{
  "id": 16114,
  "label": "coronary artery congenital malformation",
  "model": {
    "label": "Mondo Disease Ontology (MONDO)",
    "source": 0
  },
  "type_id": 0,
  "reference_id": "MONDO:0015203",
  "properties": {
    "xrefs": [
      "DOID:11843",
      "GARD:0001534",
      "ICD9:746.85",
      "MEDGEN:1612789",
      "MedDRA:10061060",
      "Orphanet:1081",
      "SCTID:28574005",
      "UMLS:C4531298",
      "icd11.foundation:902783759"
    ],
    "synonyms": [
      "congenital anomaly of coronary artery",
      "congenital coronary artery anomaly",
      "coronary artery abnormality [ambiguous]",
      "coronary artery anomaly",
      "coronary artery anomaly, congenital"
    ],
    "categories": [
      {
        "ref": "MONDO:0004995",
        "name": "cardiovascular disorder"
      }
    ],
    "definition": "A coronary artery disorder characterized by abnormal origin, course, or structure of one or more coronary arteries present at birth."
  },
  "isLeaf": false,
  "isRoot": false,
  "child_count": 9,
  "parents": [
    {
      "id": 6748,
      "label": "coronary artery disorder",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        2933,
        6967
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:3393",
          "EFO:0001645",
          "ICD9:410-414",
          "ICD9:414.0",
          "ICD9:414.9",
          "MEDGEN:365486",
          "MESH:D003324",
          "NCIT:C26732",
          "SCTID:414024009",
          "UMLS:C1956346",
          "icd11.foundation:1059873720"
        ],
        "synonyms": [
          "CAD",
          "CHD (coronary heart disease)",
          "coronary artery disease",
          "coronary artery disease or disorder",
          "coronary disease",
          "coronary heart disease",
          "disease of coronary artery",
          "disease or disorder of coronary artery",
          "disorder of coronary artery",
          "coronary arteriosclerosis"
        ],
        "categories": [
          {
            "ref": "MONDO:0004995",
            "name": "cardiovascular disorder"
          }
        ],
        "definition": "Narrowing of the coronary arteries due to fatty deposits inside the arterial walls. The diagnostic criteria may include documented history of any of the following: documented coronary artery stenosis greater than or equal to 50% (by cardiac catheterization or other modality of direct imaging of the coronary arteries); previous coronary artery bypass surgery (CABG); previous percutaneous coronary intervention (PCI); previous myocardial infarction. (ACC)"
      },
      "child_count": 24,
      "reference_id": "MONDO:0005010"
    },
    {
      "id": 7116,
      "label": "congenital heart disease",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        6967,
        21294
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:1682",
          "EFO:0005207",
          "ICD9:746.84",
          "ICD9:746.89",
          "ICD9:746.9",
          "MEDGEN:57501",
          "MESH:D006330",
          "NCIT:C95834",
          "SCTID:13213009",
          "UMLS:C0152021",
          "icd11.foundation:2004408087"
        ],
        "synonyms": [
          "heart malformation",
          "congenital anomaly of heart",
          "congenital heart defect",
          "congenital heart defects",
          "Abnormality, heart",
          "abnormalities, heart",
          "defect, congenital heart",
          "defects, congenital heart",
          "heart abnormalities",
          "heart abnormality",
          "heart defect, congenital",
          "heart, malformation Of"
        ],
        "categories": [
          {
            "ref": "MONDO:0004995",
            "name": "cardiovascular disorder"
          }
        ],
        "definition": "A heart disease that is present at birth. Representative examples include atrial septal defect, ventricular septal defect, tetralogy of Fallot, and patent foramen ovale."
      },
      "child_count": 46,
      "reference_id": "MONDO:0005453"
    },
    {
      "id": 19327,
      "label": "congenital heart malformation",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        21294
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "EFO:0005269",
          "MEDGEN:1680993",
          "Orphanet:88991",
          "UMLS:C3649636"
        ],
        "synonyms": [
          "congenital heart malformation",
          "disorder of heart development",
          "heart development disease",
          "congenital non-syndromic heart malformation",
          "rare congenital non-syndromic heart malformation"
        ],
        "categories": [
          {
            "ref": "MONDO:0004995",
            "name": "cardiovascular disorder"
          }
        ],
        "definition": "A disease that has its basis in the disruption of heart development."
      },
      "child_count": 26,
      "reference_id": "MONDO:0019512"
    }
  ],
  "children": [
    {
      "id": 3139,
      "label": "anomalous left coronary artery from the pulmonary artery",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        16114
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:0060562",
          "GARD:0027562",
          "MEDGEN:760471",
          "MESH:D063748",
          "NANDO:2200242",
          "UMLS:C1735886"
        ],
        "synonyms": [
          "ALCAPA disorder",
          "BWGS",
          "Bland-White-Garland syndrome"
        ],
        "categories": [
          {
            "ref": "MONDO:0004995",
            "name": "cardiovascular disorder"
          }
        ],
        "definition": "A congenital coronary vessel anomaly in which the left main coronary artery originates from the pulmonary artery instead of from aorta. The congenital heart defect typically results in coronary artery fistula; left-sided heart failure and mitral valve insufficiency during the first months of life."
      },
      "child_count": 0,
      "reference_id": "MONDO:0000811"
    },
    {
      "id": 16710,
      "label": "coronary arterial fistulas",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        16114
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "GARD:0001533",
          "MEDGEN:488822",
          "MedDRA:10069441",
          "NANDO:2200296",
          "Orphanet:2041",
          "UMLS:C0265898"
        ],
        "synonyms": [
          "Coronaro-cardiac fistula",
          "coronary arterial malformations"
        ],
        "categories": [
          {
            "ref": "MONDO:0004995",
            "name": "cardiovascular disorder"
          }
        ],
        "definition": "A congenital disorder characterized by an abnormal connection between one or more of the coronary arteries and a cardiac chamber or great vessel."
      },
      "child_count": 0,
      "reference_id": "MONDO:0016081"
    },
    {
      "id": 19563,
      "label": "congenital coronary artery aneurysm",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        16114
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "GARD:0019273",
          "MEDGEN:573848",
          "Orphanet:95491",
          "SCTID:204378009",
          "UMLS:C0340627",
          "icd11.foundation:1376805686"
        ],
        "synonyms": [
          "congenital coronary aneurysm"
        ],
        "categories": [
          {
            "ref": "MONDO:0004995",
            "name": "cardiovascular disorder"
          }
        ],
        "definition": "Congenital coronary artery aneurysm is a rare congenital coronary artery malformation defined as a more than 1.5 fold the normal size dilatation of a coronary artery segment with no identified underlying inflammatory or connective tissue disease. It may be asymptomatic or may present with angina pectoris, myocardial infarction, sudden cardiac death, fistula formation, pericardial tamponade, compression of surrounding structures, or congestive heart failure."
      },
      "child_count": 0,
      "reference_id": "MONDO:0019825"
    },
    {
      "id": 19880,
      "label": "coronary artery intramyocardial course",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        16114
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "GARD:0025162",
          "MEDGEN:182684",
          "Orphanet:99085",
          "UMLS:C0948355"
        ],
        "categories": [
          {
            "ref": "MONDO:0004995",
            "name": "cardiovascular disorder"
          }
        ]
      },
      "child_count": 0,
      "reference_id": "MONDO:0020421"
    },
    {
      "id": 19881,
      "label": "aortopulmonary coronary arterial course",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        16114
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "GARD:0025163",
          "MEDGEN:1668023",
          "Orphanet:99086",
          "UMLS:C4757971"
        ],
        "categories": [
          {
            "ref": "MONDO:0004995",
            "name": "cardiovascular disorder"
          }
        ],
        "definition": "Aortopulmonary coronary arterial course is a rare coronary artery congenital malformation characterized by anomalous origin of the coronary artery from the contralateral sinus of Valsalva with course between the aorta and the pulmonary artery. The anomaly is associated with increased risk of sudden cardiac death, especially during exercise."
      },
      "child_count": 0,
      "reference_id": "MONDO:0020422"
    },
    {
      "id": 19882,
      "label": "stenosis or atrophy of the coronary ostium",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        16114
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "GARD:0019643",
          "MEDGEN:1842382",
          "Orphanet:99087",
          "UMLS:C5575847"
        ],
        "synonyms": [
          "coronary ostial stenosis or atresia",
          "stenosis or atresia of the coronary ostium"
        ],
        "categories": [
          {
            "ref": "MONDO:0004995",
            "name": "cardiovascular disorder"
          }
        ]
      },
      "child_count": 0,
      "reference_id": "MONDO:0020423"
    },
    {
      "id": 19883,
      "label": "intramural coronary arterial course",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        16114
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "GARD:0025164",
          "MEDGEN:576769",
          "Orphanet:99088",
          "UMLS:C0345123"
        ],
        "categories": [
          {
            "ref": "MONDO:0004995",
            "name": "cardiovascular disorder"
          }
        ],
        "definition": "Intramural coronary arterial course is a rare coronary artery congenital malformation disorder characterized by an atypical course of a coronary artery (usually proximal left anterior descending artery) in which, for a variable length, the artery runs intramyocardally. Depending on the artery and length of segment involved, patients may be asymptomatic or may present variable manifestations ranging from atypical angina to sudden death."
      },
      "child_count": 0,
      "reference_id": "MONDO:0020424"
    },
    {
      "id": 19884,
      "label": "abnormal number of coronary ostia",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        16114
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "GARD:0019644",
          "MEDGEN:1676211",
          "Orphanet:99089",
          "UMLS:C5191081"
        ],
        "categories": [
          {
            "ref": "MONDO:0004995",
            "name": "cardiovascular disorder"
          }
        ]
      },
      "child_count": 0,
      "reference_id": "MONDO:0020425"
    },
    {
      "id": 19885,
      "label": "malposition of the coronary ostium",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        16114
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "GARD:0019645",
          "MEDGEN:759190",
          "Orphanet:99090",
          "UMLS:C3532077"
        ],
        "categories": [
          {
            "ref": "MONDO:0004995",
            "name": "cardiovascular disorder"
          }
        ],
        "definition": "Malposition of the coronary ostium is a rare coronary artery congenital malformation characterized by displacement of one of the coronary arteries, originating closer to the aortic root or to the commissural area. The anomaly is considered to be asymptomatic, however, it may impose surgical difficulties during aortic root surgery."
      },
      "child_count": 0,
      "reference_id": "MONDO:0020426"
    }
  ],
  "roots": [
    {
      "id": 6748,
      "label": "coronary artery disorder"
    },
    {
      "id": 7116,
      "label": "congenital heart disease"
    },
    {
      "id": 19327,
      "label": "congenital heart malformation"
    }
  ]
}