{
  "id": 15861,
  "label": "Duane retraction syndrome 3 with or without deafness",
  "model": {
    "label": "Mondo Disease Ontology (MONDO)",
    "source": 0
  },
  "type_id": 0,
  "reference_id": "MONDO:0014880",
  "properties": {
    "xrefs": [
      "DOID:0061029",
      "GARD:0010691",
      "MEDGEN:934719",
      "OMIM:617041",
      "UMLS:C4310752"
    ],
    "synonyms": [
      "DURS3",
      "Duane retraction syndrome 3 with or without deafness",
      "Duane retraction syndrome caused by mutation in MAFB",
      "MAFB Duane retraction syndrome",
      "Duane retraction syndrome 3",
      "Duane syndrome type 3"
    ],
    "categories": [
      {
        "ref": "MONDO:0002254",
        "name": "syndromic disease"
      },
      {
        "ref": "MONDO:0005071",
        "name": "nervous system disorder"
      },
      {
        "ref": "MONDO:0024458",
        "name": "disorder of visual system"
      }
    ],
    "definition": "Duane syndrome type 3 is a disorder of eye movement.The affected eye, or eyes, has limited ability to move both inward toward the nose and outward toward the ears. The eye opening narrows and the eyeball pulls in when looking inward toward the nose. About 15 percent of all cases of Duane syndrome are type 3. Most cases occur without other signs and symptoms.In most people with Duane syndrome type 3, the cause is unknown; but it can sometimes be caused by mutations in the CHN1 gene and inherited in an autosomal dominant fashion."
  },
  "isLeaf": true,
  "isRoot": false,
  "child_count": 0,
  "parents": [
    {
      "id": 8860,
      "label": "Duane retraction syndrome",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        4370,
        16052,
        24270
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:12557",
          "GARD:0006288",
          "ICD10CM:H50.81",
          "ICD9:378.71",
          "MEDGEN:4413",
          "MESH:D004370",
          "MedDRA:10013799",
          "NCIT:C84678",
          "NORD:1062",
          "OMIMPS:126800",
          "Orphanet:233",
          "SCTID:60318001",
          "UMLS:C0013261"
        ],
        "synonyms": [
          "DRS",
          "DURS",
          "Duane retraction syndrome",
          "Duane syndrome",
          "Duane's syndrome",
          "Stilling-Turk-Duane syndrome",
          "Duane anomaly",
          "retraction syndrome"
        ],
        "categories": [
          {
            "ref": "MONDO:0002254",
            "name": "syndromic disease"
          },
          {
            "ref": "MONDO:0005071",
            "name": "nervous system disorder"
          },
          {
            "ref": "MONDO:0024458",
            "name": "disorder of visual system"
          }
        ],
        "definition": "Duane retraction syndrome (DRS) is a congenital form of strabismus characterized by horizontal eye movement limitation, globe retraction and palpebral fissure narrowing in attempted adduction. It is caused by a failure of development of the abducens nerve and can lead to amblyopia."
      },
      "child_count": 12,
      "reference_id": "MONDO:0007473"
    }
  ],
  "children": [],
  "roots": [
    {
      "id": 8860,
      "label": "Duane retraction syndrome"
    }
  ]
}