{
  "id": 16047,
  "label": "gallbladder neuroendocrine tumor, grade 1/2",
  "model": {
    "label": "Mondo Disease Ontology (MONDO)",
    "source": 0
  },
  "type_id": 0,
  "reference_id": "MONDO:0015073",
  "properties": {
    "xrefs": [
      "GARD:0019761",
      "MEDGEN:474749",
      "NCIT:C96918",
      "Orphanet:100086",
      "UMLS:C3273116"
    ],
    "synonyms": [
      "gallbladder NET",
      "gallbladder neuroendocrine tumor",
      "gallbladder neuroendocrine tumour",
      "gallbladder well differentiated endocrine tumor",
      "gallbladder well differentiated endocrine tumor/carcinoma",
      "gallbladder well differentiated endocrine tumour"
    ],
    "categories": [
      {
        "ref": "MONDO:0004335",
        "name": "digestive system disorder"
      },
      {
        "ref": "MONDO:0005151",
        "name": "endocrine system disorder"
      }
    ],
    "definition": "A well differentiated, low or intermediate grade tumor with neuroendocrine differentiation that arises from the gallbladder."
  },
  "isLeaf": true,
  "isRoot": false,
  "child_count": 0,
  "parents": [
    {
      "id": 2885,
      "label": "digestive system neuroendocrine tumor, grade 1/2",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        21456
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:0050626",
          "GARD:0022761",
          "MEDGEN:443945",
          "NCIT:C95404",
          "ONCOTREE:GINET",
          "UMLS:C2930967"
        ],
        "synonyms": [
          "alimentary part of gastrointestinal system neuroendocrine tumor",
          "alimentary part of gastrointestinal system neuroendocrine tumour",
          "digestive system NET",
          "digestive system neuroendocrine tumor",
          "digestive system neuroendocrine tumour",
          "digestive system well differentiated neuroendocrine tumor",
          "digestive system well differentiated neuroendocrine tumour",
          "gastroenteropancreatic NET",
          "gastroenteropancreatic neuroendocrine tumor",
          "gastroenteropancreatic neuroendocrine tumour",
          "gastrointestinal NET",
          "gastrointestinal neuroendocrine tumor",
          "gastrointestinal neuroendocrine tumors",
          "gastrointestinal neuroendocrine tumour",
          "gastrointestinal neuroendocrine tumours",
          "gastrointestinal system neuroendocrine tumor",
          "gastrointestinal system neuroendocrine tumour",
          "malignant gastrointestinal neuroendocrine tumor",
          "malignant gastrointestinal neuroendocrine tumour",
          "GINET"
        ],
        "categories": [
          {
            "ref": "MONDO:0004335",
            "name": "digestive system disorder"
          },
          {
            "ref": "MONDO:0005151",
            "name": "endocrine system disorder"
          }
        ],
        "definition": "A well-differentiated neuroendocrine tumor arising from the digestive system. It is characterized by the presence of cells with features similar to those of the normal endocrine cells of the digestive system. The neoplastic cells express immunohistochemical evidence of neuroendocrine differentiation and hormones. There is mild to moderate nuclear atypia and less than 20 mitoses per 10 HPF. It includes well-differentiated endocrine tumors or carcinoid tumors and well-differentiated endocrine carcinomas."
      },
      "child_count": 10,
      "reference_id": "MONDO:0000386"
    },
    {
      "id": 20541,
      "label": "extrahepatic bile duct neoplasm",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        20714
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "MEDGEN:91056",
          "NCIT:C4441",
          "SCTID:126855001",
          "UMLS:C0345913"
        ],
        "synonyms": [
          "extrahepatic bile duct neoplasm",
          "extrahepatic bile duct neoplasm (disease)",
          "extrahepatic bile duct tumor",
          "extrahepatic bile duct tumour",
          "neoplasm of extrahepatic bile duct",
          "neoplasm of the extrahepatic bile duct",
          "tumor of extrahepatic bile duct",
          "tumor of the extrahepatic bile duct",
          "tumour of extrahepatic bile duct",
          "tumour of the extrahepatic bile duct"
        ],
        "categories": [
          {
            "ref": "MONDO:0004335",
            "name": "digestive system disorder"
          },
          {
            "ref": "MONDO:0005151",
            "name": "endocrine system disorder"
          }
        ],
        "definition": "A benign or malignant neoplasm that affects the extrahepatic bile ducts. Representative examples include adenoma and adenocarcinoma."
      },
      "child_count": 7,
      "reference_id": "MONDO:0021385"
    },
    {
      "id": 21455,
      "label": "gallbladder neuroendocrine neoplasm",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        20460,
        21456
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "GARD:0025405",
          "MEDGEN:474748",
          "NCIT:C96917",
          "UMLS:C3273115"
        ],
        "synonyms": [
          "gall bladder NET",
          "gall bladder neuroendocrine neoplasm",
          "gall bladder neuroendocrine tumor",
          "gall bladder neuroendocrine tumor, well differentiated, low or intermediate grade",
          "gall bladder neuroendocrine tumour",
          "gallbladder neuroendocrine neoplasm",
          "neuroendocrine neoplasm of gall bladder"
        ],
        "categories": [
          {
            "ref": "MONDO:0004335",
            "name": "digestive system disorder"
          },
          {
            "ref": "MONDO:0005151",
            "name": "endocrine system disorder"
          }
        ],
        "definition": "A neoplasm with neuroendocrine differentiation that arises from the gallbladder. It includes well differentiated neuroendocrine tumors (low and intermediate grade) and poorly differentiated neuroendocrine carcinomas (high grade)."
      },
      "child_count": 4,
      "reference_id": "MONDO:0024502"
    }
  ],
  "children": [],
  "roots": [
    {
      "id": 2885,
      "label": "digestive system neuroendocrine tumor, grade 1/2"
    },
    {
      "id": 20541,
      "label": "extrahepatic bile duct neoplasm"
    },
    {
      "id": 21455,
      "label": "gallbladder neuroendocrine neoplasm"
    }
  ]
}