{
  "id": 15082,
  "label": "dilated cardiomyopathy 1II",
  "model": {
    "label": "Mondo Disease Ontology (MONDO)",
    "source": 0
  },
  "type_id": 0,
  "reference_id": "MONDO:0014073",
  "properties": {
    "xrefs": [
      "DOID:0110450",
      "GARD:0015916",
      "MEDGEN:767563",
      "OMIM:615184",
      "UMLS:C3554649"
    ],
    "synonyms": [
      "CMD1II",
      "CRYAB familial isolated dilated cardiomyopathy",
      "cardiomyopathy, dilated, type 1II",
      "dilated cardiomyopathy type 1II",
      "familial isolated dilated cardiomyopathy caused by mutation in CRYAB",
      "cardiomyopathy, dilated, 1II"
    ],
    "categories": [
      {
        "ref": "MONDO:0002081",
        "name": "musculoskeletal system disorder"
      },
      {
        "ref": "MONDO:0002254",
        "name": "syndromic disease"
      },
      {
        "ref": "MONDO:0004995",
        "name": "cardiovascular disorder"
      }
    ],
    "definition": "Any familial isolated dilated cardiomyopathy in which the cause of the disease is a mutation in the CRYAB gene."
  },
  "isLeaf": true,
  "isRoot": false,
  "child_count": 0,
  "parents": [
    {
      "id": 24709,
      "label": "familial isolated dilated cardiomyopathy",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        16878
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "GARD:0027293",
          "MEDGEN:1826005",
          "Orphanet:154",
          "UMLS:C5679590",
          "icd11.foundation:949016860"
        ],
        "synonyms": [
          "familial isolated dilated cardiomyopathy",
          "familial or idiopathic dilated cardiomyopathy"
        ],
        "categories": [
          {
            "ref": "MONDO:0002081",
            "name": "musculoskeletal system disorder"
          },
          {
            "ref": "MONDO:0004995",
            "name": "cardiovascular disorder"
          }
        ],
        "definition": "A rare familial cardiomyopathy characterized by the dilation of left ventricle and progressively impairing of systolic ventricular function, in the absence of abnormal loading conditions or coronary artery disease sufficient to cause global systolic impairment. The disease may cause heart failure or arrhythmia. The disease is isolated when no additional atypical cardiac or extracardiac manifestations are present."
      },
      "child_count": 45,
      "reference_id": "MONDO:0700335"
    },
    {
      "id": 29370,
      "label": "CRYAB-related myofibrillar myopathy-cataract-cardiomyopathy spectrum disorder",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        4370,
        5714
      ],
      "type_id": 0,
      "properties": {
        "synonyms": [
          "CRYAB-related myofibrillar myopathy-cataract-cardiomyopathy spectrum disorder",
          "alpha-B crystallinopathy"
        ],
        "categories": [
          {
            "ref": "MONDO:0002254",
            "name": "syndromic disease"
          }
        ],
        "definition": "A syndromic disease caused by a variation in the CRYAB gene, and characterized by a spectrum of phenotypes including cardiomyopathy, cataract, and/or myopathy."
      },
      "child_count": 6,
      "reference_id": "MONDO:1060212"
    }
  ],
  "children": [],
  "roots": [
    {
      "id": 24709,
      "label": "familial isolated dilated cardiomyopathy"
    },
    {
      "id": 29370,
      "label": "CRYAB-related myofibrillar myopathy-cataract-cardiomyopathy spectrum disorder"
    }
  ]
}