{
  "id": 16045,
  "label": "middle ear neuroendocrine tumor",
  "model": {
    "label": "Mondo Disease Ontology (MONDO)",
    "source": 0
  },
  "type_id": 0,
  "reference_id": "MONDO:0015071",
  "properties": {
    "xrefs": [
      "GARD:0019759",
      "MEDGEN:931137",
      "Orphanet:100084",
      "SCTID:717918002",
      "UMLS:C4305468",
      "icd11.foundation:1437498002"
    ],
    "synonyms": [
      "middle ear NET",
      "middle ear neuroendocrine neoplasm",
      "middle ear neuroendocrine tumor",
      "middle ear neuroendocrine tumor, well differentiated, low or intermediate grade",
      "neuroendocrine neoplasm of middle ear",
      "neuroendocrine tumor of middle ear",
      "neuroendocrine tumour of middle ear"
    ],
    "categories": [
      {
        "ref": "MONDO:0002409",
        "name": "auditory system disorder"
      },
      {
        "ref": "MONDO:0005151",
        "name": "endocrine system disorder"
      },
      {
        "ref": "MONDO:0024623",
        "name": "otorhinolaryngologic disease"
      }
    ],
    "definition": "A neuroendocrine neoplasm that involves the middle ear."
  },
  "isLeaf": false,
  "isRoot": false,
  "child_count": 1,
  "parents": [
    {
      "id": 19314,
      "label": "neuroendocrine neoplasm",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        4223
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:169",
          "EFO:1001901",
          "GARD:0009316",
          "ICD9:209",
          "ICD9:209-209",
          "ICD9:239.7",
          "MEDGEN:64652",
          "MESH:D018358",
          "NCIT:C188218",
          "NCIT:C3809",
          "Orphanet:877",
          "SCTID:255046005",
          "UMLS:C0206754"
        ],
        "synonyms": [
          "APUDoma",
          "neuroendocrine neoplasm",
          "neuroendocrine tumor",
          "neuroendocrine tumour"
        ],
        "categories": [
          {
            "ref": "MONDO:0005151",
            "name": "endocrine system disorder"
          }
        ],
        "definition": "Endocrine tumors, also referred to as neuroendocrine tumors (NETs), are defined by a common phenotype which is characterized by the expression of general markers (neuron specific enolase, chromogranin, synaptophysin) and hormone secretion products. These tumors may be localized in any part of the body and are generally discovered in non-specific situations, i.e. not immediately suggestive of NETs (tests for inherited predisposition to tumors or for a clinical syndrome caused by abnormal hormone secretion)."
      },
      "child_count": 14,
      "reference_id": "MONDO:0019496"
    },
    {
      "id": 20527,
      "label": "neoplasm of middle ear",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        5217,
        20443
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "ICD9:239.89",
          "MEDGEN:87509",
          "NCIT:C4412",
          "SCTID:127006003",
          "UMLS:C0345617"
        ],
        "synonyms": [
          "middle Ear neoplasm",
          "middle Ear tumor",
          "middle Ear tumour",
          "middle ear neoplasm",
          "middle ear neoplasm (disease)",
          "middle ear tumor",
          "middle ear tumour",
          "neoplasm of middle ear",
          "neoplasm of the middle Ear",
          "tumor of middle Ear",
          "tumor of middle ear",
          "tumor of the middle Ear",
          "tumour of middle Ear",
          "tumour of middle ear",
          "tumour of the middle Ear"
        ],
        "categories": [
          {
            "ref": "MONDO:0002409",
            "name": "auditory system disorder"
          },
          {
            "ref": "MONDO:0024623",
            "name": "otorhinolaryngologic disease"
          }
        ],
        "definition": "A neoplasm (disease) that involves the middle ear."
      },
      "child_count": 8,
      "reference_id": "MONDO:0021366"
    }
  ],
  "children": [
    {
      "id": 21266,
      "label": "tympanic paraganglioma",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        7791,
        16045,
        18718,
        22991
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "GARD:0008658",
          "GTR:AN0102047",
          "GTR:AN0102048",
          "MEDGEN:105375",
          "MESH:D043604",
          "NCIT:C8428",
          "SCTID:253031000",
          "UMLS:C0474820"
        ],
        "synonyms": [
          "tympanic paraganglioma",
          "Glomus Tympanicum Tumor",
          "Glomus Tympanicum Tumors",
          "Glomus Tympanicum Tumour",
          "Glomus Tympanicum Tumours",
          "Glomus tympanicum paraganglioma",
          "Glomus tympanicum tumor",
          "Glomus tympanicum tumour",
          "Tumor, Glomus Tympanicum",
          "Tumors, Glomus Tympanicum",
          "Tympanic Paraganglioma",
          "Tympanic paraganglioma"
        ],
        "categories": [
          {
            "ref": "MONDO:0002409",
            "name": "auditory system disorder"
          },
          {
            "ref": "MONDO:0005071",
            "name": "nervous system disorder"
          },
          {
            "ref": "MONDO:0005151",
            "name": "endocrine system disorder"
          },
          {
            "ref": "MONDO:0024623",
            "name": "otorhinolaryngologic disease"
          }
        ],
        "definition": "A benign or malignant middle ear paraganglioma arising from paraganglia around the tympanum. Signs and symptoms include a mass behind the tympanum, tinnitus, and conductive hearing loss."
      },
      "child_count": 0,
      "reference_id": "MONDO:0023682"
    }
  ],
  "roots": [
    {
      "id": 19314,
      "label": "neuroendocrine neoplasm"
    },
    {
      "id": 20527,
      "label": "neoplasm of middle ear"
    }
  ]
}