
      "id": 18627,
      "label": "hereditary nonpolyposis colon cancer",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        16218,
        21140
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "GARD:0025132",
          "MEDGEN:232602",
          "NCIT:C120083",
          "OMIMPS:120435",
          "Orphanet:443909",
          "SCTID:315058005",
          "UMLS:C1333990",
          "icd11.foundation:8113015"
        ],
        "synonyms": [
          "HNPCC",
          "Hereditary nonpolyposis colorectal cancer (HNPCC)",
          "colorectal cancer, hereditary nonpolyposis",
          "familial nonpolyposis colon cancer",
          "familial nonpolyposis colorectal cancer",
          "hereditary nonpolyposis colon cancer",
          "hereditary nonpolyposis colorectal cancer"
        ],
        "categories": [
          {
            "ref": "MONDO:0002254",
            "name": "syndromic disease"
          },
          {
            "ref": "MONDO:0004335",
            "name": "digestive system disorder"
          }
        ],
        "definition": "A cancer-predisposing condition characterized by the development of colorectal cancer not associated with colorectal polyposis, endometrial cancer, and various other cancers (such as malignant epithelial tumor of ovary, gastric, biliary tract, small bowel, and urinary tract cancer) that are frequently diagnosed at an early age."
      },
      "child_count": 10,
      "reference_id": "MONDO:0018630"
    }
  ],
  "children": [],
  "roots": [
    {
      "id": 2903,
      "label": "autosomal dominant disease"
    },
    {
      "id": 18627,
      "label": "hereditary nonpolyposis colon cancer"
    }
  ]
}