{
  "id": 16052,
  "label": "nuclear oculomotor paralysis",
  "model": {
    "label": "Mondo Disease Ontology (MONDO)",
    "source": 0
  },
  "type_id": 0,
  "reference_id": "MONDO:0015083",
  "properties": {
    "xrefs": [
      "Orphanet:100932"
    ],
    "categories": [
      {
        "ref": "MONDO:0005071",
        "name": "nervous system disorder"
      },
      {
        "ref": "MONDO:0024458",
        "name": "disorder of visual system"
      }
    ]
  },
  "isLeaf": false,
  "isRoot": false,
  "child_count": 6,
  "parents": [
    {
      "id": 3541,
      "label": "oculomotor nerve paralysis",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        4811,
        5451,
        21415
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:11550",
          "GARD:0019544",
          "MEDGEN:14459",
          "NCIT:C27597",
          "Orphanet:98685",
          "SCTID:388980004",
          "UMLS:C0028866"
        ],
        "synonyms": [
          "IIIrd nerve paralysis",
          "cranial nerve palsy of oculomotor nerve",
          "oculomotor nerve cranial nerve palsy",
          "oculomotor nerve paralysis",
          "oculomotor palsy"
        ],
        "categories": [
          {
            "ref": "MONDO:0005071",
            "name": "nervous system disorder"
          },
          {
            "ref": "MONDO:0024458",
            "name": "disorder of visual system"
          }
        ],
        "definition": "Paralysis of the oculomotor nerve."
      },
      "child_count": 15,
      "reference_id": "MONDO:0001309"
    }
  ],
  "children": [
    {
      "id": 8860,
      "label": "Duane retraction syndrome",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        4370,
        16052,
        24270
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:12557",
          "GARD:0006288",
          "ICD10CM:H50.81",
          "ICD9:378.71",
          "MEDGEN:4413",
          "MESH:D004370",
          "MedDRA:10013799",
          "NCIT:C84678",
          "NORD:1062",
          "OMIMPS:126800",
          "Orphanet:233",
          "SCTID:60318001",
          "UMLS:C0013261"
        ],
        "synonyms": [
          "DRS",
          "DURS",
          "Duane retraction syndrome",
          "Duane syndrome",
          "Duane's syndrome",
          "Stilling-Turk-Duane syndrome",
          "Duane anomaly",
          "retraction syndrome"
        ],
        "categories": [
          {
            "ref": "MONDO:0002254",
            "name": "syndromic disease"
          },
          {
            "ref": "MONDO:0005071",
            "name": "nervous system disorder"
          },
          {
            "ref": "MONDO:0024458",
            "name": "disorder of visual system"
          }
        ],
        "definition": "Duane retraction syndrome (DRS) is a congenital form of strabismus characterized by horizontal eye movement limitation, globe retraction and palpebral fissure narrowing in attempted adduction. It is caused by a failure of development of the abducens nerve and can lead to amblyopia."
      },
      "child_count": 12,
      "reference_id": "MONDO:0007473"
    },
    {
      "id": 8991,
      "label": "familial congenital palsy of trochlear nerve",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        4427,
        16052,
        24270,
        24774
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "GARD:0010355",
          "MEDGEN:338185",
          "MESH:C565007",
          "OMIM:136480",
          "Orphanet:91498",
          "UMLS:C1850996"
        ],
        "synonyms": [
          "hereditary fourth cranial nerve palsy",
          "fourth cranial nerve palsy, familial congenital",
          "strabismus from Superior oblique palsy",
          "superior oblique oculomotor palsy, familial congenital",
          "trochlear nerve palsy, familial congenital"
        ],
        "categories": [
          {
            "ref": "MONDO:0005071",
            "name": "nervous system disorder"
          },
          {
            "ref": "MONDO:0024458",
            "name": "disorder of visual system"
          }
        ],
        "definition": "An instance of fourth cranial nerve palsy that is caused by an inherited modification of the individual's genome."
      },
      "child_count": 0,
      "reference_id": "MONDO:0007626"
    },
    {
      "id": 9332,
      "label": "Mobius syndrome",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        4235,
        4370,
        4427,
        16052,
        16088
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:13501",
          "GARD:0008549",
          "ICD9:759.89",
          "MEDGEN:66357",
          "MESH:D020331",
          "MedDRA:10027789",
          "MedDRA:10030069",
          "NANDO:1200559",
          "NANDO:2200980",
          "NCIT:C84893",
          "NORD:1453",
          "OMIM:157900",
          "Orphanet:570",
          "SCTID:89444000",
          "UMLS:C0221060"
        ],
        "synonyms": [
          "MBS",
          "Mobius syndrome",
          "Moebius Syndrome",
          "Moebius sequence",
          "Moebius syndrome",
          "Moebius syndrome, Isolated cases",
          "Möbius syndrome",
          "congenital facial diplegia",
          "oromandibular-limb hypogenesis spectrum",
          "absence or underdevelopment of the 6th and 7th cranial nerves",
          "congenital facial diplegia syndrome",
          "congenital oculofacial paralysis"
        ],
        "categories": [
          {
            "ref": "MONDO:0002254",
            "name": "syndromic disease"
          },
          {
            "ref": "MONDO:0005071",
            "name": "nervous system disorder"
          },
          {
            "ref": "MONDO:0024458",
            "name": "disorder of visual system"
          }
        ],
        "definition": "Moebius syndrome is a very rare congenital cranial dysinnervation disorder characterized by complete or incomplete facial paralysis in association with bilateral palsy of the abducens nerve causing impairment of ocular abduction. The syndrome also includes various other congenital anomalies."
      },
      "child_count": 5,
      "reference_id": "MONDO:0008006"
    },
    {
      "id": 18601,
      "label": "congenital oculomotor nerve palsy",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        4427,
        16052
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "GARD:0021836",
          "MEDGEN:1804232",
          "Orphanet:440221",
          "UMLS:C5680054",
          "icd11.foundation:2135160463"
        ],
        "synonyms": [
          "congenital CNIII lesion",
          "congenital third cranial nerve palsy"
        ],
        "categories": [
          {
            "ref": "MONDO:0005071",
            "name": "nervous system disorder"
          },
          {
            "ref": "MONDO:0024458",
            "name": "disorder of visual system"
          }
        ]
      },
      "child_count": 0,
      "reference_id": "MONDO:0018599"
    },
    {
      "id": 18602,
      "label": "congenital abducens nerve palsy",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        4427,
        16052
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "GARD:0021837",
          "MEDGEN:724505",
          "Orphanet:440233",
          "UMLS:C1302994"
        ],
        "synonyms": [
          "benign congenital sixth cranial nerve palsy",
          "congenital CNVI palsy"
        ],
        "categories": [
          {
            "ref": "MONDO:0005071",
            "name": "nervous system disorder"
          },
          {
            "ref": "MONDO:0024458",
            "name": "disorder of visual system"
          }
        ]
      },
      "child_count": 0,
      "reference_id": "MONDO:0018600"
    },
    {
      "id": 18902,
      "label": "Tolosa-Hunt syndrome",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        3785,
        4370,
        16052
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:1278",
          "GARD:0007777",
          "MEDGEN:21197",
          "MESH:D020333",
          "MedDRA:10051526",
          "NCIT:C85193",
          "NORD:1774",
          "Orphanet:64686",
          "SCTID:95794005",
          "UMLS:C0040381",
          "icd11.foundation:969826782"
        ],
        "synonyms": [
          "Tolosa Hunt Syndrome",
          "Tolosa Hunt syndrome",
          "Tolosa-Hunt syndrome",
          "painful ophthalmoplegia",
          "THS",
          "nonspecific inflammation of the cavernous sinus or superior orbital fissure"
        ],
        "categories": [
          {
            "ref": "MONDO:0002254",
            "name": "syndromic disease"
          },
          {
            "ref": "MONDO:0005071",
            "name": "nervous system disorder"
          },
          {
            "ref": "MONDO:0024458",
            "name": "disorder of visual system"
          }
        ],
        "definition": "Tolosa-Hunt syndrome is an ophthalmoplegic syndrome, affecting all age groups, characterized by acute attacks (lasting a few days to a few weeks) of periorbital pain, ipsilateral ocular motor nerve palsies, ptosis, disordered eye movements and blurred vision usually caused by a non-specific inflammatory process in the cavernous sinus and superior orbital fissure. It has an unpredictable course with spontaneous remission occurring in some and recurrence of attacks in others."
      },
      "child_count": 0,
      "reference_id": "MONDO:0018983"
    }
  ],
  "roots": [
    {
      "id": 3541,
      "label": "oculomotor nerve paralysis"
    }
  ]
}