{
  "id": 15699,
  "label": "craniosynostosis 6",
  "model": {
    "label": "Mondo Disease Ontology (MONDO)",
    "source": 0
  },
  "type_id": 0,
  "reference_id": "MONDO:0014705",
  "properties": {
    "xrefs": [
      "DOID:0061008",
      "GARD:0018048",
      "MEDGEN:904675",
      "OMIM:616602",
      "Orphanet:672985",
      "UMLS:C4225269"
    ],
    "synonyms": [
      "ZIC1 craniosynostosis",
      "craniosynostosis 6",
      "craniosynostosis caused by mutation in ZIC1",
      "craniosynostosis type 6",
      "CRS6"
    ],
    "categories": [
      {
        "ref": "MONDO:0002081",
        "name": "musculoskeletal system disorder"
      }
    ],
    "definition": "Any craniosynostosis in which the cause of the disease is a mutation in the ZIC1 gene."
  },
  "isLeaf": true,
  "isRoot": false,
  "child_count": 0,
  "parents": [
    {
      "id": 18891,
      "label": "isolated oxycephaly",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        16200
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "GARD:0025134",
          "MEDGEN:1726910",
          "Orphanet:63440",
          "SCTID:48069004",
          "UMLS:C5399823"
        ],
        "synonyms": [
          "acrocephaly",
          "hypsicephaly",
          "hypsocephaly",
          "pyrgocephaly",
          "turricephaly"
        ],
        "categories": [
          {
            "ref": "MONDO:0002081",
            "name": "musculoskeletal system disorder"
          }
        ],
        "definition": "Isolated oxycephaly is a late-appearing form of nonsyndromic craniosynostosis characterized by premature fusion of both the coronal and sagittal sutures, and, in some cases, of the lambdoid sutures. Compensatory growth in the region of the anterior fontanel results in a pointed or cone-shaped skull."
      },
      "child_count": 2,
      "reference_id": "MONDO:0018971"
    }
  ],
  "children": [],
  "roots": [
    {
      "id": 18891,
      "label": "isolated oxycephaly"
    }
  ]
}