{
  "id": 16132,
  "label": "allergic bronchopulmonary aspergillosis",
  "model": {
    "label": "Mondo Disease Ontology (MONDO)",
    "source": 0
  },
  "type_id": 0,
  "reference_id": "MONDO:0015243",
  "properties": {
    "xrefs": [
      "DOID:13166",
      "EFO:0007140",
      "GARD:0000602",
      "ICD10CM:B44.81",
      "ICD9:518.6",
      "MEDGEN:479932",
      "MESH:D001229",
      "MedDRA:10006474",
      "NCIT:C84547",
      "OMIM:103920",
      "Orphanet:1164",
      "SCTID:37981002",
      "UMLS:C3278302",
      "icd11.foundation:1591607082"
    ],
    "synonyms": [
      "ABPA",
      "Hinson-Pepys disease",
      "allergic aspergillosis",
      "allergic bronchopulmonary aspergillosis, familial",
      "allergic bronchopulmonary mycosis",
      "aspergillosis, allergic bronchopulmonary"
    ],
    "categories": [
      {
        "ref": "MONDO:0005046",
        "name": "immune system disorder"
      },
      {
        "ref": "MONDO:0005087",
        "name": "respiratory system disorder"
      }
    ],
    "definition": "Allergic bronchopulmonary aspergillosis (ABPA) is a rare immunologic pulmonary disorder caused by hypersensitivity to Aspergillus fumigatus, clinically manifesting with poorly controlled asthma and recurrent pulmonary infiltrates."
  },
  "isLeaf": false,
  "isRoot": false,
  "child_count": 1,
  "parents": [
    {
      "id": 3133,
      "label": "allergic respiratory disease",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        6815,
        6969
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:0060496",
          "MEDGEN:734246",
          "UMLS:C1504369"
        ],
        "synonyms": [
          "allergic form of respiratory system disease",
          "allergic respiratory system disease"
        ],
        "categories": [
          {
            "ref": "MONDO:0005046",
            "name": "immune system disorder"
          },
          {
            "ref": "MONDO:0005087",
            "name": "respiratory system disorder"
          }
        ],
        "definition": "A respiratory system disease with a basis in a pathological type I hypersensitivity reaction."
      },
      "child_count": 8,
      "reference_id": "MONDO:0000771"
    },
    {
      "id": 7292,
      "label": "aspergillosis",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        4420
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "CSP:1988-4002",
          "DOID:13564",
          "EFO:0007157",
          "GARD:0005856",
          "ICD10CM:B44",
          "ICD10WHO:B44",
          "ICD9:117.3",
          "MEDGEN:13939",
          "MESH:D001228",
          "MedDRA:10003488",
          "NCIT:C2886",
          "NORD:814",
          "Orphanet:1163",
          "SCTID:65553006",
          "UMLS:C0004030",
          "icd11.foundation:1913468488"
        ],
        "definition": "Aspergillosis is an infection, growth, or allergic response caused by the Aspergillus fungus. There are several different kinds of aspergillosis. One kind is allergic bronchopulmonary aspergillosis (also called ABPA), a condition where the fungus causes allergic respiratory symptoms similar to asthma, such as wheezing and coughing, but does not actually invade and destroy tissue. Another kind of aspergillosis is invasive aspergillosis. This infection usually affects people with weakened immune systems due to cancer, AIDS, leukemia, organ transplantation, chemotherapy, or other conditions or events that reduce the number of normal white blood cells. In this condition, the fungus invades and damages tissues in the body. Invasive aspergillosis most commonly affects the lungs, but can also cause infection in many other organs and can spread throughout the body (commonly affecting the kidneys and brain). Aspergilloma, a growth (fungus ball) that develops in an area of previous lung disease such as tuberculosis or lung abscess, is a third kind of aspergillosis. This type of aspergillosis is composed of a tangled mass of fungus fibers, blood clots, and white blood cells. The fungus ball gradually enlarges, destroying lung tissue in the process, but usually does not spread to other areas."
      },
      "child_count": 4,
      "reference_id": "MONDO:0005657"
    }
  ],
  "children": [
    {
      "id": 4381,
      "label": "malt worker's lung",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        2808,
        16132,
        18069,
        20956
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:2314",
          "GARD:0023103",
          "ICD9:495.4",
          "MEDGEN:510125",
          "SCTID:25897000",
          "UMLS:C0155888"
        ],
        "synonyms": [
          "Aspergillus caused extrinsic allergic alveolitis",
          "Aspergillus extrinsic allergic alveolitis",
          "Malt workers' lung",
          "malt workers lung",
          "alveolitis due to aspergillus clavatus"
        ],
        "categories": [
          {
            "ref": "MONDO:0005046",
            "name": "immune system disorder"
          },
          {
            "ref": "MONDO:0005087",
            "name": "respiratory system disorder"
          }
        ],
        "definition": "An extrinsic allergic alveolitis caused by infection with Aspergillus."
      },
      "child_count": 0,
      "reference_id": "MONDO:0002266"
    }
  ],
  "roots": [
    {
      "id": 3133,
      "label": "allergic respiratory disease"
    },
    {
      "id": 7292,
      "label": "aspergillosis"
    }
  ]
}