{
  "id": 16149,
  "label": "bronchiolitis obliterans syndrome",
  "model": {
    "label": "Mondo Disease Ontology (MONDO)",
    "source": 0
  },
  "type_id": 0,
  "reference_id": "MONDO:0015265",
  "properties": {
    "xrefs": [
      "DOID:2799",
      "EFO:0007183",
      "GARD:0005961",
      "HP:0011946",
      "ICD9:466.19",
      "ICD9:491.8",
      "MEDGEN:665",
      "NANDO:1200745",
      "NANDO:2100039",
      "NANDO:2200209",
      "Orphanet:1303",
      "SCTID:40100001",
      "UMLS:C0006272",
      "icd11.foundation:592711730"
    ],
    "synonyms": [
      "BOOP",
      "constrictive bronchiolitis",
      "organised pneumonia",
      "organized pneumonia",
      "bronchiolitis obliterans with obstructive pulmonary disease",
      "BO",
      "bronchiolitis exudativa",
      "bronchiolitis obliterans",
      "obliterative bronchiolitis",
      "organising pneumonia",
      "organizing pneumonia"
    ],
    "categories": [
      {
        "ref": "MONDO:0005087",
        "name": "respiratory system disorder"
      }
    ],
    "definition": "A lung disorder that is mainly associated with chronic allograft dysfunction after lung transplantation and that is characterized by inflammation and fibrosis of bronchiolar walls that reduce the diameter of the bronchioles and result in progressive and irreversible airflow obstruction."
  },
  "isLeaf": false,
  "isRoot": false,
  "child_count": 2,
  "parents": [
    {
      "id": 4545,
      "label": "bronchiolitis",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        6971
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:2942",
          "HP:0011950",
          "ICD9:466.19",
          "MEDGEN:14235",
          "MESH:D001988",
          "NCIT:C39658",
          "SCTID:4120002",
          "UMLS:C0006271"
        ],
        "synonyms": [
          "bronchiolitis",
          "bronchiolitis (disease)",
          "wheezy bronchitis",
          "RSV bronchiolitis",
          "viral bronchiolitis"
        ],
        "categories": [
          {
            "ref": "MONDO:0005087",
            "name": "respiratory system disorder"
          }
        ],
        "definition": "Inflammation of the bronchioles characterized by swelling of the bronchioles and mucus accumulation. It is usually caused by the respiratory syncytial virus and affects children. Signs and symptoms include coughing, wheezing, and shortness of breath."
      },
      "child_count": 6,
      "reference_id": "MONDO:0002465"
    },
    {
      "id": 16615,
      "label": "interstitial lung disease",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        6971
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:3082",
          "EFO:0004244",
          "ICD10CM:J80-J84",
          "MEDGEN:1788738",
          "MESH:D017563",
          "MedDRA:10022611",
          "NCIT:C164315",
          "Orphanet:182095",
          "SCTID:233703007",
          "UMLS:C5441745"
        ],
        "synonyms": [
          "ILD",
          "interstitial lung disease"
        ],
        "categories": [
          {
            "ref": "MONDO:0005087",
            "name": "respiratory system disorder"
          }
        ],
        "definition": "A diverse group of lung diseases that affect the lung parenchyma. They are characterized by an initial inflammation of pulmonary alveoli that extends to the interstitium and beyond leading to diffuse pulmonary fibrosis. Interstitial lung diseases are classified by their etiology (known or unknown causes), and radiological-pathological features."
      },
      "child_count": 14,
      "reference_id": "MONDO:0015925"
    }
  ],
  "children": [
    {
      "id": 25834,
      "label": "transplant-related bronchiolitis obliterans",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        16149
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "GARD:0026942",
          "MEDGEN:1808244",
          "Orphanet:658602",
          "UMLS:C5574736"
        ],
        "categories": [
          {
            "ref": "MONDO:0005087",
            "name": "respiratory system disorder"
          }
        ]
      },
      "child_count": 0,
      "reference_id": "MONDO:0958127"
    },
    {
      "id": 25835,
      "label": "non-transplant-related bronchiolitis obliterans",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        16149
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "GARD:0026943",
          "MEDGEN:1863569",
          "Orphanet:658612",
          "UMLS:C5925142"
        ],
        "categories": [
          {
            "ref": "MONDO:0005087",
            "name": "respiratory system disorder"
          }
        ]
      },
      "child_count": 0,
      "reference_id": "MONDO:0958128"
    }
  ],
  "roots": [
    {
      "id": 4545,
      "label": "bronchiolitis"
    },
    {
      "id": 16615,
      "label": "interstitial lung disease"
    }
  ]
}