{
  "id": 15344,
  "label": "female infertility due to zona pellucida defect",
  "model": {
    "label": "Mondo Disease Ontology (MONDO)",
    "source": 0
  },
  "type_id": 0,
  "reference_id": "MONDO:0014342",
  "properties": {
    "xrefs": [
      "GARD:0017675",
      "MEDGEN:862728",
      "OMIM:615774",
      "Orphanet:404466",
      "UMLS:C4014291"
    ],
    "synonyms": [
      "OOMD",
      "OOMD1",
      "oocyte maturation defect",
      "oocyte maturation defect 1"
    ],
    "categories": [
      {
        "ref": "MONDO:0005039",
        "name": "reproductive system disorder"
      }
    ],
    "definition": "Female infertility due to zona pellucida defect is a rare, genetic, female infertility disorder characterized by the presence of abnormal oocytes that lack a zona pellucida. Affected individuals are unable to conceive despite having normal menstrual cycles and sex hormone levels, as well as no obstructions in the fallopian tubes or defects of the uterus or adnexa."
  },
  "isLeaf": true,
  "isRoot": false,
  "child_count": 0,
  "parents": [
    {
      "id": 15758,
      "label": "inherited oocyte maturation defect",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        5714,
        6779
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "OMIMPS:615774"
        ],
        "synonyms": [
          "oocyte maturation defect",
          "OOMD"
        ],
        "categories": [
          {
            "ref": "MONDO:0005039",
            "name": "reproductive system disorder"
          }
        ]
      },
      "child_count": 48,
      "reference_id": "MONDO:0014769"
    },
    {
      "id": 20362,
      "label": "female infertility",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        4379,
        6779
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "EFO:0008560",
          "ICD10CM:N97",
          "ICD10WHO:N97",
          "ICD9:628.8",
          "ICD9:628.9",
          "MEDGEN:5795",
          "MESH:D007247",
          "SCTID:6738008",
          "UMLS:C0021361",
          "icd11.foundation:1237004558"
        ],
        "synonyms": [
          "female infertility",
          "female reproductive system infertility",
          "female reproductive system infertility disorder",
          "infertility disorder of female reproductive system",
          "female sterility",
          "female sub-fertility",
          "female subfertility",
          "postpartum sterility",
          "sterility, female",
          "sterility, postpartum",
          "sub fertility, female",
          "sub-fertility, female",
          "subfertility, female"
        ],
        "categories": [
          {
            "ref": "MONDO:0005039",
            "name": "reproductive system disorder"
          }
        ],
        "definition": "Diminished or absent ability of a female to achieve conception."
      },
      "child_count": 8,
      "reference_id": "MONDO:0021124"
    }
  ],
  "children": [],
  "roots": [
    {
      "id": 15758,
      "label": "inherited oocyte maturation defect"
    },
    {
      "id": 20362,
      "label": "female infertility"
    }
  ]
}